2022 ICD-10-CM Code G12.2

Motor neuron disease

Version 2021

Not Valid for Submission

ICD-10:G12.2
Short Description:Motor neuron disease
Long Description:Motor neuron disease

Code Classification

  • Diseases of the nervous system (G00–G99)
    • Systemic atrophies primarily affecting the central nervous system (G10-G14)
      • Spinal muscular atrophy and related syndromes (G12)

G12.2 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of motor neuron disease. The code is not specific and is NOT valid for the year 2022 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding for Motor neuron disease

Non-specific codes like G12.2 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for motor neuron disease:

  • BILLABLE CODE - Use G12.20 for Motor neuron disease, unspecified
  • BILLABLE CODE - Use G12.21 for Amyotrophic lateral sclerosis
  • BILLABLE CODE - Use G12.22 for Progressive bulbar palsy
  • BILLABLE CODE - Use G12.23 for Primary lateral sclerosis
  • BILLABLE CODE - Use G12.24 for Familial motor neuron disease
  • BILLABLE CODE - Use G12.25 for Progressive spinal muscle atrophy
  • BILLABLE CODE - Use G12.29 for Other motor neuron disease

Clinical Information

Information for Patients


Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons transmit messages from your brain and spinal cord to your voluntary muscles - the ones you can control, like in your arms and legs. At first, this causes mild muscle problems. Some people notice

Eventually, you lose your strength and cannot move. When muscles in your chest fail, you cannot breathe. A breathing machine can help, but most people with ALS die from respiratory failure.

The disease usually strikes between age 40 and 60. More men than women get it. No one knows what causes ALS. It can run in families, but usually it strikes at random. There is no cure. Medicines can relieve symptoms and, sometimes, prolong survival.

NIH: National Institute of Neurological Disorders and Stroke


[Learn More in MedlinePlus]

Neuromuscular Disorders

Neuromuscular disorders affect your neuromuscular system. They can cause problems with

These disorders can cause your muscles to become weak and waste away. You may also have symptoms such as spasms, twitching, and pain.

Examples of neuromuscular disorders include

There can be different causes for these diseases. Many of them are genetic.This means they are inherited (run in families) or are caused by a new mutation in your genes. Some neuromuscular disorders are autoimmune diseases. Sometimes the cause is unknown.

Many neuromuscular diseases have no cure. But treatments may improve symptoms, increase mobility, and lengthen life.


[Learn More in MedlinePlus]

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)