2026 ICD-10-CM Diagnosis Code F16.259Hallucinogen dependence with hallucinogen-induced psychotic disorder, unspecified

ICD-10-CM Codes›F01–F99›F10-F19›F16

ICD-10-CM F16.259
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

F16.259 is a billable ICD-10-CM diagnosis code for hallucinogen dependence with hallucinogen-induced psychotic disorder, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 894 through 897. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hallucinogen-related disorders and Schizophrenia spectrum and other psychotic disorders.

Code Identity

ICD-10-CM Code
F16.259
Billable Status
Yes — Valid for Submission
Code Describes
Hallucinogen dependence with hallucinogen-induced psychotic disorder, unspecified
Short Description
Hallucinogen dependence w psychotic disorder, unsp
Parent Code
F16.25
Hallucinogen dependence with hallucinogen-induced psychotic disorder

Code Classification

ChapterF01–F99Mental and behavioural disorders
SectionF10-F19Mental and behavioral disorders due to psychoactive substance use
CategoryF16Hallucinogen related disorders
This CodeF16.259Hallucinogen dependence with hallucinogen-induced psychotic disorder, unspecified

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Dependence(on) (syndrome)
      • drug NEC
        • hallucinogen
          • with
            • psychosis
    • Disorder(of)
      • hallucinogen use
        • moderate or severe
          • with
            • hallucinogen-induced
              • psychotic disorder
    • Disorder(of)
      • phencyclidine use
        • moderate or severe
          • with
            • phencyclidine-induced
              • psychotic disorder

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MBD022
Hallucinogen-related disorders
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR MBD001
Schizophrenia spectrum and other psychotic disorders
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Drug Use and Addiction

Drugs are chemical substances that can change how your body and mind work. They include prescription medicines, over-the-counter medicines, alcohol, tobacco, and illegal drugs.

The full article covers:

  • What are drugs?
  • What is drug use?
  • What is drug addiction?
  • Does everyone who takes drugs become addicted?
  • Who is at risk for drug addiction?
  • What are the signs that someone has a drug problem?
  • What are the treatments for drug addiction?
  • Can drug use and addiction be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert F16.259 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
292.89 Drug mental disorder NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
304.50 Hallucinogen dep-unspec
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About F16.259Overview

Is F16.259 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hallucinogen dependence with hallucinogen-induced psychotic disorder, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does F16.259 group to?

When hallucinogen dependence with hallucinogen-induced psychotic disorder, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 894, 895, 896, 897, with relative weights from 0.6169 to 1.7451 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of F16.259?

Under the General Equivalence Mappings, hallucinogen dependence with hallucinogen-induced psychotic disorder, unspecified converts to ICD-9-CM 292.89 (drug mental disorder NEC) and 304.50 (hallucinogen dep-unspec). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.