2027 ICD-10-CM Diagnosis Code O88.111Amniotic fluid embolism in pregnancy, first trimester
ICD-10-CM Codes›O00-O9A›O85-O92›O88
- Billable — Valid for Submission
- MCC — Major Complication or Comorbidity
- Not Chronic
O88.111 is a billable ICD-10-CM diagnosis code for amniotic fluid embolism in pregnancy, first trimester. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 817 through 819, 831 through 833. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 250 closely related codes. The code is restricted by the Medicare Code Editor to maternity cases (age 9 through 64). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified complications in pregnancy.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for O88.111.
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to O88.111: its own notes plus those printed at O88, block O85-O92, and Chapter 15. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- supervision of normal pregnancy (Z34.-)
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code, if applicable, from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known.
Notes
General instructions on how these codes are used.
- CODES FROM THIS CHAPTER ARE FOR USE ONLY ON MATERNAL RECORDS, NEVER ON NEWBORN RECORDS
- Codes from this chapter are for use for conditions related to or aggravated by the pregnancy, childbirth, or by the puerperium (maternal causes or obstetric causes)
- Trimesters are counted from the first day of the last menstrual period. They are defined as follows:
- 1st trimester- less than 14 weeks 0 days
- 2nd trimester- 14 weeks 0 days to less than 28 weeks 0 days
- 3rd trimester- 28 weeks 0 days until delivery
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name O88.111, its category, or a range that includes it.
Excludes1 1
These codes carry an Excludes1 note naming O88.111: they are not reported together with it, unless the two conditions are unrelated.
Excludes2 4
These codes carry an Excludes2 note naming O88.111: its condition is not part of those codes, and both may be reported when the patient has both.
- I26 Pulmonary embolismpulmonary embolism complicating pregnancy, childbirth and the puerperium (O88.-) names O88.-, which includes this code
- O22 Venous complications and hemorrhoids in pregnancyobstetric pulmonary embolism (O88.-) names O88.-, which includes this code
- O87 Venous complications and hemorrhoids in the puerperiumobstetric embolism (O88.-) names O88.-, which includes this code
- O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperiumobstetric embolism (O88.-) names O88.-, which includes this code
Code First 1
These codes say to code first a condition named in the note, and O88.111 is one of the conditions named.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Embolism, Amniotic Fluid
blocking of maternal circulation by amniotic fluid that is forced into uterine veins by strong uterine contraction near the end of pregnancy. it is characterized by the sudden onset of severe respiratory distress and hypotension that can lead to maternal death.
Patient EducationClinical
Health Problems in Pregnancy
A health problem in pregnancy is any disease or condition that could affect your health or the health of your fetus. Some health problems may make it more likely that you will have a high-risk pregnancy. A high-risk pregnancy is one in which you, your fetus, or both are at higher risk for health problems than in a typical pregnancy.
The full article covers:
- What are health problems in pregnancy?
- What raises my risk for health problems during pregnancy?
- Can chronic health conditions cause problems in pregnancy?
- Can health problems in pregnancy be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert O88.111 to ICD-9-CMHistory
Code HistoryHistory
Questions About O88.111Overview
What is the ICD-10 code for amniotic fluid embolism in pregnancy, first trimester?
The ICD-10-CM code for amniotic fluid embolism in pregnancy, first trimester is O88.111 (sometimes written as O88111). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is O88.111 (Amniotic fluid embolism in pregnancy) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report amniotic fluid embolism in pregnancy, first trimester on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does O88.111 group to?
When amniotic fluid embolism in pregnancy, first trimester is the principal diagnosis on an inpatient stay, it groups to MS-DRG 833, 832, 831, 819, 818, 817, with relative weights from 0.5000 to 1.7586 depending on complications. Higher weights mean higher Medicare reimbursement.
Is O88.111 a CC or MCC?
CMS lists O88.111 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 250 closely related codes in its exclusion list.
Who can O88.111 be reported for?
The Medicare Code Editor checks amniotic fluid embolism in pregnancy, first trimester against patient demographics: this code is intended for maternity cases (age 9 through 64). Claims outside these limits are flagged as inconsistent.
