2026 ICD-10-CM Diagnosis Code F12.280Cannabis dependence with cannabis-induced anxiety disorder

ICD-10-CM Codes›F01–F99›F10-F19›F12

ICD-10-CM F12.280
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

F12.280 is a billable ICD-10-CM diagnosis code for cannabis dependence with cannabis-induced anxiety disorder. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 894 through 897. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Anxiety and fear-related disorders and Cannabis-related disorders.

Code Identity

ICD-10-CM Code
F12.280
Billable Status
Yes — Valid for Submission
Code Describes
Cannabis dependence with cannabis-induced anxiety disorder
Short Description
Cannabis dependence with cannabis-induced anxiety disorder
Same as the full description in the CMS dataset.
Parent Code
F12.28
Cannabis dependence with other cannabis-induced disorder

Code Classification

ChapterF01–F99Mental and behavioural disorders
SectionF10-F19Mental and behavioral disorders due to psychoactive substance use
CategoryF12Cannabis related disorders
This CodeF12.280Cannabis dependence with cannabis-induced anxiety disorder

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Dependence(on) (syndrome)
      • drug NEC
        • cannabis
          • with
            • anxiety disorder
    • Disorder(of)
      • anxiety
        • due to (secondary to)
          • cannabis
            • in
              • dependence
    • Disorder(of)
      • cannabis use
        • moderate or severe
          • with
            • cannabis-induced
              • anxiety disorder

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MBD005
Anxiety and fear-related disorders
Default principal diagnosis: inpatient No · outpatient No
CCSR MBD019
Cannabis-related disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Anxiety

Anxiety is a feeling of fear, dread, and uneasiness. It might cause you to sweat, feel restless and tense, and have a rapid heartbeat. It can be a normal reaction to stress. For example, you might feel anxious when faced with a difficult problem at work, before taking a test, or before making an important decision.

The full article covers:

  • What is anxiety?
  • What are anxiety disorders?
  • What are the types of anxiety disorders?
  • What causes anxiety disorders?
  • Who is at risk for anxiety disorders?
  • What are the symptoms of anxiety disorders?
  • How are anxiety disorders diagnosed?
  • What are the treatments for anxiety disorders?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert F12.280 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
292.89 Drug mental disorder NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
304.30 Cannabis depend-unspec
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About F12.280Overview

Is F12.280 (Cannabis dependence with other cannabis-induced disorder) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report cannabis dependence with cannabis-induced anxiety disorder on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does F12.280 group to?

When cannabis dependence with cannabis-induced anxiety disorder is the principal diagnosis on an inpatient stay, it groups to MS-DRG 894, 895, 896, 897, with relative weights from 0.6169 to 1.7451 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of F12.280?

Under the General Equivalence Mappings, cannabis dependence with cannabis-induced anxiety disorder converts to ICD-9-CM 292.89 (drug mental disorder NEC) and 304.30 (cannabis depend-unspec). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.