MS-DRG · FY 2026 v43.0

MS-DRG 881 – Depressive Neuroses

A Medical DRG in MDC 19 (Mental Diseases & Disorders). Inpatient cases group to DRG 881 when the ICD-10-CM principal diagnosis is one of the 5 codes listed below. Its FY 2026 relative weight is 0.9409 with a geometric mean length of stay of 4.1 days.

Medical DRG – assigned by principal diagnosis✓ Official CMS v43.0 dataset
0.9409
Relative Weight
4.1
Geometric Mean LOS (days)
6.2
Arithmetic Mean LOS (days)
5
Principal Diagnosis Codes
How a case is assigned to DRG 881

The grouper first assigns the case to MDC 19 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here).

ICD-10-CM

Principal Diagnosis Codes 5 codes · 4 categories

F32 Depressive episode2 codes
  • F32.9 Major depressive disorder, single episode, unspecified
  • F32.A Depression, unspecified
F34 Persistent mood [affective] disorders1 code
F43 Reaction to severe stress, and adjustment disorders1 code
  • F43.21 Adjustment disorder with depressed mood
F53 Mental and behavioral disorders associated with the puerperium, not elsewhere classified1 code
  • F53.0 Postpartum depression
ICD-10-PCS

Procedure Codes

Procedure codes do not drive assignment for this DRG. DRG 881 is a Medical DRG, assigned from the principal diagnosis above.

Frequently Asked Questions

What is MS-DRG 881?

MS-DRG 881 (Depressive Neuroses) is a medical DRG in MDC 19 (Mental Diseases & Disorders). Its FY 2026 relative weight is 0.9409 with a geometric mean length of stay of 4.1 days.

How many diagnosis codes group to DRG 881?

5 ICD-10-CM principal diagnosis codes group to this DRG, spanning 4 three-character categories.

What is the relative weight of DRG 881?

The FY 2026 relative weight of this DRG is 0.9409, meaning reimbursement of roughly 0.94 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.

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Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.