2026 ICD-10-CM Diagnosis Code D00.01Carcinoma in situ of labial mucosa and vermilion border

ICD-10-CM CodesC00–D49D00-D09D00

ICD-10-CM D00.01
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D00.01 is a billable ICD-10-CM diagnosis code for carcinoma in situ of labial mucosa and vermilion border. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 146 through 148. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Head and neck cancers - lip and oral cavity.

Code Identity

ICD-10-CM Code
D00.01
Billable Status
Yes — Valid for Submission
Code Describes
Carcinoma in situ of labial mucosa and vermilion border
Short Description
Carcinoma in situ of labial mucosa and vermilion border
Same as the full description in the CMS dataset.
Parent Code
Carcinoma in situ of lip, oral cavity and pharynx

Code Classification

ChapterC00–D49Neoplasms
SectionD00-D09In situ neoplasms
CategoryD00Carcinoma in situ of oral cavity, esophagus and stomach
This CodeD00.01Carcinoma in situ of labial mucosa and vermilion border

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Carcinoma in situ of commissure of lip
  • Carcinoma in situ of frenum of lip
  • Carcinoma in situ of frenum of lower lip
  • Carcinoma in situ of frenum of upper lip
  • Carcinoma in situ of inner aspect of lip
  • Carcinoma in situ of lip
  • Carcinoma in situ of lower labial mucosa
  • Carcinoma in situ of oral cavity
  • Carcinoma in situ of oral cavity, lips, salivary glands
  • Carcinoma in situ of salivary gland
  • Carcinoma in situ of upper labial mucosa
  • Carcinoma in situ of vermilion border of lip
  • Carcinoma in situ of vermilion border of lower lip
  • Carcinoma in situ of vermilion border of upper lip
  • Carcinoma in situ of vermilion of lip
  • Carcinoma in situ of vermilion of lower lip
  • Carcinoma in situ of vermilion of upper lip
  • Neoplasm of commissure of lip
  • Neoplasm of frenulum of lower lip
  • Neoplasm of frenulum of upper lip
  • Neoplasm of oral cavity and lip and salivary gland
  • Neoplasm of vermilion border of upper lip
  • Primary malignant neoplasm of vermilion border of lip
  • Primary squamous cell carcinoma of lip
  • Primary squamous cell carcinoma of vermilion border of lip

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO002
Head and neck cancers - lip and oral cavity
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
commissureC00.6C79.89D00.01D10.39D37.01D49.0
commissure labial, lipC00.6C79.89D00.01D10.39D37.01D49.0
labial [See Also: Neoplasm, lip]C00.9C79.89D00.01D10.0D37.01D49.0
lipC00.9C79.89D00.01D10.0D37.01D49.0
lip commissureC00.6C79.89D00.01D10.0D37.01D49.0
lip externalC00.2C79.89D00.01D10.0D37.01D49.0
lip external lowerC00.1C79.89D00.01D10.0D37.01D49.0
lip external upperC00.0C79.89D00.01D10.0D37.01D49.0
lip internalC00.5C79.89D00.01D10.0D37.01D49.0
lip internal lowerC00.4C79.89D00.01D10.0D37.01D49.0
lip internal upperC00.3C79.89D00.01D10.0D37.01D49.0
lip lipstick areaC00.2C79.89D00.01D10.0D37.01D49.0
lip lipstick area lowerC00.1C79.89D00.01D10.0D37.01D49.0
lip lipstick area upperC00.0C79.89D00.01D10.0D37.01D49.0
lip lowerC00.1C79.89D00.01D10.0D37.01D49.0
lip lower internalC00.4C79.89D00.01D10.0D37.01D49.0
lip upperC00.0C79.89D00.01D10.0D37.01D49.0
lip upper internalC00.3C79.89D00.01D10.0D37.01D49.0
lip vermilion borderC00.2C79.89D00.01D10.0D37.01D49.0
lip vermilion border lowerC00.1C79.89D00.01D10.0D37.01D49.0
lip vermilion border upperC00.0C79.89D00.01D10.0D37.01D49.0

Patient EducationClinical

Oral Cancer

Oral cancer is cancer of the mouth. It is a type of head and neck cancer. Most oral cancers are squamous cell cancers. They begin in the flat cells that cover the surfaces of your mouth, tongue, and lips. The cancer cells may spread into deeper tissue as the cancer grows.

The full article covers:

  • What is oral cancer?
  • Who is more likely to develop oral cancer?
  • What are the symptoms of oral cancer?
  • How is oral cancer diagnosed?
  • What are the treatments for oral cancer?
  • Can oral cancer be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D00.01 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
230.0 Ca in situ oral cav/phar
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D00.01Overview

Is D00.01 (Carcinoma in situ of lip, oral cavity and pharynx) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report carcinoma in situ of labial mucosa and vermilion border on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D00.01 group to?

When carcinoma in situ of labial mucosa and vermilion border is the principal diagnosis on an inpatient stay, it groups to MS-DRG 146, 147, 148, with relative weights from 0.7971 to 2.1174 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D00.01?

Under the General Equivalence Mappings, carcinoma in situ of labial mucosa and vermilion border converts to ICD-9-CM 230.0 (ca in situ oral cav/phar). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.