2026 ICD-10-CM Diagnosis Code F43.89Other reactions to severe stress

ICD-10-CM Codes›F01–F99›F40-F48›F43

ICD-10-CM F43.89
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

F43.89 is a billable ICD-10-CM diagnosis code for other reactions to severe stress. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as caregiver stress syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Trauma- and stressor-related disorders.

Code Identity

ICD-10-CM Code
F43.89
Billable Status
Yes — Valid for Submission
Code Describes
Other reactions to severe stress
Short Description
Other reactions to severe stress
Same as the full description in the CMS dataset.
Parent Code
F43.8
Other reactions to severe stress

Code Classification

ChapterF01–F99Mental and behavioural disorders
SectionF40-F48Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders
CategoryF43Reaction to severe stress, and adjustment disorders
This CodeF43.89Other reactions to severe stress

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Caregiver stress syndrome
  • Muscle tension
  • Stress and adjustment reaction
  • Stress-induced muscle tension

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • trauma and stressor-related NOS
        • other specified
    • Reaction
      • stress (severe)
        • specified NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MBD007
Trauma- and stressor-related disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Stress

Stress is how your brain and body respond to a challenge or demand. When you are stressed, your body releases certain hormones. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work. The hormones that are released when you are stressed make you alert and ready to act.

The full article covers:

  • What is stress?
  • What causes long-term stress?
  • How can long term-stress harm my health?
  • How can I manage long-term stress?
  • When should I ask my health care provider for help with stress?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement F43.89 replaces the following previously assigned code(s):

  • F43.8 - Other reactions to severe stress
FY 2023AddedAdded to the ICD-10-CM code setEffective October 1, 2022.
FY 2024–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About F43.89Overview

Is F43.89 (Other reactions to severe stress) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other reactions to severe stress on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.