2025 ICD-10-CM Diagnosis Code Z14.8
Genetic carrier of other disease
- ICD-10-CM Code:
- Z14.8
- ICD-10 Code for:
- Genetic carrier of other disease
- Is Billable?
- Yes - Valid for Submission
- Code Navigator:
Z14.8 is a billable diagnosis code used to specify a medical diagnosis of genetic carrier of other disease. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.
This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.
Approximate Synonyms
The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.
- Asymptomatic carrier of hereditary factor VIII deficiency disease
- Carrier of alpha thalassemia
- Carrier of Becker muscular dystrophy
- Carrier of beta thalassemia
- Carrier of Bloom syndrome
- Carrier of Canavan disease
- Carrier of Charcot-Marie-Tooth disease
- Carrier of chromosome disorder
- Carrier of chromosome translocation
- Carrier of classical phenylketonuria
- Carrier of congenital cystic kidney disease
- Carrier of Cowden syndrome
- Carrier of dihydrolipoamide dehydrogenase deficiency
- Carrier of Duchenne muscular dystrophy
- Carrier of familial adenomatous polyposis
- Carrier of familial combined hyperlipidemia
- Carrier of familial dysautonomia
- Carrier of familial hypercholesterolemia
- Carrier of Fanconi anemia group C
- Carrier of fragile X chromosome
- Carrier of galactosemia
- Carrier of Gaucher disease
- Carrier of glycogen storage disease
- Carrier of hemochromatosis
- Carrier of hemochromatosis HFE gene mutation
- Carrier of hemoglobinopathy C disorder
- Carrier of hemoglobinopathy disorder
- Carrier of hemoglobinopathy E disorder
- Carrier of hereditary factor IX deficiency disease
- Carrier of hereditary factor VIII deficiency disease
- Carrier of hereditary factor VIII deficiency disease
- Carrier of heritable cancer
- Carrier of high risk cancer mutation gene
- Carrier of Joubert syndrome with oculorenal defect
- Carrier of maple syrup urine disease type IB
- Carrier of metabolic disorder
- Carrier of mitochondrial defect
- Carrier of mucolipidosis type IV
- Carrier of muscular dystrophy
- Carrier of myotonic dystrophy
- Carrier of Nebulin-related nemaline myopathy
- Carrier of neurogenetic disorder
- Carrier of Niemann-Pick disease type A
- Carrier of nonsyndromic deafness
- Carrier of sickle cell gene mutation
- Carrier of spinal muscular atrophy
- Carrier of spinocerebellar ataxia
- Carrier of Tay Sachs disease gene mutation
- Carrier of Usher syndrome type 1F
- Carrier of Usher syndrome type 3
- Carrier of Von Hippel-Lindau syndrome
- Carrier of von Willebrand disease
- Familial disease
- Fragile X chromosome
- Fragile X syndrome
- Gastrointestinal hormone level - finding
- Genetic disorder carrier
- Genetic predisposition
- Hemophilia carrier
- Hereditary alpha-tryptasemia trait detected
- Hereditary disease
- Manifesting female carrier of X-linked muscular dystrophy
- Manifesting female carrier of X-linked muscular dystrophy
- Maternally inherited mitochondrial deoxyribonucleic acid disease
- Symptomatic carrier of hereditary factor VIII deficiency disease
- Symptomatic form of fragile X syndrome in female carrier
- Symptomatic form of muscular dystrophy of Duchenne and Becker in female carrier
- X-linked muscular dystrophy with abnormal dystrophin
- X-linked muscular dystrophy with abnormal dystrophin
- X-linked muscular dystrophy with limb girdle distribution
- X-linked muscular dystrophy with limb girdle distribution
Clinical Classification
Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.
They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.
Other specified status
CCSR Code: FAC025
Inpatient Default: X - Not applicable.
Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Clinical Information
Fragile X Syndrome
a condition characterized genotypically by mutation of the distal end of the long arm of the x chromosome (at gene loci fraxa or fraxe) and phenotypically by cognitive impairment, hyperactivity, seizures, language delay, and enlargement of the ears, head, and testes. intellectual disability occurs in nearly all males and roughly 50% of females with the full mutation of fraxa. (from menkes, textbook of child neurology, 5th ed, p226)Fragile X Syndrome
a genetic syndrome caused by mutations in the fmr1 gene which is responsible for the expression of the fragile x mental retardation 1 protein. this protein participates in neural development. this syndrome is manifested with mental, emotional, behavioral, physical, and learning disabilities.
Index to Diseases and Injuries References
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Carrier (suspected) of
- - genetic - Z14.8
- - Genetic
- - carrier (status)
- - specified NEC - Z14.8
- - carrier (status)
Code Edits
The Medicare Code Editor (MCE) detects errors and inconsistencies in ICD-10-CM diagnosis coding that can affect Medicare claim validity. These Medicare code edits help medical coders and billing professionals determine when a diagnosis code is not appropriate as a principal diagnosis, does not meet coverage criteria. Use this list to verify whether a code is valid for Medicare billing and to avoid claim rejections or denials due to diagnosis coding issues.
Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.
Present on Admission (POA)
Z14.8 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.
CMS POA Indicator Options and Definitions
POA Indicator: Y
Reason: Diagnosis was present at time of inpatient admission.
CMS Pays CC/MCC DRG? YES
POA Indicator: N
Reason: Diagnosis was not present at time of inpatient admission.
CMS Pays CC/MCC DRG? NO
POA Indicator: U
Reason: Documentation insufficient to determine if the condition was present at the time of inpatient admission.
CMS Pays CC/MCC DRG? NO
POA Indicator: W
Reason: Clinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.
CMS Pays CC/MCC DRG? YES
POA Indicator: 1
Reason: Unreported/Not used - Exempt from POA reporting.
CMS Pays CC/MCC DRG? NO
Convert Z14.8 to ICD-9-CM
Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.
Genetic carrier stat NEC
ICD-9-CM: V83.89
This is a direct match with no additional mapping qualifiers. The absence of a flag generally means the mapping is considered exact or precise. In other words, the ICD-10 code maps cleanly to the ICD-9 code without qualification, approximation, or needing multiple codes.
Patient Education
Genetic Disorders
Genes are the building blocks of heredity. They are passed from parent to child. They hold DNA, the instructions for making proteins. Proteins do most of the work in cells. They move molecules from one place to another, build structures, break down toxins, and do many other maintenance jobs.
Sometimes there is a mutation, a change in a gene or genes. The mutation changes the gene's instructions for making a protein, so the protein does not work properly or is missing entirely. This can cause a medical condition called a genetic disorder.
You can inherit a gene mutation from one or both parents. A mutation can also happen during your lifetime.
There are three types of genetic disorders:
- Single-gene disorders, where a mutation affects one gene. Sickle cell anemia is an example.
- Chromosomal disorders, where chromosomes (or parts of chromosomes) are missing or changed. Chromosomes are the structures that hold our genes. Down syndrome is a chromosomal disorder.
- Complex disorders, where there are mutations in two or more genes. Often your lifestyle and environment also play a role. Colon cancer is an example.
Genetic tests on blood and other tissue can identify genetic disorders.
NIH: National Library of Medicine
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.
