2027 ICD-10-CM Diagnosis Code O12.25Gestational edema with proteinuria, complicating the puerperium

ICD-10-CM Codes›O00-O9A›O10-O16›O12

ICD-10-CM O12.25
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

O12.25 is a billable ICD-10-CM diagnosis code for gestational edema with proteinuria, complicating the puerperium. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 769, 776. The code is restricted by the Medicare Code Editor to maternity cases (age 9 through 64). Coders also document this condition as gestational edema. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Complications specified during the puerperium and Proteinuria.

Code Identity

ICD-10-CM Code
O12.25
Billable Status
Yes — Valid for Submission
Code Describes
Gestational edema with proteinuria, complicating the puerperium
Short Description
Gestational edema with proteinuria, comp the puerperium
Parent Code
Gestational edema with proteinuria

Code Classification

ChapterO00-O9APregnancy, childbirth and the puerperium
SectionO10-O16Edema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
CategoryO12Gestational [pregnancy-induced] edema and proteinuria without hypertension
This CodeO12.25Gestational edema with proteinuria, complicating the puerperium

Code EditsBilling

Medicare Code Editor checks that affect claim validity for O12.25.

The Medicare Code Editor detects inconsistencies in maternity cases by checking a patient's age and any diagnosis on the patient's record. The maternity code edits apply to patients age ange is 9–64 years inclusive (e.g., diabetes in pregnancy, antepartum pulmonary complication).

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Gestational edema
  • Gestational edema with proteinuria
  • Gestational edema with proteinuria during maternal postpartum period
  • Gestational proteinuria
  • Postpartum edema
  • Postpartum gestational proteinuria

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to O12.25: its own notes plus those printed at Chapter 15. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • supervision of normal pregnancy (Z34.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • mental and behavioral disorders associated with the puerperium (F53.-)
  • obstetrical tetanus (A34)
  • postpartum necrosis of pituitary gland (E23.0)
  • puerperal osteomalacia (M83.0)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • code, if applicable, from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known.

Notes

General instructions on how these codes are used.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • CODES FROM THIS CHAPTER ARE FOR USE ONLY ON MATERNAL RECORDS, NEVER ON NEWBORN RECORDS
  • Codes from this chapter are for use for conditions related to or aggravated by the pregnancy, childbirth, or by the puerperium (maternal causes or obstetric causes)
  • Trimesters are counted from the first day of the last menstrual period. They are defined as follows:
  • 1st trimester- less than 14 weeks 0 days
  • 2nd trimester- 14 weeks 0 days to less than 28 weeks 0 days
  • 3rd trimester- 28 weeks 0 days until delivery

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name O12.25, its category, or a range that includes it.

Includes 1

These notes mention O12.25.

  • O15 Eclampsia
    convulsions following conditions in O10-O14 and O16 names O10-O14, which includes this code

Excludes2 2

These codes carry an Excludes2 note naming O12.25: its condition is not part of those codes, and both may be reported when the patient has both.

  • O26.0 Excessive weight gain in pregnancy
    gestational edema (O12.0, O12.2) names O12.2, which includes this code
  • O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
    hypertensive disorders (O10-O16) names O10-O16, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PRG027
Complications specified during the puerperium
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR GEN010
Proteinuria
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Childbirth Problems

Childbirth is the process of giving birth to a baby. It includes labor and delivery. Usually everything goes well, but problems can happen. They may cause a risk to the mother, baby, or both. Some of the more common childbirth problems include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert O12.25 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
646.14 Edema in preg-postpartum
Approximate The match is approximate rather than exact.
ICD-9-CM
646.14 Edema in preg-postpartum
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
646.24 Renal dis NOS-postpartum
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
646.12 Edema in preg-del w p/p
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
646.22 Renal dis NOS-del w p/p
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code History & ChangesHistory

Replacement O12.25 replaces the following previously assigned code(s):

  • O12.20 - Gestational edema with proteinuria, unspecified trimester
FY 2019AddedAdded to the ICD-10-CM code setEffective October 1, 2018.
FY 2020–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About O12.25Overview

What is the ICD-10 code for gestational edema with proteinuria, complicating the puerperium?

The ICD-10-CM code for gestational edema with proteinuria, complicating the puerperium is O12.25 (sometimes written as O1225). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is O12.25 (Gestational edema with proteinuria) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report gestational edema with proteinuria, complicating the puerperium on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does O12.25 group to?

When gestational edema with proteinuria, complicating the puerperium is the principal diagnosis on an inpatient stay, it groups to MS-DRG 769, 776, with relative weights from 0.6718 to 1.6666 depending on complications. Higher weights mean higher Medicare reimbursement.

Who can O12.25 be reported for?

The Medicare Code Editor checks gestational edema with proteinuria, complicating the puerperium against patient demographics: this code is intended for maternity cases (age 9 through 64). Claims outside these limits are flagged as inconsistent.

What is the ICD-9 equivalent of O12.25?

Under the General Equivalence Mappings, gestational edema with proteinuria, complicating the puerperium converts to ICD-9-CM 646.14 (edema in preg-postpartum), 646.14 (edema in preg-postpartum), and 646.24 (renal dis NOS-postpartum). The mapping is approximate, so confirm the match fits the documentation.