2026 ICD-10-CM Diagnosis Code D16.4Benign neoplasm of bones of skull and face

ICD-10-CM CodesC00–D49D10-D36D16

ICD-10-CM D16.4
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D16.4 is a billable ICD-10-CM diagnosis code for benign neoplasm of bones of skull and face. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.

Code Identity

ICD-10-CM Code
D16.4
Billable Status
Yes — Valid for Submission
Code Describes
Benign neoplasm of bones of skull and face
Short Description
Benign neoplasm of bones of skull and face
Same as the full description in the CMS dataset.
Parent Code
Benign neoplasm of bone and articular cartilage

Code Classification

ChapterC00–D49Neoplasms
SectionD10-D36Benign neoplasms, except benign neuroendocrine tumors
CategoryD16Benign neoplasm of bone and articular cartilage
This CodeD16.4Benign neoplasm of bones of skull and face

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Benign glomus tumor
  • Benign glomus tumor of mastoid
  • Benign neoplasm of accessory sinus
  • Benign neoplasm of articular cartilage
  • Benign neoplasm of bone of skull
  • Benign neoplasm of cheek
  • Benign neoplasm of ethmoid bone
  • Benign neoplasm of face bone
  • Benign neoplasm of frontal bone
  • Benign neoplasm of hard palate
  • Benign neoplasm of lacrimal bone
  • Benign neoplasm of maxilla
  • Benign neoplasm of middle ear and mastoid
  • Benign neoplasm of nasal bone
  • Benign neoplasm of nasal skeleton
  • Benign neoplasm of occipital bone
  • Benign neoplasm of palate
  • Benign neoplasm of palatine bone
  • Benign neoplasm of parietal bone
  • Benign neoplasm of sella turcica
  • Benign neoplasm of septum of nose
  • Benign neoplasm of skull and facial bones
  • Benign neoplasm of sphenoid bone
  • Benign neoplasm of temporal bone
  • Benign neoplasm of vomer
  • Benign neoplasm of zygomatic bone
  • Benign odontogenic tumor of upper jaw
  • Benign osteogenic neoplasm of articular cartilage of head
  • Benign osteogenic neoplasm of bone of head
  • Dermoid cyst of frontonasal region
  • Dermoid cyst of skull
  • Disorder of lacrimal bone
  • External auditory canal osteoma
  • Fibromyxoma of maxilla
  • Mass of parietal bone of skull
  • Melanotic neuroectodermal tumor of maxilla
  • Nasal sinus osteoma
  • Neoplasm of ethmoid bone
  • Neoplasm of frontal bone
  • Neoplasm of nasal bone
  • Neoplasm of occipital bone
  • Neoplasm of palatine bone
  • Neoplasm of parietal bone
  • Neoplasm of sphenoid bone
  • Neoplasm of vomer
  • Neoplasm of zygomatic bone
  • Odontoma of upper jaw
  • Osteoma
  • Osteoma of face
  • Osteoma of orbit
  • Osteoma of skull
  • Temporal odontoma

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Benign neoplasm of maxilla (superior)
  • Benign neoplasm of orbital bone
  • Keratocyst of maxilla
  • Keratocystic odontogenic tumor of maxilla

Type 2 Excludes

  • benign neoplasm of lower jaw bone D16.5

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Cyst(colloid) (mucous) (simple) (retention)
      • calcifying odontogenic
        • upper jaw (bone) (maxilla)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO073
Benign neoplasms
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Osteoblastoma

    a benign, painful, tumor of bone characterized by the formation of osteoid tissue, primitive bone and calcified tissue. it occurs frequently in the spine of young persons. (from dorland, 27th ed; stedman, 25th ed)
  • Osteoma

    a benign tumor composed of bone tissue or a hard tumor of bonelike structure developing on a bone (homoplastic osteoma) or on other structures (heteroplastic osteoma). (from dorland, 27th ed)
  • Osteoma, Osteoid

    a benign osteoblastic tumor with central vascularized nidus surrounded by normal reactive bone. it occurs especially in second decade of life most commonly in the femoral neck but can occur in any bone and any site within a bone.
  • Osteomalacia

    disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. it is the adult form of rickets resulting from disruption of vitamin d; phosphorus; or calcium homeostasis.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
alveolar ridge or process upperC41.0C79.51D16.4D48.0D49.2
bone (periosteum) calvariumC41.0C79.51D16.4D48.0D49.2
bone (periosteum) clivusC41.0C79.51D16.4D48.0D49.2
bone (periosteum) cranialC41.0C79.51D16.4D48.0D49.2
bone (periosteum) ethmoid (labyrinth)C41.0C79.51D16.4D48.0D49.2
bone (periosteum) faceC41.0C79.51D16.4D48.0D49.2
bone (periosteum) frontalC41.0C79.51D16.4D48.0D49.2
bone (periosteum) hyoidC41.0C79.51D16.4D48.0D49.2
bone (periosteum) malarC41.0C79.51D16.4D48.0D49.2
bone (periosteum) mastoidC41.0C79.51D16.4D48.0D49.2
bone (periosteum) maxilla, maxillary (superior)C41.0C79.51D16.4D48.0D49.2
bone (periosteum) nose, nasalC41.0C79.51D16.4D48.0D49.2
bone (periosteum) occipitalC41.0C79.51D16.4D48.0D49.2
bone (periosteum) orbitC41.0C79.51D16.4D48.0D49.2
bone (periosteum) parietalC41.0C79.51D16.4D48.0D49.2
bone (periosteum) sella turcicaC41.0C79.51D16.4D48.0D49.2
bone (periosteum) skullC41.0C79.51D16.4D48.0D49.2
bone (periosteum) sphenoidC41.0C79.51D16.4D48.0D49.2
bone (periosteum) temporalC41.0C79.51D16.4D48.0D49.2
bone (periosteum) turbinateC41.0C79.51D16.4D48.0D49.2
bone (periosteum) vomerC41.0C79.51D16.4D48.0D49.2
bone (periosteum) zygomaticC41.0C79.51D16.4D48.0D49.2
calvariumC41.0C79.51D16.4D48.0D49.2
clivusC41.0C79.51D16.4D48.0D49.2
ethmoid (sinus) bone or labyrinthC41.0C79.51D16.4D48.0D49.2
frontalC41.0C79.51D16.4D48.0D49.2
frontal boneC41.0C79.51D16.4D48.0D49.2
jaw bone upperC41.0C79.51D16.4
malarC41.0C79.51D16.4D48.0D49.2
mastoid (air cells) (antrum) (cavity) bone or processC41.0C79.51D16.4D48.0D49.2
maxilla, maxillary (superior)C41.0C79.51D16.4D48.0D49.2
maxilla, maxillary (superior) alveolar ridge or process (carcinoma)C41.0C79.51D16.4D48.0D49.2
nose, nasal boneC41.0C79.51D16.4D48.0D49.2
nose, nasal turbinate (mucosa) boneC41.0C79.51D16.4D48.0D49.2
occipitalC41.0C79.51D16.4D48.0D49.2
occipital boneC41.0C79.51D16.4D48.0D49.2
orbit boneC41.0C79.51D16.4D48.0D49.2
parietalC41.0C79.51D16.4D48.0D49.2
parietal boneC41.0C79.51D16.4D48.0D49.2
sella turcica boneC41.0C79.51D16.4D48.0D49.2
sinus (accessory) bone (any)C41.0C79.51D16.4D48.0D49.2
skullC41.0C79.51D16.4D48.0D49.2
sphenoid boneC41.0C79.51D16.4D48.0D49.2
temporalC41.0C79.51D16.4D48.0D49.2
temporal boneC41.0C79.51D16.4D48.0D49.2
turbinate (bone)C41.0C79.51D16.4D48.0D49.2
vomerC41.0C79.51D16.4D48.0D49.2

Patient EducationClinical

Benign Tumors

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D16.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
213.0 Ben neo skull/face bone
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D16.4Overview

Is D16.4 (Benign neoplasm of bone and articular cartilage) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report benign neoplasm of bones of skull and face on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D16.4 group to?

When benign neoplasm of bones of skull and face is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D16.4?

Under the General Equivalence Mappings, benign neoplasm of bones of skull and face converts to ICD-9-CM 213.0 (ben neo skull/face bone). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.