2021 ICD-10-CM Code T38.3X

Poisoning by, adverse effect of and underdosing of insulin and oral hypoglycemic [antidiabetic] drugs

Version 2021
Replaced Code
Non-Billable Code

Not Valid for Submission

T38.3X is a "header" nonspecific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of poisoning by, adverse effect of and underdosing of insulin and oral hypoglycemic [antidiabetic] drugs. The code is NOT valid for the year 2021 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

ICD-10:T38.3X
Short Description:Insulin and oral hypoglycemic drugs
Long Description:Poisoning by, adverse effect of and underdosing of insulin and oral hypoglycemic [antidiabetic] drugs

Code Classification

Specific Coding for Insulin and oral hypoglycemic drugs

Header codes like T38.3X require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for insulin and oral hypoglycemic drugs:

  • T38.3X1 - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, accidental (unintentional)
  • T38.3X1A - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, accidental (unintentional), initial encounter
  • T38.3X1D - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, accidental (unintentional), subsequent encounter
  • T38.3X1S - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, accidental (unintentional), sequela
  • T38.3X2 - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, intentional self-harm
  • T38.3X2A - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, intentional self-harm, initial encounter
  • T38.3X2D - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, intentional self-harm, subsequent encounter
  • T38.3X2S - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, intentional self-harm, sequela
  • T38.3X3 - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, assault
  • T38.3X3A - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, assault, initial encounter
  • T38.3X3D - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, assault, subsequent encounter
  • T38.3X3S - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, assault, sequela
  • T38.3X4 - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, undetermined
  • T38.3X4A - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, undetermined, initial encounter
  • T38.3X4D - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, undetermined, subsequent encounter
  • T38.3X4S - Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, undetermined, sequela
  • T38.3X5 - Adverse effect of insulin and oral hypoglycemic [antidiabetic] drugs
  • T38.3X5A - Adverse effect of insulin and oral hypoglycemic [antidiabetic] drugs, initial encounter
  • T38.3X5D - Adverse effect of insulin and oral hypoglycemic [antidiabetic] drugs, subsequent encounter
  • T38.3X5S - Adverse effect of insulin and oral hypoglycemic [antidiabetic] drugs, sequela
  • T38.3X6 - Underdosing of insulin and oral hypoglycemic [antidiabetic] drugs
  • T38.3X6A - Underdosing of insulin and oral hypoglycemic [antidiabetic] drugs, initial encounter
  • T38.3X6D - Underdosing of insulin and oral hypoglycemic [antidiabetic] drugs, subsequent encounter
  • T38.3X6S - Underdosing of insulin and oral hypoglycemic [antidiabetic] drugs, sequela

Replaced Code

This code was replaced in the 2021 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2020. This code was replaced for the FY 2021 (October 1, 2020 - September 30, 2021).


  • K59.03 - Drug induced constipation

Information for Patients


Diabetes Medicines

Diabetes means your blood glucose, or blood sugar, levels are too high. If you can't control your diabetes with wise food choices and physical activity, you may need diabetes medicines. The kind of medicine you take depends on your type of diabetes, your schedule, and your other health conditions.

With type 1 diabetes, your pancreas does not make insulin. Insulin is a hormone that helps glucose get into your cells to give them energy. Without insulin, too much glucose stays in your blood. If you have type 1 diabetes, you will need to take insulin.

Type 2 diabetes, the most common type, can start when the body doesn't use insulin as it should. If your body can't keep up with the need for insulin, you may need to take pills. Along with meal planning and physical activity, diabetes pills help people with type 2 diabetes or gestational diabetes keep their blood glucose levels on target. Several kinds of pills are available. Each works in a different way. Many people take two or three kinds of pills. Some people take combination pills. Combination pills contain two kinds of diabetes medicine in one tablet. Some people take pills and insulin.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


[Learn More in MedlinePlus]

Drug Reactions

Also called: Side effects

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.


[Learn More in MedlinePlus]

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)