2025 ICD-10-CM Diagnosis Code C88.20
Heavy chain disease not having achieved remission
- ICD-10-CM Code:
- C88.20
- ICD-10 Code for:
- Heavy chain disease not having achieved remission
- Is Billable?
- Yes - Valid for Submission
- Code Navigator:
C88.20 is a billable diagnosis code used to specify a medical diagnosis of heavy chain disease not having achieved remission. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Gamma heavy chain disease
- Glomerular disease due to neoplastic disease
- Heavy chain deposition disease
- Heavy chain disease
- Monoclonal abnormal heavy chain protein devoid of light chains detected
- Monoclonal abnormal heavy chain protein devoid of light chains detected
- Monoclonal abnormal heavy chain protein devoid of light chains detected
- Monoclonal abnormal heavy chain protein devoid of light chains detected
- Monoclonal gamma heavy chain detected
- Monoclonal mu heavy chain detected
- Mu heavy chain disease
- Nodular glomerulosclerosis due to heavy chain deposition disease
- Non-amyloid monoclonal immunoglobulin deposition disease
Clinical Information
Heavy Chain Disease
a disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. the amino acid sequences of the n-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. the defect arises through faulty coupling of the variable (v) and constant (c) region genes.Immunoproliferative Small Intestinal Disease
a condition that is caused by hyperplasia of lymphocytes in the small intestine (intestine, small) and the mesenteric lymph nodes. these lymphocytes produce an anomalous alpha heavy chain protein. generally, these ipsid patients have either concurrent lymphoma or develop lymphoma within a few years. the disease was first described in the mediterranean region and is characterized by malabsorption; weight loss; diarrhea; and steatorrhea.
New 2025 ICD-10-CM Code
C88.20 is new to ICD-10-CM code set for the FY 2025, effective October 1, 2024. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2024. This is a new and revised code for the FY 2025 (October 1, 2024 - September 30, 2025).
Tabular List of Diseases and Injuries
The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.
Inclusion Terms
Inclusion TermsThese terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Franklin disease NOS
- Franklin disease not having achieved remission
- Franklin disease with failed remission
- Gamma heavy chain disease NOS
- Gamma heavy chain disease not having achieved remission
- Gamma heavy chain disease with failed remission
- Heavy chain disease NOS
- Heavy chain disease with failed remissionMu heavy chain disease not having achieved remission
- Mu heavy chain disease NOS
- Mu heavy chain disease not having achieved remission
- Mu heavy chain disease with failed remission
Replacement Code
C8820 replaces the following previously assigned ICD-10-CM code(s):
- C88.2 - Heavy chain disease
