2026 ICD-10-CM Diagnosis Code F48.1Depersonalization-derealization syndrome

ICD-10-CM Codes›F01–F99›F40-F48›F48

ICD-10-CM F48.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

F48.1 is a billable ICD-10-CM diagnosis code for depersonalization-derealization syndrome. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Trauma- and stressor-related disorders.

Code Identity

ICD-10-CM Code
F48.1
Billable Status
Yes — Valid for Submission
Code Describes
Depersonalization-derealization syndrome
Short Description
Depersonalization-derealization syndrome
Same as the full description in the CMS dataset.
Parent Code
F48
Other nonpsychotic mental disorders

Code Classification

ChapterF01–F99Mental and behavioural disorders
SectionF40-F48Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders
CategoryF48Other nonpsychotic mental disorders
This CodeF48.1Depersonalization-derealization syndrome

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Depersonalization
  • Depersonalization disorder
  • Depersonalization-derealization syndrome
  • Derealization
  • Derealization syndrome
  • Disturbance of perception associated with conversion and dissociative phenomenon
  • Feels own body is unreal
  • Neurosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Depersonalization(in neurotic state) (neurotic) (syndrome)
    • Derealization(neurotic)
    • Disorder(of)
      • depersonalization
    • Episode
      • depersonalization (in neurotic state)
    • Neurosis, neurotic
      • depersonalization
    • Neurosis, neurotic
      • state
        • with depersonalization episode
    • Psychoneurosis, psychoneurotic
      • depersonalization
    • Reaction
      • psychoneurotic
        • depersonalization
    • State(of)
      • neurotic
        • with depersonalization
    • Syndrome
      • depersonalization (-derealization)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MBD007
Trauma- and stressor-related disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Depersonalization

    state in which an individual perceives or experiences a sensation of unreality concerning the self or the environment; it is seen in disorders such as schizophrenia, affection disorders, organic mental disorders, and personality disorders. (apa, thesaurus of psychological index terms, 8th ed.)

  • CAPS DSM-5 With DSM IV Scoring 2016 Version - Derealization|CAP01-Derealization|CAP01-Derealization|CAP0130

    clinician-administered ptsd scale (current) dsm-5 with dsm iv scoring 2016 version (caps dsm-5 with dsm iv scoring 2016 version) dsm-5 scoring: derealization: persistent or recurrent experiences of unreality of surroundings (e.g., the world around the individual is experienced as unreal, dreamlike, distant, or distorted).

  • Derealization

    a feeling of altered reality characterized by a feeling of unreality, or being unreal.

  • HAMD 24 - Depersonalization and Derealisation|HAMD3-Depersonalization/Derealization|HAMD3-Depersonalization/Derealization|HAMD319

    hamilton depression rating scale-24 item (hamd 24) depersonalization and derealisation.

  • HAMD-21 - Depersonalization and Derealization|HAMD2-Depersonalization/Derealization|HAMD2-Depersonalization/Derealization|HAMD219

    hamilton depression rating scale 21 item (hamd-21) depersonalization and derealization; such as feelings of unreality, nihilistic ideas.

  • Depersonalization Disorder

    a disorder characterized by persistent or recurrent episodes of feeling detached from one's self (either one's body or one's mental processes), although the sufferer remains aware that this is only a feeling and does not represent reality.

  • Aponeurosis

    a flat, tendon-like membrane that serves to bind muscles or to attach muscles to bones.

  • Neurosis

    a form of functional mental illness that manifests in distressed emotional reactions such as anxiety, obsessive thoughts, compulsive behaviors, or irrational fears.

  • Post-Traumatic Stress Disorder|Combat Neurosis|PTSD|PTSD|post-traumatic stress disorder

    an anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. the disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. these symptoms are present for at least one month and the disorder is usually long-term.

Patient EducationClinical

Mental Disorders

Mental disorders (or mental illnesses) are conditions that affect your thinking, feeling, mood, and behavior. They may happen over a short period of time or come and go. Some can be chronic (long-lasting). They can affect your ability to relate to others and function each day..

The full article covers:

  • What are mental disorders?
  • What are some types of mental disorders?
  • What causes mental disorders?
  • Who is at risk for mental disorders?
  • How are mental disorders diagnosed?
  • What are the treatments for mental disorders?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert F48.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
300.6 Depersonalization disord
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About F48.1Overview

Is F48.1 (Other nonpsychotic mental disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report depersonalization-derealization syndrome on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of F48.1?

Under the General Equivalence Mappings, depersonalization-derealization syndrome converts to ICD-9-CM 300.6 (depersonalization disord). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.