2026 ICD-10-CM Diagnosis Code R35.81Nocturnal polyuria

ICD-10-CM Codes›R00–R99›R30-R39›R35

ICD-10-CM R35.81
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R35.81 is a billable ICD-10-CM diagnosis code for nocturnal polyuria. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 695 through 696. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. Coders also document this condition as nocturia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Genitourinary signs and symptoms.

Code Identity

ICD-10-CM Code
R35.81
Billable Status
Yes — Valid for Submission
Code Describes
Nocturnal polyuria
Short Description
Nocturnal polyuria
Same as the full description in the CMS dataset.
Parent Code
R35.8
Other polyuria

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR30-R39Symptoms and signs involving the genitourinary system
CategoryR35Polyuria
This CodeR35.81Nocturnal polyuria

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Nocturia
  • Nocturnal polyuria

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 2 Excludes

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Polyuria
      • nocturnal

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM011
Genitourinary signs and symptoms
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Nocturia

    frequent urination at night that interrupts sleep. it is often associated with outflow obstruction, diabetes mellitus, or bladder inflammation (cystitis).

  • Grade 1 Nocturia, CTCAE

    present

  • Nocturia, CTCAE

    a disorder characterized by the need to get up at night on a regular basis to urinate.

  • Nocturia

    frequent episodes of urination during the night.

  • PDQUALIF - Nocturia

    parkinson's disease quality of life scale (pdqualif) the need to go to the bathroom keeps me up at night.

Patient EducationClinical

Urine and Urination

Your kidneys make urine by filtering wastes and extra water from your blood. The waste is called urea. Your blood carries it to the kidneys. From the kidneys, urine travels down two thin tubes called ureters to the bladder. The bladder stores urine until you are ready to urinate.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement R35.81 replaces the following previously assigned code(s):

  • R35.8 - Other polyuria
FY 2022AddedAdded to the ICD-10-CM code setEffective October 1, 2021.
FY 2023–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R35.81Overview

Is R35.81 (Other polyuria) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report nocturnal polyuria on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does R35.81 group to?

When nocturnal polyuria is the principal diagnosis on an inpatient stay, it groups to MS-DRG 695, 696, with relative weights from 0.6890 to 1.1438 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R35.81 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the nocturnal polyuria is established, that condition takes the principal position instead.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.