ICD-10 Code Z15.03

Genetic susceptibility to malignant neoplasm of prostate

Version 2019 Billable Code Diagnoses For Males Only Unacceptable Principal Diagnosis POA Exempt
ICD-10: Z15.03
Short Description:Genetic susceptibility to malignant neoplasm of prostate
Long Description:Genetic susceptibility to malignant neoplasm of prostate

Valid for Submission

ICD-10 Z15.03 is a billable code used to specify a medical diagnosis of genetic susceptibility to malignant neoplasm of prostate. The code is valid for the year 2019 for the submission of HIPAA-covered transactions.

Code Classification

  • Factors influencing health status and contact with health services (Z00–Z99)
    • Genetic carrier and genetic susceptibility to disease (Z14-Z15)
      • Genetic susceptibility to disease (Z15)

Information for Medical Professionals

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10 Code Edits are applicable to this code:

  • Diagnoses for males only - Diagnoses for males only.
  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual’s health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Convert Z15.03 to ICD-9

The following crosswalk between ICD-10 to ICD-9 is based based on the General Equivalence Mappings (GEMS) information:

  • V84.03 - Genetc sus mal neo prost

Present on Admission (POA)

Z15.03 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement.

CMS POA Indicator Options and Definitions
POA Indicator CodePOA Reason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code Z15.03 are found in the index:


Information for Patients


Prostate Cancer

The prostate is the gland below a man's bladder that produces fluid for semen. Prostate cancer is common among older men. It is rare in men younger than 40. Risk factors for developing prostate cancer include being over 65 years of age, family history, and being African-American.

Symptoms of prostate cancer may include

  • Problems passing urine, such as pain, difficulty starting or stopping the stream, or dribbling
  • Low back pain
  • Pain with ejaculation

To diagnose prostate cancer, you doctor may do a digital rectal exam to feel the prostate for lumps or anything unusual. You may also get a blood test for prostate-specific antigen (PSA). These tests are also used in prostate cancer screening, which looks for cancer before you have symptoms. If your results are abnormal, you may need more tests, such as an ultrasound, MRI, or biopsy.

Treatment often depends on the stage of the cancer. How fast the cancer grows and how different it is from surrounding tissue helps determine the stage. Men with prostate cancer have many treatment options. The treatment that's best for one man may not be best for another. The options include watchful waiting, surgery, radiation therapy, hormone therapy, and chemotherapy. You may have a combination of treatments.

NIH: National Cancer Institute

  • Cryotherapy for prostate cancer (Medical Encyclopedia)
  • Digital rectal exam (Medical Encyclopedia)
  • Gleason grading system (Medical Encyclopedia)
  • Hormone therapy for prostate cancer (Medical Encyclopedia)
  • Pelvic (between the hips) radiation - discharge (Medical Encyclopedia)
  • Prostate brachytherapy (Medical Encyclopedia)
  • Prostate cancer (Medical Encyclopedia)
  • Prostate cancer - treatment (Medical Encyclopedia)
  • Prostate cancer staging (Medical Encyclopedia)
  • Understanding Chemotherapy - NIH - Easy-to-Read (National Cancer Institute)
  • Understanding your prostate cancer risk (Medical Encyclopedia)
  • What to Know about Brachytherapy (A Type of Internal Radiation Therapy) - NIH - Easy-to-Read (National Cancer Institute)
  • What to Know about External Beam Radiation Therapy - NIH - Easy-to-Read (National Cancer Institute)

[Learn More]

ICD-10 Footnotes

General Equivalence Map Definitions
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.