ICD-10-CM Use Additional Code Notes · Chapter 4 · FY 2027 E00-E89

Use Additional Code Notes in Chapter 4: Endocrine, nutritional and metabolic diseases ICD-10-CM

A Use Additional Code note means a second code should be added, after this one, to fully describe the condition. In Chapter 4 (E00-E89), notes printed in the chapter name other codes 88 times, and Use Additional Code Notes anywhere in the Tabular List name the chapter’s codes 31 times, covering 13 distinct codes, categories and ranges. Switch views to read the list either way.

✓ From the official FY 2027 ICD-10-CM Tabular ListDefinitions follow the Official Guidelines, Section I.A
88
References in Its Notes
31
References to Its Codes
13
Chapter Codes Named
E00-E89
Chapter 4
Chapter 4

Use Additional Code Notes by the code that carries the note

59 of 59 shown
  • E00 Congenital iodine-deficiency syndrome applies to 4 codes
    • code (F70-F79) to identify associated intellectual disabilities.
  • E03.2 Hypothyroidism due to medicaments and other exogenous substances
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E06.0 Acute thyroiditis
    • code (B95-B97) to identify infectious agent.
  • E06.4 Drug-induced thyroiditis
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E08 Diabetes mellitus due to underlying condition applies to 86 codes
    • injectable non-insulin antidiabetic drugs (Z79.85)
    • insulin (Z79.4)
    • oral antidiabetic drugs (Z79.84)
    • oral hypoglycemic drugs (Z79.84)
  • E08.22 Diabetes mellitus due to underlying condition with diabetic chronic kidney disease
    • code to identify stage of chronic kidney disease (N18.1-N18.6)
  • E08.39 Diabetes mellitus due to underlying condition with other diabetic ophthalmic complication
  • E08.621 Diabetes mellitus due to underlying condition with foot ulcer
  • E08.622 Diabetes mellitus due to underlying condition with other skin ulcer
  • E08.64 Diabetes mellitus due to underlying condition with hypoglycemia applies to 2 codes
    • code for hypoglycemia level, if applicable (E16.A-)
  • E09 Drug or chemical induced diabetes mellitus applies to 86 codes
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
    • injectable non-insulin antidiabetic drugs (Z79.85)
    • insulin (Z79.4)
    • oral antidiabetic drugs (Z79.84)
    • oral hypoglycemic drugs (Z79.84)
  • E09.22 Drug or chemical induced diabetes mellitus with diabetic chronic kidney disease
    • code to identify stage of chronic kidney disease (N18.1-N18.6)
  • E09.39 Drug or chemical induced diabetes mellitus with other diabetic ophthalmic complication
  • E09.621 Drug or chemical induced diabetes mellitus with foot ulcer
  • E09.622 Drug or chemical induced diabetes mellitus with other skin ulcer
  • E09.64 Drug or chemical induced diabetes mellitus with hypoglycemia applies to 2 codes
    • code for hypoglycemia level, if applicable (E16.A-)
  • E10.22 Type 1 diabetes mellitus with diabetic chronic kidney disease
    • code to identify stage of chronic kidney disease (N18.1-N18.6)
  • E10.39 Type 1 diabetes mellitus with other diabetic ophthalmic complication
  • E10.621 Type 1 diabetes mellitus with foot ulcer
  • E10.622 Type 1 diabetes mellitus with other skin ulcer
  • E10.64 Type 1 diabetes mellitus with hypoglycemia applies to 2 codes
    • code for hypoglycemia level, if applicable (E16.A-)
  • E11 Type 2 diabetes mellitus applies to 87 codes
    • injectable non-insulin antidiabetic drugs (Z79.85)
    • insulin (Z79.4)
    • oral antidiabetic drugs (Z79.84)
    • oral hypoglycemic drugs (Z79.84)
  • E11.22 Type 2 diabetes mellitus with diabetic chronic kidney disease
    • code to identify stage of chronic kidney disease (N18.1-N18.6)
  • E11.39 Type 2 diabetes mellitus with other diabetic ophthalmic complication
  • E11.621 Type 2 diabetes mellitus with foot ulcer
  • E11.622 Type 2 diabetes mellitus with other skin ulcer
  • E11.64 Type 2 diabetes mellitus with hypoglycemia applies to 2 codes
    • code for hypoglycemia level, if applicable (E16.A-)
  • E13 Other specified diabetes mellitus applies to 86 codes
    • injectable non-insulin antidiabetic drugs (Z79.85)
    • insulin (Z79.4)
    • oral antidiabetic drugs (Z79.84)
    • oral hypoglycemic drugs (Z79.84)
  • E13.22 Other specified diabetes mellitus with diabetic chronic kidney disease
    • code to identify stage of chronic kidney disease (N18.1-N18.6)
  • E13.39 Other specified diabetes mellitus with other diabetic ophthalmic complication
  • E13.621 Other specified diabetes mellitus with foot ulcer
  • E13.622 Other specified diabetes mellitus with other skin ulcer
  • E13.64 Other specified diabetes mellitus with hypoglycemia applies to 2 codes
    • code for hypoglycemia level, if applicable (E16.A-)
  • E16.0 Drug-induced hypoglycemia without coma
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
    • code for hypoglycemia level, if applicable (E16.A-)
  • E16.1 Other hypoglycemia
    • code for hypoglycemia level, if applicable (E16.A-)
  • E16.2 Hypoglycemia, unspecified
    • code for hypoglycemia level, if applicable (E16.A-)
  • E22.1 Hyperprolactinemia
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E23.0 Hypopituitarism
    • code, if applicable, for associated cachexia (E88.A)
  • E23.1 Drug-induced hypopituitarism
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E24.2 Drug-induced Cushing's syndrome
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E25.8 Other adrenogenital disorders
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E27.3 Drug-induced adrenocortical insufficiency
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E28.0 Estrogen excess
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E28.1 Androgen excess
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E29.1 Testicular hypofunction
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E61 Deficiency of other nutrient elements applies to 10 codes
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E66 Overweight and obesity applies to 10 codes
    • code to identify body mass index (BMI), if known, for adults (Z68.1-Z68.45) or pediatrics (Z68.5-)
  • E66.1 Drug-induced obesity
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • E72.03 Lowe's syndrome
    • code for associated glaucoma (H42)
  • E83.19 Other disorders of iron metabolism
    • code, if applicable, for idiopathic pulmonary hemosiderosis (J84.03)
  • E84.0 Cystic fibrosis with pulmonary manifestations
  • E86 Volume depletion applies to 3 codes
    • code(s) for any associated disorders of electrolyte and acid-base balance (E87.-)
  • E88.02 Plasminogen deficiency
    • hydrocephalus (G91.4)
    • otitis media (H67.-)
    • respiratory disorder related to plasminogen deficiency (J99)
  • E88.14 HIV-associated lipodystrophy
    • code for adverse effect, if applicable, to identify drug (T37.5X5-)
  • E88.3 Tumor lysis syndrome
    • code for adverse effect, if applicable, to identify drug (T45.1X5)
  • E88.81 Metabolic syndrome and other insulin resistance applies to 4 codes
  • E88.82 Obesity due to disruption of MC4R pathway
    • code, if applicable, to identify associated manifestations, such as polyphagia (R63.2)
    • code to identify body mass index (BMI), if known (Z68.-)
  • E89.1 Postprocedural hypoinsulinemia
  • E89.83 Postprocedural hypoglycemia following a procedure applies to 2 codes
    • code, if known, for hypoglycemia level (E16.A-)

The first view lists notes printed in this chapter (a note on a category or block applies to every code beneath it). The second lists codes of this chapter named by Use Additional Code Notes anywhere in the Tabular List, including notes in other chapters.

Questions About Use Additional Code Notes

What does a Use Additional Code note mean?

A Use Additional Code note tells you to add a second code, reported after the code that carries the note, to describe the condition completely. In an etiology/manifestation pair it sits at the etiology code and points to the manifestation (Section I.A.13). The FY 2027 Tabular List has 1,491 of them; 1,174 name other codes, with 1,438 references to 389 distinct codes, categories and ranges.

Where does the additional code go?

After the code carrying the note. For etiology/manifestation pairs the Guidelines are explicit: the etiology is sequenced first, followed by the manifestation code.

Related References

Source: FY 2027 ICD-10-CM Tabular List (CMS and NCHS) and the ICD-10-CM Official Guidelines for Coding and Reporting FY 2027, Section I.A. ICD List is not affiliated with CMS or NCHS.