2026 ICD-10-CM Diagnosis Code E05.01Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm

ICD-10-CM CodesE00–E89E00-E07E05

ICD-10-CM E05.01
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E05.01 is a billable ICD-10-CM diagnosis code for thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Thyroid disorders.

Code Identity

ICD-10-CM Code
E05.01
Billable Status
Yes — Valid for Submission
Code Describes
Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm
Short Description
Thyrotoxicosis w diffuse goiter w thyrotoxic crisis or storm
Parent Code
Thyrotoxicosis with diffuse goiter

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE00-E07Disorders of thyroid gland
CategoryE05Thyrotoxicosis [hyperthyroidism]
This CodeE05.01Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Graves' disease
  • Graves' disease with acropachy AND with thyrotoxic crisis
  • Graves' disease with pretibial myxedema AND with thyrotoxic crisis
  • Hypertrophic osteoarthropathy
  • Pretibial myxedema
  • Thyroid acropachy
  • Thyroid-associated dermopathy
  • Thyrotoxic crisis
  • Thyrotoxicosis due to Graves' disease
  • Toxic diffuse goiter
  • Toxic diffuse goiter with acropachy
  • Toxic diffuse goiter with crisis
  • Toxic diffuse goiter with pretibial myxedema
  • Toxic diffuse goiter with thyrotoxic crisis

Index to Diseases and InjuriesGuidance

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Hyperthyroidism(latent) (pre-adult) (recurrent)
      • with
        • goiter (diffuse)
          • with thyroid storm
    • Marsh's disease(exophthalmic goiter)
      • with storm
    • Ophthalmoplegia
      • exophthalmic
        • with thyroid storm
    • Parry's disease or syndrome
      • with thyroid storm
    • Parson's disease(exophthalmic goiter)
      • with thyroid storm
    • Stokes' disease
      • with thyroid storm
    • Syndrome
      • Basedow's
        • with thyroid storm
    • Syndrome
      • Flajani (-Basedow)
        • with thyroid storm
    • Syndrome
      • Parry's
        • with thyroid storm
    • Thyrotoxicosis(recurrent)
      • with
        • goiter (diffuse)
          • with thyroid storm
    • Thyrotoxicosis(recurrent)
      • with
        • infiltrative
          • dermopathy
            • with thyroid storm
    • Thyrotoxicosis(recurrent)
      • with
        • infiltrative
          • ophthalmopathy
            • with thyroid storm

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END001
Thyroid disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Hyperthyroidism

Hyperthyroidism, or overactive thyroid, happens when your thyroid gland makes more thyroid hormones than your body needs.

The full article covers:

  • What is hyperthyroidism?
  • What causes hyperthyroidism?
  • Who is at risk for hyperthyroidism?
  • What are the symptoms of hyperthyroidism?
  • What other problems can hyperthyroidism cause?
  • How is hyperthyroidism diagnosed?
  • What are the treatments for hyperthyroidism?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E05.01 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
242.01 Tox dif goiter w crisis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E05.01Overview

Is E05.01 (Thyrotoxicosis with diffuse goiter) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E05.01 group to?

When thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E05.01?

Under the General Equivalence Mappings, thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm converts to ICD-9-CM 242.01 (tox dif goiter w crisis). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.