2027 ICD-10-CM Diagnosis Code F53.0Postpartum depression

ICD-10-CM Codes›F01–F99›F50-F59›F53

ICD-10-CM F53.0
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

F53.0 is a billable ICD-10-CM diagnosis code for postpartum depression. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 881. The code is restricted by the Medicare Code Editor to maternity cases (age 9 through 64). Coders also document this condition as decline in Edinburgh postnatal depression scale score. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Complications specified during the puerperium and Depressive disorders.

F53.0 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 132 for payment year 2027.

Code Identity

ICD-10-CM Code
F53.0
Billable Status
Yes — Valid for Submission
Code Describes
Postpartum depression
Short Description
Postpartum depression
Same as the full description in the CMS dataset.
Parent Code
F53
Mental and behavioral disorders associated with the puerperium, not elsewhere classified

Code Classification

ChapterF01–F99Mental and behavioural disorders
SectionF50-F59Behavioral syndromes associated with physiological disturbances and physical factors
CategoryF53Mental and behavioral disorders associated with the puerperium, not elsewhere classified
This CodeF53.0Postpartum depression

Code EditsBilling

Medicare Code Editor checks that affect claim validity for F53.0.

Maternity diagnoses
The Medicare Code Editor detects inconsistencies in maternity cases by checking a patient's age and any diagnosis on the patient's record. The maternity code edits apply to patients age ange is 9–64 years inclusive (e.g., diabetes in pregnancy, antepartum pulmonary complication).

Medicare Risk Adjustment (HCC)Billing

F53.0 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model, but it maps to payment categories in the other CMS models shown below.

CMS-HCC V28 (Medicare Advantage Payment Model)
Not mapped
no payment category in the model that pays 100% of MA risk scores
Prior Model (CMS-HCC V24)
Not mapped under V24
this diagnosis newly risk-adjusts under the V28 model
Part D (RxHCC)
RxHCC 132 — Depression
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Decline in Edinburgh postnatal depression scale score
  • Decline in Edinburgh postnatal depression scale score at 8 months
  • Depressed mood with postpartum onset
  • Major depression in remission
  • Major depressive disorder, single episode with postpartum onset
  • Mild depression
  • Mild postnatal depression
  • Postpartum depression
  • Postpartum major depression in remission
  • Severe postnatal depression

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to F53.0: its own notes plus those printed at F53 and Chapter 5. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 5 (F01-F99) Mental and behavioural disorders applies to 872 codes
  • disorders of psychological development

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Postnatal depression, NOS
  • Postpartum depression, NOS

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From F53 Mental and behavioral disorders associated with the puerperium, not elsewhere classified applies to 2 codes

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 5 (F01-F99) Mental and behavioural disorders applies to 872 codes
  • symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name F53.0, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming F53.0: they are not reported together with it, unless the two conditions are unrelated.

  • O90.6 Postpartum mood disturbance
    postpartum depression (F53.0)

Excludes2 2

These codes carry an Excludes2 note naming F53.0: its condition is not part of those codes, and both may be reported when the patient has both.

  • Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium
    mental and behavioral disorders associated with the puerperium (F53.-) names F53.-, which includes this code
  • Block O85-O92 Complications predominantly related to the puerperium
    mental and behavioral disorders associated with the puerperium (F53.-) names F53.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PRG027
Complications specified during the puerperium
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR MBD002
Depressive disorders
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Depression, Postpartum

    depression in postpartum women, usually within four weeks after giving birth (parturition). the degree of depression ranges from mild transient depression to neurotic or psychotic depressive disorders. (from dsm-iv, p386)

Patient EducationClinical

Postpartum Depression

Having a baby can be exciting, but it can also be stressful and bring many strong emotions. During the postpartum period, which is the time after you give birth, you may have mood swings, crying spells, or feel anxious. These feelings are common and are often called the postpartum "baby blues".

The full article covers:

  • What is postpartum depression?
  • What causes postpartum depression?
  • Who is at risk for postpartum depression?
  • What are the symptoms of postpartum depression?
  • How is postpartum depression diagnosed?
  • What is the treatment for postpartum depression?
  • Can postpartum depression be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement F53.0 replaces the following previously assigned code(s):

  • F53 - Mental and behavrl disorders assoc with the puerperium, NEC
  • F53 - Puerperal psychosis
FY 2019AddedAdded to the ICD-10-CM code setEffective October 1, 2018.
FY 2020–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About F53.0Overview

What is the ICD-10 code for postpartum depression?

The ICD-10-CM code for postpartum depression is F53.0 (sometimes written as F530). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is F53.0 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report postpartum depression on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does F53.0 group to?

When postpartum depression is the principal diagnosis on an inpatient stay, it groups to MS-DRG 881 (depressive Neuroses), which carries a relative weight of 0.8963. Higher weights mean higher Medicare reimbursement.

Who can F53.0 be reported for?

The Medicare Code Editor checks postpartum depression against patient demographics: this code is intended for maternity cases (age 9 through 64). Claims outside these limits are flagged as inconsistent.

Can F53.0 be reported with F30.2?

Not as a rule. The Excludes1 note at F53, which applies to F53.0, lists "mood disorders with psychotic features (F30.2, F31.2, F31.5, F31.64, F32.3, F33.3)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does F53.0 risk-adjust for Medicare Advantage payment?

Not for Medicare Advantage: F53.0 maps to no category in the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 132 (Depression).