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  6. 2026 ICD-10-CM Code Q87.88

2026 ICD-10-CM Diagnosis Code Q87.88

CTNNB1 syndrome

ICD-10-CM Code:
Q87.88
ICD-10 Code for:
CTNNB1 syndrome
Is Billable?
Yes - Valid for Submission
Code Navigator:

Q87.88 is a billable diagnosis code used to specify a medical diagnosis of ctnnb1 syndrome. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

Code Classification

  • Congenital malformations, deformations and chromosomal abnormalities
    Q00-Q99
    • Other congenital malformations
      Q80-Q89
      • Other specified congenital malformation syndromes affecting multiple systems
        Q87

New 2026 ICD-10-CM Code

Q87.88 is new to ICD-10-CM code set for the FY 2026, effective October 1, 2025. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2025. This is a new and revised code for the FY 2026 (October 1, 2025 - September 30, 2026).

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Use Additional Code

Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
  • code, if applicable, for associated conditions such as:
  • cerebral palsy G80
  • congenital heart malformations Q20.0 Q24.9
  • developmental disorder of speech and language F80
  • exudative retinopathy H35.02
  • intellectual disability F70 F79
  • microcephaly Q02

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Index of External Cause of Injuries

References found for this diagnosis code in the External Cause of Injuries Index:

    • Syndrome
      • CTNNB1

Present on Admission (POA)

Q87.88 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA Indicator: Y

Reason: Diagnosis was present at time of inpatient admission.

CMS Pays CC/MCC DRG? YES

POA Indicator: N

Reason: Diagnosis was not present at time of inpatient admission.

CMS Pays CC/MCC DRG? NO

POA Indicator: U

Reason: Documentation insufficient to determine if the condition was present at the time of inpatient admission.

CMS Pays CC/MCC DRG? NO

POA Indicator: W

Reason: Clinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.

CMS Pays CC/MCC DRG? YES

POA Indicator: 1

Reason: Unreported/Not used - Exempt from POA reporting.

CMS Pays CC/MCC DRG? NO

Replacement Code

Q8788 replaces the following previously assigned ICD-10-CM code(s):

  • Q87.89 - Oth congenital malformation syndromes, NEC

Code History

  • FY 2026 - Code Added, effective from 10/1/2025 through 9/30/2026