Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere (G13)
ICD-10 code section G13 covers systemic atrophies that primarily affect the central nervous system but occur as part of other diseases classified elsewhere. These codes are used to document neurological degeneration linked to various underlying medical conditions, including cancers and endocrine disorders.
This group includes specific codes like G13.0 for paraneoplastic neuromyopathy and neuropathy, which involves nerve damage related to cancers such as multiple myeloma or plasma cell dyscrasias; often described using terms like paraneoplastic peripheral neuropathy or neuropathy associated with dysproteinemias. Code G13.1 refers to other systemic atrophies affecting the CNS tied to neoplastic diseases, including paraneoplastic cerebellar degeneration, sometimes called secondary cerebellar degeneration. G13.2 applies to systemic atrophy from myxedema, a severe form of hypothyroidism, with no listed synonyms. Finally, G13.8 captures other systemic CNS atrophies due to various diseases elsewhere, also linked with terms like myxedema cerebellar degeneration. These ICD-10 codes enable precise classification of neurological decline when it arises secondary to systemic or neoplastic disorders.
Diseases of the nervous system (G00–G99)
Systemic atrophies primarily affecting the central nervous system (G10-G14)
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
- G13.0 Paraneoplastic neuromyopathy and neuropathy
- G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
- G13.2 Systemic atrophy primarily affecting the central nervous system in myxedema
- G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere (G13)
Clinical Terms
The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.
Paraneoplastic Cerebellar Degeneration
Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
