2026 ICD-10-CM Diagnosis Code N04Nephrotic syndrome

ICD-10-CM Codes›N00–N99›N00-N08›N04

ICD-10-CM N04
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

N04 is a non-billable ICD-10-CM category code for nephrotic syndrome, so it cannot be submitted on claims. Use a more specific code from this category instead, such as N04.0, N04.1, N04.20, and N04.21.

Code Identity

ICD-10-CM Code
N04
Billable Status
No — Non-Billable Category
Code Describes
Nephrotic syndrome
Short Description
Nephrotic syndrome
Same as the full description in the CMS dataset.
Chapter
N00-N08
Glomerular diseases

Code Classification

ChapterN00–N99Diseases of the genitourinary system
SectionN00-N08Glomerular diseases
CategoryN04Nephrotic syndrome
This CodeN04Nephrotic syndrome

Specific Coding for Nephrotic syndromeOverview

Non-specific codes like N04 require more characters. Use one of these billable codes instead:

  • Use N04.0 for Nephrotic syndrome with minor glomerular abnormality

  • Use N04.1 for Nephrotic syndrome with focal and segmental glomerular lesions

  • N04.2 for Nephrotic syndrome with diffuse membranous glomerulonephritis

  • Use N04.20 for Nephrotic syndrome with diffuse membranous glomerulonephritis, unspecified

  • Use N04.21 for Primary membranous nephropathy with nephrotic syndrome

  • Use N04.22 for Secondary membranous nephropathy with nephrotic syndrome

  • Use N04.29 for Other nephrotic syndrome with diffuse membranous glomerulonephritis

  • Use N04.3 for Nephrotic syndrome with diffuse mesangial proliferative glomerulonephritis

  • Use N04.4 for Nephrotic syndrome with diffuse endocapillary proliferative glomerulonephritis

  • Use N04.5 for Nephrotic syndrome with diffuse mesangiocapillary glomerulonephritis

  • Use N04.6 for Nephrotic syndrome with dense deposit disease

  • Use N04.7 for Nephrotic syndrome with diffuse crescentic glomerulonephritis

  • Use N04.8 for Nephrotic syndrome with other morphologic changes

  • Use N04.9 for Nephrotic syndrome with unspecified morphologic changes

  • Use N04.A for Nephrotic syndrome with C3 glomerulonephritis

  • N04.B for Nephrotic syndrome with immune complex membranoproliferative glomerulonephritis (IC-MPGN)

  • Use N04.B1 for Nephrotic syndrome with idiopathic immune complex membranoproliferative glomerulonephritis (IC-MPGN)

  • Use N04.B2 for Nephrotic syndrome with secondary immune complex membranoproliferative glomerulonephritis (IC-MPGN)

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Includes

  • congenital nephrotic syndrome
  • lipoid nephrosis

Clinical InformationClinical

  • Nephrosis, Lipoid

    a kidney disease with no or minimal histological glomerular changes on light microscopy and with no immune deposits. it is characterized by lipid accumulation in the epithelial cells of kidney tubules and in the urine. patients usually show nephrotic syndrome indicating the presence of proteinuria with accompanying edema.

  • Nephrotic Syndrome

    a condition characterized by severe proteinuria, greater than 3.5 g/day in an average adult. the substantial loss of protein in the urine results in complications such as hypoproteinemia; generalized edema; hypertension; and hyperlipidemias. diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Patient EducationClinical

Kidney Diseases

You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About N04Overview

Is N04 (Nephrotic syndrome) a billable code?

No. This is a category header that groups the codes for nephrotic syndrome, and headers cannot be submitted on claims. Claims for nephrotic syndrome need a more specific code from this category, such as N04.0, N04.1, and N04.20.