2024 ICD-10-CM Diagnosis Code E80.6

Other disorders of bilirubin metabolism

ICD-10-CM Code:
E80.6
ICD-10 Code for:
Other disorders of bilirubin metabolism
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)
    • Metabolic disorders
      (E70-E88)
      • Disorders of porphyrin and bilirubin metabolism
        (E80)

E80.6 is a billable diagnosis code used to specify a medical diagnosis of other disorders of bilirubin metabolism. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acquired hyperbilirubinemia
  • Conjugated hyperbilirubinemia
  • Cyclic premenstrual unconjugated hyperbilirubinemia
  • Delayed conjugation of bilirubin
  • Disorders of bilirubin excretion
  • Dubin-Johnson syndrome
  • Hyperbilirubinemia
  • Hyperbilirubinemia - conjugated - type III
  • Inherited disorder of bilirubin metabolism
  • Inherited disorder of bilirubin metabolism
  • Neonatal jaundice with Dubin-Johnson syndrome
  • Neonatal jaundice with Rotor's syndrome
  • Physiological hyperbilirubinemia
  • Rotor syndrome
  • Unconjugated hyperbilirubinemia
  • Unconjugated hyperbilirubinemia

Clinical Classification

Clinical Information

  • Crigler-Najjar Syndrome

    a familial form of congenital hyperbilirubinemia transmitted as an autosomal recessive trait. it is characterized by icterus and brain damage caused by a glucuronyl transferase deficiency in the liver and faulty bilirubin conjugation.
  • Gilbert Disease

    a benign familial disorder, transmitted as an autosomal dominant trait. it is characterized by low-grade chronic hyperbilirubinemia with considerable daily fluctuations of the bilirubin level.
  • Hyperbilirubinemia

    a condition characterized by an abnormal increase of bilirubin in the blood, which may result in jaundice. bilirubin, a breakdown product of heme, is normally excreted in the bile or further catabolized before excretion in the urine.
  • Hyperbilirubinemia, Hereditary

    inborn errors of bilirubin metabolism resulting in excessive amounts of bilirubin in the circulating blood, either because of increased bilirubin production or because of delayed clearance of bilirubin from the blood.
  • Hyperbilirubinemia, Neonatal

    accumulation of bilirubin, a breakdown product of heme proteins, in the blood during the first weeks of life. this may lead to neonatal jaundice. the excess bilirubin may exist in the unconjugated (indirect) or the conjugated (direct) form. the condition may be self-limiting (physiological neonatal jaundice) or pathological with toxic levels of bilirubin.
  • Jaundice, Chronic Idiopathic

    a benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. there is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. affected persons may be asymptomatic or have vague constitutional or gastrointestinal symptoms. the liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Dubin-Johnson syndrome
  • Rotor's syndrome

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert E80.6 to ICD-9-CM

  • ICD-9-CM Code: 277.4 - Dis bilirubin excretion
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat.

A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process. When this happens, you might have too much of some substances or too little of other ones that you need to stay healthy. There are different groups of disorders. Some affect the breakdown of amino acids, carbohydrates, or lipids. Another group, mitochondrial diseases, affects the parts of the cells that produce the energy.

You can develop a metabolic disorder when some organs, such as your liver or pancreas, become diseased or do not function normally. Diabetes is an example.


[Learn More in MedlinePlus]

Dubin-Johnson syndrome

Dubin-Johnson syndrome is a condition characterized by jaundice, which is a yellowing of the skin and whites of the eyes. In most affected people jaundice appears during adolescence or early adulthood. Jaundice is typically the only feature of Dubin-Johnson syndrome, but some people can experience weakness, mild abdominal pain, nausea, or vomiting. In most people with Dubin-Johnson syndrome, certain deposits build up in the liver but do not seem to impair liver function. The deposits make the liver appear black when viewed with medical imaging.

Rarely, jaundice develops soon after birth in individuals with Dubin-Johnson syndrome. Affected infants typically also have enlarged livers (hepatomegaly) and a severely reduced ability to produce and release a digestive fluid called bile (cholestasis). As these children get older, their liver problems go away and they usually do not have any related health problems later in life.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.