ICD-10-CM Code G12.23

Primary lateral sclerosis

Version 2021 Billable Code

Valid for Submission

G12.23 is a billable code used to specify a medical diagnosis of primary lateral sclerosis. The code is valid for the fiscal year 2021 for the submission of HIPAA-covered transactions. The ICD-10-CM code G12.23 might also be used to specify conditions or terms like juvenile primary lateral sclerosis or primary lateral sclerosis.

Short Description:Primary lateral sclerosis
Long Description:Primary lateral sclerosis

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code G12.23 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Juvenile primary lateral sclerosis
  • Primary lateral sclerosis

Clinical Information

  • MOTOR NEURON DISEASE-. diseases characterized by a selective degeneration of the motor neurons of the spinal cord brainstem or motor cortex. clinical subtypes are distinguished by the major site of degeneration. in amyotrophic lateral sclerosis there is involvement of upper lower and brainstem motor neurons. in progressive muscular atrophy and related syndromes see muscular atrophy spinal the motor neurons in the spinal cord are primarily affected. with progressive bulbar palsy bulbar palsy progressive the initial degeneration occurs in the brainstem. in primary lateral sclerosis the cortical neurons are affected in isolation. adams et al. principles of neurology 6th ed p1089

Replacement Code

G1223 replaces the following previously assigned ICD-10 code(s):

  • G12.29 - Other motor neuron disease

Convert G12.23 to ICD-9

  • 335.24 - Prim lateral sclerosis

Code Classification

  • Diseases of the nervous system (G00–G99)
    • Systemic atrophies primarily affecting the central nervous system (G10-G14)
      • Spinal muscular atrophy and related syndromes (G12)

Code History

  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021