2025 ICD-10-CM Diagnosis Code F89

Approximate Synonyms

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

Clinical Classification

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

Clinical Information

• Insulin Resistance

  diminished effectiveness of insulin in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

• Metabolic Syndrome

  a cluster of symptoms that are risk factors for cardiovascular diseases and type 2 diabetes mellitus. the major components of metabolic syndrome include abdominal obesity; atherogenic dyslipidemia; hypertension; hyperglycemia; insulin resistance; a proinflammatory state; and a prothrombotic (thrombosis) state.

• Achondroplasia

  an autosomal dominant disorder that is the most frequent form of short-limb dwarfism. affected individuals exhibit short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and mid-face hypoplasia, exaggerated lumbar lordosis, limitation of elbow extension, genu varum, and trident hand. (online mendelian inheritance in man, http://www.ncbi.nlm.nih.gov/omim, mim#100800, april 20, 2001)

• Acanthosis Nigricans

  a circumscribed melanosis consisting of a brown-pigmented, velvety verrucosity or fine papillomatosis appearing in the axillae and other body folds. it occurs in association with endocrine disorders, underlying malignancy, administration of certain drugs, or as in inherited disorder.

• Achondrogenesis

  a rare group of disorders characterized by defective development of bones and cartilage.

• Type II Achondrogenesis|Achondrogenesis, Type II|Hypochondrogenesis|Langer-Saldino Achondrogenesis

  an autosomal dominant condition caused by mutation(s) in the col2a1 gene, encoding collagen alpha-1(ii) chain. it is the most severe of a spectrum of disorders caused by mutations in the col2a1 gene, characterized by short limbs, small chest and lungs, and abnormal ossification of the spine and pelvis. often, infants die at birth or shortly thereafter.

• Acanthosis Nigricans

  a melanotic cutaneous lesion that develops in the axilla and other body folds. it may be idiopathic, drug-induced, or it may be associated with the presence of an endocrine disorder or malignancy.

• Hyperandrogenism, Insulin Resistance, Acanthosis Nigricans Syndrome|HAIR-AN Syndrome

  a condition characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans, typically associated with obesity in teenage girls. it is considered to be a subtype of polycystic ovarian syndrome, but may occur in male individuals. etiology is unclear, but some cases may be associated with mutations affecting the tyrosine kinase domain of the insulin receptor.

• Insulin Resistant Diabetes Mellitus with Acanthosis Nigricans and Hyperandrogenism|Type A Insulin Resistance Syndrome

  a syndrome of insulin resistance caused by mutation(s) in the insr gene, encoding the insulin receptor. this condition is characterized by a clinical triad of hyperinsulinemia, acanthosis nigricans, and hyperandrogenism without lipodystrophy. this is the least severe of a spectrum of disorders; the other two conditions are rabson-mendenhall syndrome and donohoe syndrome.

• Alcohol Related Neurodevelopmental Disorder|ARND

  a cognitive and neurological disorder due to fetal intrauterine exposure to maternal alcohol consumption. typically, this presents without facies or other growth abnormalities.

• Autism Spectrum Disorder|Pervasive Developmental Disorders

  a spectrum of developmental disorders that includes autism, asperger syndrome, and rett syndrome. signs and symptoms include poor communication skills, defective social interactions, and repetitive behaviors.

• Dental Developmental Disorder|Tooth Development Disorder|Tooth development disorder

  a disorder of the teeth arising during odontogenesis.

• Developmental Disorder

  a disorder diagnosed in childhood that is marked by either physical or mental impairment or both, which in turn affects the child from achieving age related developmental milestones.

• Fetal Neurodevelopmental Disorder

  a fetal affliction that has a neurological basis and manifests as a developmental disability.

• Intellectual Developmental Disorder with Cardiac Arrhythmia|IDDCA

  an autosomal recessive condition caused by mutation(s) in the gnb5 gene, encoding guanine nucleotide-binding protein subunit beta-5. it is characterized by severe intellectual disability, poor speech acquisition, and cardiac arrhythmia. biallelic missense mutation in the gnb5 gene can cause language delay and attention deficit-hyperactivity disorder/cognitive impairment with or without cardiac arrhythmia, which is a less-severe disorder with overlapping features.

• Intellectual Developmental Disorder, X-linked, Syndromic, Bain Type|Bain Type of X-linked Syndromic Intellectual Disability|MRXSB

  an x-linked dominant condition caused by mutation(s) in the hnrnph2 gene, encoding heterogeneous nuclear ribonucleoprotein h2. it is characterized by delayed psychomotor development, intellectual disability with behavioral abnormalities, and dysmorphic facial features in females.

• Neurodevelopmental Disorder

  a childhood disorder that has a neurological basis and manifests as a developmental disability.

• Neurodevelopmental Disorder with Brain Abnormalities, Poor Growth, and Dysmorphic Facies|Intellectual Disability-Strabismus Syndrome|NEDBGF

  an autosomal recessive disorder caused by mutation(s) in the adat3 gene, encoding probable inactive trna-specific adenosine deaminase-like protein 3. it is characterized by a neurodevelopmental disorder with brain abnormalities, poor growth, and abnormal facies.

• Neurodevelopmental Disorder with Severe Motor Impairment, Absent Language, Cerebral Hypomyelination, and Brain Atrophy|NEDMLHB

  an autosomal recessive condition caused by mutations(s) in the taf8 gene, encoding transcription initiation factor tfiid subunit 8. it is characterized by severe motor impairment, absent language, cerebral hypomyelination, and brain atrophy.

• Neurodevelopmental Disorder with Spastic Diplegia and Visual Defects|MRD19|Mental Retardation, Autosomal Dominant 19|NEDSDV

  an autosomal dominant condition caused by mutation(s) in the ctnnb1 gene, encoding catenin beta-1. it is characterized by severe intellectual disability, progressive spastic diplegia, visual impairment, and dysmorphic craniofacial features.

• Pervasive Developmental Disorder

  a category of developmental disorders characterized by impaired communication and socialization skills. the impairments are incongruent with the individual's developmental level or mental age. these disorders can be associated with general medical or genetic conditions.

• Acute Motor and Sensory Axonal Neuropathy|Acute Motor And Sensory Axonal Neuropathy|Acute Motor-Sensory Axonal Neuropathy|Acute Motor-Sensory Axonal Neuropathy

  a subtype of guillain-barre syndrome that targets sensory motor axons, and is characterized by acute onset of quadriparesis, distal sensory loss, areflexia, and respiratory insufficiency.

• Acute Motor Axonal Neuropathy|AMAN

  a subtype of guillain-barre syndrome that targets motor axons, and is characterized by symmetric limb weakness, diffuse areflexia, facial and oropharyngeal muscle weakness, and respiratory insufficiency.

• Axonal Neuropathy

  any nerve disorder affecting the axon of a nerve.

• GAN wt Allele|GAN1|Giant Axonal Neuropathy (Gigaxonin) Gene|Gigaxonin wt Allele|KLHL16

  human gan wild-type allele is located in the vicinity of 16q24.1 and is approximately 65 kb in length. this allele, which encodes gigaxonin protein, is involved in both ubiquitination and neurofilament structure. mutation of the gene is associated with giant axonal neuropathy.

• Giant Axonal Neuropathy

  a rare inherited disorder affecting the neurofilaments. it is caused by mutations in the gan gene. it is characterized by the presence of abnormally large nerve cell axons. signs and symptoms include difficulty walking, sensory disturbances, lack of motor coordination and abnormal reflexes in the limbs.

• Spinocerebellar Ataxia, Autosomal Recessive, with Axonal Neuropathy 2|AOA2|Ataxia with Oculomotor Apraxia Type 2|SCAN2

  an autosomal recessive condition caused by mutation(s) in the setx gene, encoding probable helicase senataxin. it is characterized by juvenile onset progressive cerebellar ataxia, axonal sensorimotor peripheral neuropathy, and increased concentrations of serum alpha-fetoprotein. oculomotor apraxia is common, but is not always present.

• Cortical Blindness

  visual impairment due to visual cortex dysfunction.

• Homeostatic Model Assessment of Insulin Resistance

  an assessment of beta-cell function and insulin resistance based on fasting blood glucose and insulin concentrations.

• Insulin Receptor Mutation - Associated Insulin Resistance Syndromes

  insulin resistance caused by inactivating mutation(s) in the insr gene encoding the insulin receptor.

• Insulin Resistance

  decreased sensitivity to circulating insulin which may result in acanthosis nigicrans, elevated insulin level or hyperglycemia.

• Insulin Resistance Measurement|INSULINR|Insulin Resistance|Insulin Resistance

  the determination of the insulin resistance (cells inability to respond to insulin) in a biological specimen.

• Insulin Resistance Syndrome

  a cluster of closely related metabolic abnormalities associated with insulin resistance that confer an increased risk of the development of type 2 diabetes and cardiovascular disease. these abnormalities may include obesity, high blood pressure, abnormal cholesterol levels, proteinuria, and/or polycystic ovary syndrome.

• Obesity-Associated Insulin Resistance

  insulin resistance associated with obesity, which may be attributed in part to impaired insulin signaling in target tissues, or impaired insulin-stimulated glucose transport due to reduced expression of the glucose transporter protein 4.

• Achondroplasia

  an autosomal dominant disorder caused by mutation(s) in the fgfr3 gene, encoding fibroblast growth factor receptor 3. the condition is characterized by inappropriate cartilage growth plate differentiation and deficient endochondral growth, manifest clinically with severe rhizomelic short stature, short limbs, characteristic facies with frontal bossing and midface hypoplasia.

• COMP wt Allele|Cartilage Oligomeric Matrix Protein (Pseudoachondroplasia, Epiphyseal Dysplasia 1, Multiple) Gene|Cartilage Oligomeric Matrix Protein wt Allele|Cartilage Oligomeric Matrix Protein(Pseudoachondroplasia, Epiphyseal Dysplasia 1, Multiple) Gene|EDM1|EPD1|MED|PSACH|Pseudoachondroplasia (Epiphyseal Dysplasia 1, Multiple) Gene|THBS5

  human comp wild-type allele is located in the vicinity of 19p13.1 and is approximately 9 kb in length. this allele, which encodes cartilage oligomeric matrix protein, is involved in cartilage structural integrity. mutation of the gene is associated with pseudoachondroplasia and multiple epiphyseal dysplasia 1.

• FGFR3 wt Allele|ACH|Achondroplasia, Thanatophoric Dwarfism Gene|CD333|CEK2|FGFR3|Fibroblast Growth Factor Receptor 3 (Achondroplasia, Thanatophoric Dwarfism) Gene|Fibroblast Growth Factor Receptor 3 wt Allele|HSFGFR3EX|JTK4

  human fgfr3 wild-type allele is located in the vicinity of 4p16.3 and is approximately 15 kb in length. this allele, which encodes fibroblast growth factor receptor 3 protein, is involved in mitogenesis, differentiation, and bone development and maintenance. alterations in the gene resulting in defects cause, achondroplasia, crouzon syndrome, thanatophoric dysplasia, coronal synostosis, hypochondroplasia, bladder and cervix cancers.

• Pseudoachondroplasia

  a rare, autosomal dominant inherited disorder caused by mutations in the comp gene. it is characterized by short stature, short arms and legs, waddling walk, osteoarthritis, and limited range of motion at the elbows and hips.

• Intellectual Developmental Disorder, Autosomal Dominant 52|MRD52|Mental Retardation, Autosomal Dominant 52

  an autosomal dominant subtype of intellectual developmental disorder caused by mutation(s) in the ash1l gene, encoding histone-lysine n-methyltransferase ash1l.

• Intellectual Developmental Disorder, X-Linked, Syndromic, Nascimento Type|MRXSN

  an x-linked recessive condition caused by mutation(s) in the ube2a gene, encoding ubiquitin-conjugating enzyme e2 a. it is characterized by facial dysmorphisms and intellectual impairment.

• Neurodevelopmental Disorder with or without Autistic Features and/or Structural Brain Abnormalities|NEDASB

  an autosomal dominant condition caused by mutation(s) in the nova2 gene, encoding rna-binding protein nova-2. it is characterized by global developmental delay, impaired speech development, and behavioral characteristics of autism.

• Neurodevelopmental Disorder with or without Hyperkinetic Movements and Seizures, Autosomal Dominant|NDHMSD

  an autosomal dominant condition caused by mutation(s) in the grin1 gene, encoding glutamate receptor ionotropic, nmda 1. it is characterized by developmental delay, intellectual disability and may include epilepsy and associated muscular disorders.

• Neurodevelopmental Disorder with or without Variable Brain Abnormalities|NEDBA

  an autosomal dominant condition caused by mutation(s) in the mapk8ip3 gene, encoding c-jun-amino-terminal kinase-interacting protein 3. it is commonly characterized by global developmental delay, intellectual disability, and spastic diplegia. there may be associated brain abnormalities include cerebellar and/or cerebral atrophy, and hypoplasia of the corpus callosum.

• X-Linked Syndromic Intellectual Developmental Disorder with Pigmentary Mosaicism and Coarse Facies|MRXSPF

  an x-linked condition caused by mutation(s) in the tfe3 gene, encoding transcription factor e3. it is characterized by a triad of developmental delay, blaschkoid pigmentary mosaicism, and characteristic coarse facial features.

Convert F89 to ICD-9-CM

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

Patient Education

Developmental Disabilities

Developmental disabilities are severe, long-term problems. They may be physical, such as blindness. They may affect mental ability, such as learning disabilities. Or the problem can be both physical and mental, such as Down syndrome. The problems are usually life-long, and can affect everyday living.

There are many causes of developmental disabilities, including:

• Genetic or chromosome abnormalities. These cause conditions such as Down syndrome and Rett syndrome.
• Prenatal exposure to substances. For example, drinking alcohol when pregnant can cause fetal alcohol spectrum disorders.
• Certain infections in pregnancy
• Preterm birth

Often there is no cure, but treatment can help the symptoms. Treatments include physical, speech, and occupational therapy. Special education classes and psychological counseling can also help.

NIH: National Institute of Child Health and Human Development

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.