2025 ICD-10-CM Diagnosis Code C88.91

Malignant immunoproliferative disease, unspecified, in remission

ICD-10-CM Code:
C88.91
ICD-10 Code for:
Malignant immunoproliferative disease, unsp, in remission
Is Billable?
Yes - Valid for Submission
Code Navigator:

C88.91 is a billable diagnosis code used to specify a medical diagnosis of malignant immunoproliferative disease, unspecified, in remission. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.

The following anatomical sites found in the Table of Neoplasms reference the parent code C88.9 of the current diagnosis code given the correct histological behavior: Neoplasm, neoplastic immunoproliferative NEC .

Unspecified diagnosis codes like C88.91 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

Code Classification

  • Neoplasms
    (C00–D49)
    • Malignant neoplasms of lymphoid, hematopoietic and related tissue
      (C81-C96)
      • Malignant immunoproliferative diseases and certain other B-cell lymphomas
        (C88)

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Immunoproliferative neoplasm in remission

New 2025 ICD-10-CM Code

C88.91 is new to ICD-10-CM code set for the FY 2025, effective October 1, 2024. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2024. This is a new and revised code for the FY 2025 (October 1, 2024 - September 30, 2025).

Replacement Code

C8891 replaces the following previously assigned ICD-10-CM code(s):

  • Z85.79 - Prsnl hx of malig neoplm of lymphoid, hematpoetc & rel tiss

Table of Neoplasms

The parent code C88.9 of the current diagnosis code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»Neoplasm, neoplastic
  »immunoproliferative NEC
C88.9     

Code History