2027 ICD-10-CM Diagnosis Code F12.921Cannabis use, unspecified with intoxication delirium
ICD-10-CM Codes›F01–F99›F10-F19›F12
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Not Chronic
F12.921 is a billable ICD-10-CM diagnosis code for cannabis use, unspecified with intoxication delirium. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 894 through 897. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 463 closely related codes. Coders also document this condition as cannabis intoxication. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Cannabis-related disorders.
F12.921 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 55 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 55, ESRD (V21) category 55, and ESRD (V24) category 55 for payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
F12.921 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Cannabis intoxication
- Cannabis intoxication delirium
- Cannabis-induced organic mental disorder
- Delirium caused by cannabis
- Delirium caused by hallucinogen
- Delirium caused by synthetic cannabinoid
- Hallucinogen intoxication delirium
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to F12.921: its own notes plus those printed at F12.9, F12, and Chapter 5. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- marijuana
- disorders of psychological development
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name F12.921, its category, or a range that includes it.
Excludes1 2
These codes carry an Excludes1 note naming F12.921: they are not reported together with it, unless the two conditions are unrelated.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Cannabis
Cannabis, also known as marijuana, is a green, brown, or gray mixture of dried parts from the cannabis plant. The plant contains chemicals that affect the brain and can change how you feel or think.
The full article covers:
- What is cannabis?
- How do people use cannabis?
- What are the effects of cannabis?
- Can you overdose on cannabis?
- Is cannabis addictive?
- What is medical cannabis?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert F12.921 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About F12.921Overview
What is the ICD-10 code for cannabis use, unspecified with intoxication delirium?
The ICD-10-CM code for cannabis use, unspecified with intoxication delirium is F12.921 (sometimes written as F12921). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is F12.921 (Cannabis use, unspecified with intoxication) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report cannabis use, unspecified with intoxication delirium on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does F12.921 group to?
When cannabis use, unspecified with intoxication delirium is the principal diagnosis on an inpatient stay, it groups to MS-DRG 894, 897, 895, 896, with relative weights from 0.6272 to 1.6610 depending on complications. Higher weights mean higher Medicare reimbursement.
Is F12.921 a CC or MCC?
CMS lists F12.921 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 463 closely related codes in its exclusion list.
Can F12.921 be reported with a code from F12.1?
Not as a rule. The Excludes1 note at F12.9, which applies to F12.921, lists "cannabis abuse (F12.1-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
Does F12.921 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage. F12.921 mapped to HCC 55 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 55 (Drug/Alcohol Dependence), ESRD (V21) category 55 (Drug/Alcohol Dependence), and ESRD (V24) category 55 (Substance Use Disorder/Moderate/Severe/Substance Use with Complications).
