2026 ICD-10-CM Diagnosis Code QA0.0142DLG4-related synaptopathy

ICD-10-CM Codes›Q00-Q99›Q90-Q99›QA0

ICD-10-CM QA0.0142
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

QA0.0142 is a billable ICD-10-CM diagnosis code for DLG4-related synaptopathy. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. The code is exempt from POA reporting.

Code Identity

ICD-10-CM Code
QA0.0142
Billable Status
Yes — Valid for Submission
Code Describes
DLG4-related synaptopathy
Short Description
DLG4-related synaptopathy
Same as the full description in the CMS dataset.
Parent Code
QA0.014
Neurodevelopmental disorders, related to pathogenic variants in synapse related genes

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ90-Q99Chromosomal abnormalities, not elsewhere classified
CategoryQA0Neurodevelopmental disorders related to specific genetic pathogenic variants
This CodeQA0.0142DLG4-related synaptopathy

Present on Admission (POA)Billing

QA0.0142 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • neurodevelopmental
        • DLG4-related synaptopathy
    • Synaptopathy
      • DLG4-related

Code History & ChangesHistory

New Code QA0.0142 was added to the ICD-10-CM code set for FY 2026, effective October 1, 2025.

Replacement QA0.0142 replaces the following previously assigned code(s):

  • F89 - Unspecified disorder of psychological development
FY 2026AddedAdded to the ICD-10-CM code setEffective October 1, 2025.
FY 2026CurrentRevised in the current code setEffective October 1, 2025 through September 30, 2026.

Questions About QA0.0142Overview

Is QA0.0142 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report DLG4-related synaptopathy on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does QA0.0142 group to?

When DLG4-related synaptopathy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.

Is QA0.0142 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for DLG4-related synaptopathy on inpatient claims.