ICD-10 Code T50.4X5

Adverse effect of drugs affecting uric acid metabolism

Version 2019 Replaced Code Non-Billable Code Adverse Effect

Not Valid for Submission

T50.4X5 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of drugs affecting uric acid metabolism. The code is NOT valid for the year 2020 for the submission of HIPAA-covered transactions.

ICD-10: T50.4X5
Short Description:Adverse effect of drugs affecting uric acid metabolism
Long Description:Adverse effect of drugs affecting uric acid metabolism

Consider the following ICD-10 codes with a higher level of specificity:

  • T50.4X5A - Adverse effect of drugs affecting uric acid metabolism, initial encounter
  • T50.4X5D - Adverse effect of drugs affecting uric acid metabolism, subsequent encounter
  • T50.4X5S - Adverse effect of drugs affecting uric acid metabolism, sequela

Replaced Code

This code was replaced in the 2020 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2019. This code was replaced for the FY 2020 (October 1, 2019 - September 30, 2020).

  • K59.03 - Drug induced constipation

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Diuretics and oth and unsp drug/meds/biol subst (T50)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (first year ICD-10-CM implemented into the HIPAA mandated code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Medical Professionals

Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Allopurinol adverse reaction
  • Allopurinol hypersensitivity syndrome
  • Colchicine adverse reaction
  • Colchicum alkaloid adverse reaction
  • Drug for the treatment of gout adverse reaction
  • Drug for the treatment of gout adverse reaction
  • Drug for the treatment of gout adverse reaction
  • Drug reaction with eosinophilia and systemic symptoms
  • Gout drug side effect
  • Gout monitoring status
  • Probenecid adverse reaction
  • Repeat prescription drug side effect
  • Repeat prescription monitoring status
  • Sulfinpyrazone adverse reaction
  • Uricosuric agent adverse reaction
  • Xanthine oxidase inhibitor adverse reaction

Table of Drugs and Chemicals

The code T50.4X5 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. Use as many codes as necessary to describe all reported drugs, medicinal or chemical substances.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
self-harm
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AllopurinolT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
AtophanT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
BenemidT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
BenzbromaroneT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
CinchophenT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
ColchicineT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
EtebenecidT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
EthebenecidT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
NeocinchophenT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
OxipurinolT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
PhenoquinT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
ProbenecidT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
Spindle inactivatorT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
SulfinpyrazoneT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
SulphinpyrazoneT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
TisopurineT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
Urate oxidaseT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
Uric acid metabolism drug NECT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
Uricosuric agentT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6

Information for Patients


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as ginkgo and blood thinners
  • Drugs and diseases, such as aspirin and peptic ulcers

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.


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ICD-10 Footnotes

General Equivalence Map Definitions
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.