2026 ICD-10-CM Diagnosis Code C41.9Malignant neoplasm of bone and articular cartilage, unspecified
ICD-10-CM Codes›C00–D49›C40-C41›C41
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Risk Adjusts — HCC 21
- Chronic Condition
C41.9 is a billable ICD-10-CM diagnosis code for malignant neoplasm of bone and articular cartilage, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 542 through 544. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 25 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Bone cancer.
For Medicare Advantage risk adjustment, C41.9 maps to CMS-HCC Category 21 (Lymphoma and Other Cancers) under the V28 model, adding a risk factor of about 0.671 for a community, non-dual, aged beneficiary in payment year 2026.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
C41.9 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2026.
Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Carcinoma of bone, connective tissue, skin and breast
- Chondrosarcoma
- Chondrosarcoma of bone
- Clear cell chondrosarcoma
- Conventional osteosarcoma
- Dedifferentiated chondrosarcoma
- Diaphyseal medullary stenosis with bone malignancy
- Disseminated Langerhans cell histiocytosis of bone
- Ewing's sarcoma of bone
- Extraskeletal mesenchymal chondrosarcoma
- Extraskeletal myxoid chondrosarcoma
- High-grade surface osteosarcoma
- Langerhans cell histiocytosis, disseminated
- Large cell Ewing sarcoma of bone
- Local recurrence of malignant neoplasm of bone
- Low-grade central osteosarcoma
- Macrocytosis - no anemia
- Malignant giant cell tumor of bone
- Malignant neoplasm of articular cartilage
- Malignant neoplasm of bone
- Malignant neoplasm of bone, connective tissue, skin and breast
- Malignant neoplasm of skeletal system
- Malignant neoplasm of vertebra
- Mesenchymal chondrosarcoma
- Metastatic extraskeletal osteosarcoma
- Metastatic malignant neoplasm to articular cartilage
- Metastatic malignant neoplasm to clavicle
- Metastatic malignant neoplasm to long bone of upper limb
- Metastatic malignant neoplasm to rib
- Metastatic malignant neoplasm to sternum
- Metastatic malignant neoplasm to vertebral column
- Metastatic osteosarcoma to articular cartilage of clavicle
- Metastatic osteosarcoma to articular cartilage of rib
- Metastatic osteosarcoma to articular cartilage of sternum
- Metastatic osteosarcoma to articular cartilage of vertebra
- Metastatic osteosarcoma to bone
- Metastatic osteosarcoma to bone of clavicle
- Metastatic osteosarcoma to bone of head
- Metastatic osteosarcoma to bone of rib
- Metastatic osteosarcoma to bone of sternum
- Metastatic osteosarcoma to bone of vertebra
- Non-anemic red cell disorder
- Osteosarcoma
- Osteosarcoma of articular cartilage of clavicle
- Osteosarcoma of articular cartilage of rib
- Osteosarcoma of articular cartilage of sternum
- Osteosarcoma of articular cartilage of vertebra
- Osteosarcoma of bone
- Osteosarcoma of bone of clavicle
- Osteosarcoma of bone of head
- Osteosarcoma of bone of rib
- Osteosarcoma of bone of upper limb
- Osteosarcoma of bone of vertebra
- Osteosarcoma of sternum
- Osteosarcoma, limb anomalies, erythroid macrocytosis syndrome
- Overlapping malignant neoplasm of bone and articular cartilage
- Parosteal osteosarcoma
- Periosteal chondrosarcoma
- Periosteal osteosarcoma
- Primary chondrosarcoma of articular cartilage
- Primary chondrosarcoma of bone
- Primary Ewing sarcoma of bone
- Primary large cell Ewing sarcoma of bone
- Primary malignant neoplasm of articular cartilage
- Primary malignant neoplasm of bone
- Primary osteosarcoma
- Primary osteosarcoma of bone
- Sarcoma of bone
- Sarcoma of bone and connective tissue
- Sarcoma of clavicle
- Sarcoma of rib
- Sarcoma of sternum
- Sarcoma of vertebra
- Small cell osteosarcoma
- Telangiectatic osteosarcoma
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Osteitis See Also: Osteomyelitis;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Osteosarcoma
a sarcoma originating in bone-forming cells, affecting the ends of long bones. it is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (from stedman, 25th ed)Osteosarcoma, Juxtacortical
a form of osteogenic sarcoma of relatively low malignancy, probably arising from the periosteum and initially involving cortical bone and adjacent connective tissue. it occurs in middle-aged as well as young adults and most commonly affects the lower part of the femoral shaft. (stedman, 25th ed)Chondrosarcoma
a slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with enchondromatosis. (stedman, 25th ed)Chondrosarcoma, Clear Cell
a chondrosarcoma of adolescence to old age of the proximal epiphyses of long bones. it has variably clear cytoplasm of the mostly neoplastic chondrocytes with little intervening matrix.Chondrosarcoma, Mesenchymal
a rare aggressive variant of chondrosarcoma, characterized by a biphasic histologic pattern of small compact cells intermixed with islands of cartilaginous matrix. mesenchymal chondrosarcomas have a predilection for flat bones; long tubular bones are rarely affected. they tend to occur in the younger age group and are highly metastatic. (devita jr et al., cancer: principles & practice of oncology, 3d ed, p1456)Enchondromatosis
benign growths of cartilage in the metaphyses of several bones.
Table of NeoplasmsClinical
Anatomical sites in the Table of Neoplasms that reference this code family.
| Site | Malig. Primary | Malig. Secondary | Ca in situ | Benign | Uncertain | Unspec. |
|---|---|---|---|---|---|---|
| bone (periosteum) | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| bone (periosteum) › cartilage NEC | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| bone (periosteum) › cuneiform | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| joint NEC [See Also: Neoplasm, bone] | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| skeleton, skeletal NEC | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
Patient EducationClinical
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Convert C41.9 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About C41.9Overview
What is the ICD-10 code for malignant neoplasm of bone and articular cartilage, unspecified?
The ICD-10-CM code for malignant neoplasm of bone and articular cartilage, unspecified is C41.9 (sometimes written as C419). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Is C41.9 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of bone and articular cartilage, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does C41.9 group to?
When malignant neoplasm of bone and articular cartilage, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 542, 543, 544, with relative weights from 0.7546 to 1.7665 depending on complications. Higher weights mean higher Medicare reimbursement.
Is C41.9 a CC or MCC?
CMS lists C41.9 as a CC (complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 25 closely related codes in its exclusion list.
What is the ICD-9 equivalent of C41.9?
Under the General Equivalence Mappings, malignant neoplasm of bone and articular cartilage, unspecified converts to ICD-9-CM 170.9 (malig neopl bone NOS). The mapping is approximate, so confirm the match fits the documentation.
What HCC is C41.9?
C41.9 (malignant neoplasm of bone and articular cartilage, unspecified) maps to CMS-HCC Category 21 (Lymphoma and Other Cancers), commonly written as HCC 21, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2026. It mapped to HCC 10 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 22.
Does C41.9 risk-adjust for Medicare Advantage payment?
Yes. When documented and reported on a Medicare Advantage encounter, C41.9 adds a risk adjustment factor of about 0.671 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.493 to 0.739 depending on the payment segment). A more severe related category (HCC 17, HCC 18, HCC 19, and HCC 20) supersedes it when both are reported. See the full factor table on the HCC 21 category page.