2026 ICD-10-CM Diagnosis Code O12.25Gestational edema with proteinuria, complicating the puerperium

ICD-10-CM Codes›O00-O9A›O10-O16›O12

ICD-10-CM O12.25
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

O12.25 is a billable ICD-10-CM diagnosis code for gestational edema with proteinuria, complicating the puerperium. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is restricted by the Medicare Code Editor to maternity cases (age 9 through 64). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Complications specified during the puerperium and Proteinuria.

Code Identity

ICD-10-CM Code
O12.25
Billable Status
Yes — Valid for Submission
Code Describes
Gestational edema with proteinuria, complicating the puerperium
Short Description
Gestational edema with proteinuria, comp the puerperium
Parent Code
O12.2
Gestational edema with proteinuria

Code Classification

ChapterO00-O9APregnancy, childbirth and the puerperium
SectionO10-O16Edema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
CategoryO12Gestational [pregnancy-induced] edema and proteinuria without hypertension
This CodeO12.25Gestational edema with proteinuria, complicating the puerperium

Code EditsBilling

Medicare Code Editor checks that affect claim validity for O12.25.

Maternity diagnoses
The Medicare Code Editor detects inconsistencies in maternity cases by checking a patient's age and any diagnosis on the patient's record. The maternity code edits apply to patients age ange is 9–64 years inclusive (e.g., diabetes in pregnancy, antepartum pulmonary complication).

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Puerperal, puerperium(complicated by, complications)
      • gestational
        • edema
          • with proteinuria

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PRG027
Complications specified during the puerperium
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR GEN010
Proteinuria
Default principal diagnosis: inpatient No · outpatient No

Convert O12.25 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
646.14 Edema in preg-postpartum
Approximate The match is approximate rather than exact.
ICD-9-CM
646.14 Edema in preg-postpartum
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
646.24 Renal dis NOS-postpartum
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
646.12 Edema in preg-del w p/p
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
646.22 Renal dis NOS-del w p/p
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code History & ChangesHistory

Replacement O12.25 replaces the following previously assigned code(s):

  • O12.20 - Gestational edema with proteinuria, unspecified trimester
FY 2018AddedAdded to the ICD-10-CM code setEffective October 1, 2017.
FY 2019–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About O12.25Overview

Is O12.25 (Gestational edema with proteinuria) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report gestational edema with proteinuria, complicating the puerperium on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Who can O12.25 be reported for?

The Medicare Code Editor checks gestational edema with proteinuria, complicating the puerperium against patient demographics: this code is intended for maternity cases (age 9 through 64). Claims outside these limits are flagged as inconsistent.

What is the ICD-9 equivalent of O12.25?

Under the General Equivalence Mappings, gestational edema with proteinuria, complicating the puerperium converts to ICD-9-CM 646.14 (edema in preg-postpartum), 646.14 (edema in preg-postpartum), and 646.24 (renal dis NOS-postpartum). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.