2027 ICD-10-CM Diagnosis Code O75.3Other infection during labor

ICD-10-CM Codes›O00-O9A›O60-O77›O75

ICD-10-CM O75.3
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

O75.3 is a billable ICD-10-CM diagnosis code for other infection during labor. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 817 through 819, 831 through 833. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 221 closely related codes. The code is restricted by the Medicare Code Editor to maternity cases (age 9 through 64). Coders also document this condition as generalized infection during labor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Complications specified during childbirth.

Code Identity

ICD-10-CM Code
O75.3
Billable Status
Yes — Valid for Submission
Code Describes
Other infection during labor
Short Description
Other infection during labor
Same as the full description in the CMS dataset.
Parent Code
Other complications of labor and delivery, not elsewhere classified

Code Classification

ChapterO00-O9APregnancy, childbirth and the puerperium
SectionO60-O77Complications of labor and delivery
CategoryO75Other complications of labor and delivery, not elsewhere classified
This CodeO75.3Other infection during labor

Code EditsBilling

Medicare Code Editor checks that affect claim validity for O75.3.

The Medicare Code Editor detects inconsistencies in maternity cases by checking a patient's age and any diagnosis on the patient's record. The maternity code edits apply to patients age ange is 9–64 years inclusive (e.g., diabetes in pregnancy, antepartum pulmonary complication).

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Generalized infection during labor
  • Sepsis during labor

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to O75.3: its own notes plus those printed at O75 and Chapter 15. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Sepsis during labor

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • supervision of normal pregnancy (Z34.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From O75 Other complications of labor and delivery, not elsewhere classified applies to 10 codes
  • puerperal (postpartum) infection (O86.-)
  • puerperal (postpartum) sepsis (O85)
From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • mental and behavioral disorders associated with the puerperium (F53.-)
  • obstetrical tetanus (A34)
  • postpartum necrosis of pituitary gland (E23.0)
  • puerperal osteomalacia (M83.0)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

On O75.3 itself
  • code (B95-B97), to identify infectious agent
From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • code, if applicable, from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known.

Notes

General instructions on how these codes are used.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • CODES FROM THIS CHAPTER ARE FOR USE ONLY ON MATERNAL RECORDS, NEVER ON NEWBORN RECORDS
  • Codes from this chapter are for use for conditions related to or aggravated by the pregnancy, childbirth, or by the puerperium (maternal causes or obstetric causes)
  • Trimesters are counted from the first day of the last menstrual period. They are defined as follows:
  • 1st trimester- less than 14 weeks 0 days
  • 2nd trimester- 14 weeks 0 days to less than 28 weeks 0 days
  • 3rd trimester- 28 weeks 0 days until delivery

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name O75.3, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming O75.3: they are not reported together with it, unless the two conditions are unrelated.

  • Block N70-N77 Inflammatory diseases of female pelvic organs
    pregnancy, childbirth and the puerperium (O23.-, O75.3, O85, O86.-)

Excludes2 3

These codes carry an Excludes2 note naming O75.3: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block N30-N39 Other diseases of the urinary system
    pregnancy, childbirth and the puerperium (O23.-, O75.3, O86.2-)
  • O85 Puerperal sepsis
    sepsis during labor (O75.3)
  • O86 Other puerperal infections
    infection during labor (O75.3)

Code First 2

These codes say to code first a condition named in the note, and O75.3 is one of the conditions named.

  • A40 Streptococcal sepsis
    streptococcal sepsis during labor (O75.3)
  • A41 Other sepsis
    sepsis during labor (O75.3)

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PRG023
Complications specified during childbirth
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Childbirth Problems

Childbirth is the process of giving birth to a baby. It includes labor and delivery. Usually everything goes well, but problems can happen. They may cause a risk to the mother, baby, or both. Some of the more common childbirth problems include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert O75.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
659.31 Septicem in labor-deliv
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About O75.3Overview

What is the ICD-10 code for other infection during labor?

The ICD-10-CM code for other infection during labor is O75.3 (sometimes written as O753). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is O75.3 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other infection during labor on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does O75.3 group to?

When other infection during labor is the principal diagnosis on an inpatient stay, it groups to MS-DRG 833, 832, 831, 819, 818, 817, with relative weights from 0.5000 to 1.7586 depending on complications. Higher weights mean higher Medicare reimbursement.

Is O75.3 a CC or MCC?

CMS lists O75.3 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 221 closely related codes in its exclusion list.

Who can O75.3 be reported for?

The Medicare Code Editor checks other infection during labor against patient demographics: this code is intended for maternity cases (age 9 through 64). Claims outside these limits are flagged as inconsistent.