2024 ICD-10-CM Diagnosis Code T36.2X5

Adverse effect of chloramphenicol group

ICD-10-CM Code:
T36.2X5
ICD-10 Code for:
Adverse effect of chloramphenicol group
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of systemic antibiotics
        (T36)

T36.2X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of chloramphenicol group. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of chloramphenicol group

Non-specific codes like T36.2X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of chloramphenicol group:

  • Use T36.2X5A for initial encounter - BILLABLE CODE

  • Use T36.2X5D for subsequent encounter - BILLABLE CODE

  • Use T36.2X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Chloramphenicol adverse reaction
  • Chloramphenicol-induced neutropenia
  • Drug-induced neutropenia
  • Thiamphenicol adverse reaction

Clinical Information

  • Chloramphenicol

    an antibiotic first isolated from cultures of streptomyces venequelae in 1947 but now produced synthetically. it has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. it acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (from martindale, the extra pharmacopoeia, 29th ed, p106)
  • Chloramphenicol O-Acetyltransferase

    an enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. the enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. ec 2.3.1.28.
  • Chloramphenicol Resistance

    nonsusceptibility of bacteria to the action of chloramphenicol, a potent inhibitor of protein synthesis in the 50s ribosomal subunit where amino acids are added to nascent bacterial polypeptides.
  • Thiamphenicol

    a methylsulfonyl analog of chloramphenicol. it is an antibiotic and immunosuppressive agent.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of systemic antibiotics (T36). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
ChloramphenicolT36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
Chloramphenicol
  »ENT agent
T36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
Chloramphenicol
  »ophthalmic preparation
T36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
Chloramphenicol
  »topical NEC
T36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
ChloromycetinT36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
Chloromycetin
  »ENT agent
T36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
Chloromycetin
  »ophthalmic preparation
T36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
Chloromycetin
  »otic solution
T36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
Chloromycetin
  »topical NEC
T36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
ClopononeT36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
CloramfenicolT36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6
ThiamphenicolT36.2X1T36.2X2T36.2X3T36.2X4T36.2X5T36.2X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.