2026 ICD-10-CM Diagnosis Code QA0.0149Neurodevelopmental disorder, related to pathogenic variant in other synapse related gene

ICD-10-CM Codes›Q00-Q99›Q90-Q99›QA0

ICD-10-CM QA0.0149
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

QA0.0149 is a billable ICD-10-CM diagnosis code for neurodevelopmental disorder, related to pathogenic variant in other synapse related gene. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. The code is exempt from POA reporting.

Code Identity

ICD-10-CM Code
QA0.0149
Billable Status
Yes — Valid for Submission
Code Describes
Neurodevelopmental disorder, related to pathogenic variant in other synapse related gene
Short Description
Neurodev disord, rel to patho var in other synapse rel gene
Parent Code
QA0.014
Neurodevelopmental disorders, related to pathogenic variants in synapse related genes

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ90-Q99Chromosomal abnormalities, not elsewhere classified
CategoryQA0Neurodevelopmental disorders related to specific genetic pathogenic variants
This CodeQA0.0149Neurodevelopmental disorder, related to pathogenic variant in other synapse related gene

Present on Admission (POA)Billing

QA0.0149 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Other genetic synaptopathy

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • neurodevelopmental
        • other
          • synapse related gene
    • Synaptopathy
      • specified NEC

Code History & ChangesHistory

New Code QA0.0149 was added to the ICD-10-CM code set for FY 2026, effective October 1, 2025.

Replacement QA0.0149 replaces the following previously assigned code(s):

  • F89 - Unspecified disorder of psychological development
FY 2026AddedAdded to the ICD-10-CM code setEffective October 1, 2025.
FY 2026CurrentRevised in the current code setEffective October 1, 2025 through September 30, 2026.

Questions About QA0.0149Overview

Is QA0.0149 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neurodevelopmental disorder, related to pathogenic variant in other synapse related gene on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does QA0.0149 group to?

When neurodevelopmental disorder, related to pathogenic variant in other synapse related gene is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.

Is QA0.0149 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for neurodevelopmental disorder, related to pathogenic variant in other synapse related gene on inpatient claims.