2027 ICD-10-CM Diagnosis Code F16.159Hallucinogen abuse with hallucinogen-induced psychotic disorder, unspecified

ICD-10-CM Codes›F01–F99›F10-F19›F16

ICD-10-CM F16.159
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

F16.159 is a billable ICD-10-CM diagnosis code for hallucinogen abuse with hallucinogen-induced psychotic disorder, unspecified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 894 through 897. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hallucinogen-related disorders and Schizophrenia spectrum and other psychotic disorders.

For Medicare Advantage risk adjustment, F16.159 maps to CMS-HCC Category 135 (Drug Use with Psychotic Complications) under the V28 model, adding a risk factor of about 0.424 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
F16.159
Billable Status
Yes — Valid for Submission
Code Describes
Hallucinogen abuse with hallucinogen-induced psychotic disorder, unspecified
Short Description
Hallucinogen abuse w psychotic disorder, unsp
Parent Code
Hallucinogen abuse with hallucinogen-induced psychotic disorder

Code Classification

ChapterF01–F99Mental and behavioural disorders
SectionF10-F19Mental and behavioral disorders due to psychoactive substance use
CategoryF16Hallucinogen related disorders
This CodeF16.159Hallucinogen abuse with hallucinogen-induced psychotic disorder, unspecified

Medicare Risk Adjustment (HCC)Billing

F16.159 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 135— Drug Use with Psychotic Complications
Payment HCC · PY 2027 one of 97 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.424
community, non-dual, aged · ranges 0.297–1.181 across segments
Hierarchy
Supersedes HCC 136, HCC 137, HCC 138, and HCC 139
less severe related categories are not paid alongside HCC 135
Prior Model (CMS-HCC V24)
HCC 54
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 54 · ESRD (V21): HCC 54 · ESRD (V24): HCC 54
ESRD V21 weights: 0.048 dialysis, 0.112–0.352 functioning graft · ESRD V24 weights: 0.111 dialysis, 0.172–1.071 functioning graft
Part D (RxHCC)
Not mapped
F16.159 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to F16.159: its own notes plus those printed at F16.1, F16, and Chapter 5. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From F16 Hallucinogen related disorders applies to 40 codes
  • ecstasy
  • PCP
  • phencyclidine
From Chapter 5 (F01-F99) Mental and behavioural disorders applies to 872 codes
  • disorders of psychological development

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From F16.1 Hallucinogen abuse applies to 14 codes
  • hallucinogen dependence (F16.2-)
  • hallucinogen use, unspecified (F16.9-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 5 (F01-F99) Mental and behavioural disorders applies to 872 codes
  • symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name F16.159, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming F16.159: they are not reported together with it, unless the two conditions are unrelated.

  • F16.2 Hallucinogen dependence
    hallucinogen abuse (F16.1-) names F16.1-, which includes this code
  • F16.9 Hallucinogen use, unspecified
    hallucinogen abuse (F16.1-) names F16.1-, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MBD022
Hallucinogen-related disorders
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR MBD001
Schizophrenia spectrum and other psychotic disorders
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Drug Use and Addiction

Drugs are chemical substances that can change how your body and mind work. They include prescription medicines, over-the-counter medicines, alcohol, tobacco, and illegal drugs.

The full article covers:

  • What are drugs?
  • What is drug use?
  • What is drug addiction?
  • Does everyone who takes drugs become addicted?
  • Who is at risk for drug addiction?
  • What are the signs that someone has a drug problem?
  • What are the treatments for drug addiction?
  • Can drug use and addiction be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert F16.159 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
292.89 Drug mental disorder NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About F16.159Overview

Is F16.159 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hallucinogen abuse with hallucinogen-induced psychotic disorder, unspecified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does F16.159 group to?

When hallucinogen abuse with hallucinogen-induced psychotic disorder, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 894, 897, 895, 896, with relative weights from 0.6272 to 1.6610 depending on complications. Higher weights mean higher Medicare reimbursement.

Can F16.159 be reported with a code from F16.2?

Not as a rule. The Excludes1 note at F16.1, which applies to F16.159, lists "hallucinogen dependence (F16.2-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of F16.159?

Under the General Equivalence Mappings, hallucinogen abuse with hallucinogen-induced psychotic disorder, unspecified converts to ICD-9-CM 292.89 (drug mental disorder NEC). The mapping is approximate, so confirm the match fits the documentation.

What HCC is F16.159?

F16.159 (hallucinogen abuse with hallucinogen-induced psychotic disorder, unspecified) maps to CMS-HCC Category 135 (Drug Use with Psychotic Complications), commonly written as HCC 135, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 54 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.

Does F16.159 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, F16.159 adds a risk adjustment factor of about 0.424 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.297 to 1.181 depending on the payment segment). HCC 135 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 135 category page.