2026 ICD-10-CM Diagnosis Code O45.8X1Other premature separation of placenta, first trimester

ICD-10-CM Codes›O00-O9A›O30-O48›O45

ICD-10-CM O45.8X1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

O45.8X1 is a billable ICD-10-CM diagnosis code for other premature separation of placenta, first trimester. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 817 through 819, 831 through 833. The code is restricted by the Medicare Code Editor to maternity cases (age 9 through 64). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Early, first or unspecified trimester hemorrhage; and Maternal care related to disorders of the placenta and placental implantation.

Code Identity

ICD-10-CM Code
O45.8X1
Billable Status
Yes — Valid for Submission
Code Describes
Other premature separation of placenta, first trimester
Short Description
Other premature separation of placenta, first trimester
Same as the full description in the CMS dataset.
Parent Code
O45.8X
Other premature separation of placenta

Code Classification

ChapterO00-O9APregnancy, childbirth and the puerperium
SectionO30-O48Maternal care related to the fetus and amniotic cavity and possible delivery problems
CategoryO45Premature separation of placenta [abruptio placentae]
This CodeO45.8X1Other premature separation of placenta, first trimester

Code EditsBilling

Medicare Code Editor checks that affect claim validity for O45.8X1.

Maternity diagnoses
The Medicare Code Editor detects inconsistencies in maternity cases by checking a patient's age and any diagnosis on the patient's record. The maternity code edits apply to patients age ange is 9–64 years inclusive (e.g., diabetes in pregnancy, antepartum pulmonary complication).

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PRG009
Early, first or unspecified trimester hemorrhage
Default principal diagnosis: inpatient No · outpatient No
CCSR PRG018
Maternal care related to disorders of the placenta and placental implantation
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Childbirth Problems

Childbirth is the process of giving birth to a baby. It includes labor and delivery. Usually everything goes well, but problems can happen. They may cause a risk to the mother, baby, or both. Some of the more common childbirth problems include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert O45.8X1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
641.21 Prem separ placen-deliv
Approximate The match is approximate rather than exact.
ICD-9-CM
641.23 Prem separ plac-antepart
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About O45.8X1Overview

Is O45.8X1 (Other premature separation of placenta) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other premature separation of placenta, first trimester on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does O45.8X1 group to?

When other premature separation of placenta, first trimester is the principal diagnosis on an inpatient stay, it groups to MS-DRG 817, 818, 819, 831, 832, 833, with relative weights from 0.5229 to 1.6880 depending on complications. Higher weights mean higher Medicare reimbursement.

Who can O45.8X1 be reported for?

The Medicare Code Editor checks other premature separation of placenta, first trimester against patient demographics: this code is intended for maternity cases (age 9 through 64). Claims outside these limits are flagged as inconsistent.

What is the ICD-9 equivalent of O45.8X1?

Under the General Equivalence Mappings, other premature separation of placenta, first trimester converts to ICD-9-CM 641.21 (prem separ placen-deliv) and 641.23 (prem separ plac-antepart). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.