ICD-10-CM Code C88.2

Heavy chain disease

Version 2021 Billable Code

Valid for Submission

C88.2 is a billable code used to specify a medical diagnosis of heavy chain disease. The code is valid for the fiscal year 2021 for the submission of HIPAA-covered transactions. The ICD-10-CM code C88.2 might also be used to specify conditions or terms like delta heavy chain disease, epsilon heavy chain disease, gamma heavy chain disease , heavy chain disease, monoclonal gamma heavy chain present, monoclonal mu heavy chain present, etc

ICD-10:C88.2
Short Description:Heavy chain disease
Long Description:Heavy chain disease

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code C88.2:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Franklin disease
  • Gamma heavy chain disease
  • Mu heavy chain disease

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code C88.2 are found in the index:


Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Delta heavy chain disease
  • Epsilon heavy chain disease
  • Gamma heavy chain disease
  • Heavy chain disease
  • Monoclonal gamma heavy chain present
  • Monoclonal mu heavy chain present
  • Mu heavy chain disease

Clinical Information

  • HEAVY CHAIN DISEASE-. a disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. the amino acid sequences of the n amino terminal regions of these chains are normal but they have a deletion extending from part of the variable domain through the first domain of the constant region so that they cannot form cross links to the light chains. the defect arises through faulty coupling of the variable v and constant c region genes.
  • IMMUNOPROLIFERATIVE SMALL INTESTINAL DISEASE-. a condition that is caused by hyperplasia of lymphocytes in the small intestine intestine small and the mesenteric lymph nodes. these lymphocytes produce an anomalous alpha heavy chain protein. generally these ipsid patients have either concurrent lymphoma or develop lymphoma within a few years. the disease was first described in the mediterranean region and is characterized by malabsorption; weight loss; diarrhea; and steatorrhea.

Diagnostic Related Groups

The ICD-10 code C88.2 is grouped in the following groups for version MS-DRG V38.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2021.

  • 820 - LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH MCC
  • 821 - LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH CC
  • 822 - LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITHOUT CC/MCC

Convert C88.2 to ICD-9

  • 203.80 - Oth imno npl wo ach rmsn (Approximate Flag)
  • 203.81 - Oth imnprfl npl w rmsn (Approximate Flag)

Code Classification

  • Neoplasms (C00–D48)
    • Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
      • Malig immunoproliferative dis and certain oth B-cell lymph (C88)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Lymphoma

Also called: Non-Hodgkin lymphoma

Lymphoma is a cancer of a part of the immune system called the lymph system. There are many types of lymphoma. One type is Hodgkin disease. The rest are called non-Hodgkin lymphomas.

Non-Hodgkin lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors don't know why a person gets non-Hodgkin lymphoma. You are at increased risk if you have a weakened immune system or have certain types of infections.

Non-Hodgkin lymphoma can cause many symptoms, such as

  • Swollen, painless lymph nodes in the neck, armpits or groin
  • Unexplained weight loss
  • Fever
  • Soaking night sweats
  • Coughing, trouble breathing or chest pain
  • Weakness and tiredness that don't go away
  • Pain, swelling or a feeling of fullness in the abdomen

Your doctor will diagnose lymphoma with a physical exam, blood tests, a chest x-ray, and a biopsy. Treatments include chemotherapy, radiation therapy, targeted therapy, biological therapy, or therapy to remove proteins from the blood. Targeted therapy uses substances that attack cancer cells without harming normal cells. Biologic therapy boosts your body's own ability to fight cancer. If you don't have symptoms, you may not need treatment right away. This is called watchful waiting.

NIH: National Cancer Institute

  • After chemotherapy - discharge (Medical Encyclopedia)
  • B-cell leukemia/lymphoma panel (Medical Encyclopedia)
  • Bone marrow transplant (Medical Encyclopedia)
  • Burkitt lymphoma (Medical Encyclopedia)
  • Lymph node biopsy (Medical Encyclopedia)
  • Non-Hodgkin lymphoma (Medical Encyclopedia)
  • Non-Hodgkin lymphoma - children (Medical Encyclopedia)

[Learn More]