2024 ICD-10-CM Diagnosis Code G90.3

Multi-system degeneration of the autonomic nervous system

ICD-10-CM Code:
ICD-10 Code for:
Multi-system degeneration of the autonomic nervous system
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Code Navigator:

Code Classification

  • Diseases of the nervous system
    • Other disorders of the nervous system
      • Disorders of autonomic nervous system

G90.3 is a billable diagnosis code used to specify a medical diagnosis of multi-system degeneration of the autonomic nervous system. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Amyotrophic lateral sclerosis plus syndrome
  • Amyotrophic lateral sclerosis with multiple system atrophy
  • Ataxia due to multiple system atrophy, cerebellar variant
  • Chronic hypotension
  • Chronic orthostatic hypotension
  • Dementia due to multiple system atrophy
  • Multiple system atrophy
  • Multiple system atrophy
  • Multiple system atrophy, cerebellar variant
  • Multiple system atrophy, Parkinson's variant
  • Multisystem degeneration of autonomic nervous system
  • Orthostatic hypotension co-occurrent and due to Parkinson's disease
  • Parkinsonian syndrome with idiopathic orthostatic hypotension
  • Parkinson's disease
  • Pure autonomic failure
  • Sympathotonic orthostatic hypotension
  • Synucleinopathy
  • Synucleinopathy
  • Synucleinopathy
  • Synucleinopathy
  • Synucleinopathy

Clinical Classification

Clinical Information

  • Multiple System Atrophy

    a syndrome complex composed of three conditions which represent clinical variants of the same disease process: striatonigral degeneration; shy-drager syndrome; and the sporadic form of olivopontocerebellar atrophies. clinical features include autonomic, cerebellar, and basal ganglia dysfunction. pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (from adams et al., principles of neurology, 6th ed, p1076; baillieres clin neurol 1997 apr;6(1):187-204; med clin north am 1999 mar;83(2):381-92)
  • Pure Autonomic Failure

    a degenerative disease of the autonomic nervous system that is characterized by idiopathic orthostatic hypotension and a greatly reduced level of catecholamines. no other neurological deficits are present.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert G90.3 to ICD-9-CM

  • ICD-9-CM Code: 333.0 - Degen basal ganglia NEC
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education

Autonomic Nervous System Disorders

Your autonomic nervous system is the part of your nervous system that controls involuntary actions, such as the beating of your heart and the widening or narrowing of your blood vessels. When something goes wrong in this system, it can cause serious problems, including:

  • Blood pressure problems
  • Heart problems
  • Trouble with breathing and swallowing
  • Erectile dysfunction in men

Autonomic nervous system disorders can occur alone or as the result of another disease, such as Parkinson's disease, alcoholism and diabetes. Problems can affect either part of the system, as in complex regional pain syndromes, or all of the system. Some types are temporary, but many worsen over time. When they affect your breathing or heart function, these disorders can be life-threatening.

Some autonomic nervous system disorders get better when an underlying disease is treated. Often, however, there is no cure. In that case, the goal of treatment is to improve symptoms.

NIH: National Institute of Neurological Disorders and Stroke

[Learn More in MedlinePlus]

Multiple system atrophy

Multiple system atrophy is a progressive brain disorder that affects movement and balance and disrupts the function of the autonomic nervous system. The autonomic nervous system controls body functions that are mostly involuntary, such as regulation of blood pressure. The most frequent autonomic symptoms associated with multiple system atrophy are a sudden drop in blood pressure upon standing (orthostatic hypotension), urinary difficulties, and erectile dysfunction in men.

Researchers have described two major types of multiple system atrophy, which are distinguished by their major signs and symptoms at the time of diagnosis. In one type, known as MSA-P, a group of movement abnormalities called parkinsonism are predominant. These abnormalities include unusually slow movement (bradykinesia), muscle rigidity, tremors, and an inability to hold the body upright and balanced (postural instability). The other type of multiple system atrophy, known as MSA-C, is characterized by cerebellar ataxia, which causes problems with coordination and balance. This form of the condition can also include speech difficulties (dysarthria) and problems controlling eye movement.

Multiple system atrophy usually occurs in older adults; on average, signs and symptoms appear around age 55. The condition worsens with time, and affected individuals survive an average of 10 years after the signs and symptoms first appear.

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.