2024 ICD-10-CM Diagnosis Code T42.3X5S

Adverse effect of barbiturates, sequela

ICD-10-CM Code:
T42.3X5S
ICD-10 Code for:
Adverse effect of barbiturates, sequela
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs
        (T42)

T42.3X5S is a billable diagnosis code used to specify a medical diagnosis of adverse effect of barbiturates, sequela. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

T42.3X5S is a sequela code, includes a 7th character and should be used for complications that arise as a direct result of a condition like adverse effect of barbiturates. According to ICD-10-CM Guidelines a "sequela" code should be used for chronic or residual conditions that are complications of an initial acute disease, illness or injury. The most common sequela is pain. Usually, two diagnosis codes are needed when reporting sequela. The first code describes the nature of the sequela while the second code describes the sequela or late effect.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to barbitone
  • Adverse reaction to barbiturate
  • Adverse reaction to pentobarbitone
  • Amylobarbitone adverse reaction
  • Barbiturate antiepileptic adverse reaction
  • Butobarbitone adverse reaction
  • Cyclobarbitone adverse reaction
  • Methylphenobarbitone adverse reaction
  • Phenobarbital embryopathy
  • Phenobarbitone adverse reaction
  • Quinalbarbitone adverse reaction

Clinical Classification

Clinical Information

  • Barbital

    a long-acting barbiturate that depresses most metabolic processes at high doses. it is used as a hypnotic and sedative and may induce dependence. barbital is also used in veterinary practice for central nervous system depression.
  • Hexobarbital

    a barbiturate that is effective as a hypnotic and sedative.
  • Mephobarbital

    a barbiturate that is metabolized to phenobarbital. it has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
  • Pentobarbital

    a short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. it is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (from ama drug evaluations annual, 1994, p236)
  • Phenobarbital

    a barbituric acid derivative that acts as a nonselective central nervous system depressant. it potentiates gamma-aminobutyric acid action on gaba-a receptors, and modulates chloride currents through receptor channels. it also inhibits glutamate induced depolarizations.
  • Secobarbital

    a barbiturate that is used as a sedative. secobarbital is reported to have no anti-anxiety activity.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (T42). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)

T42.3X5S is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA IndicatorReason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Convert T42.3X5S to ICD-9-CM

  • ICD-9-CM Code: 909.5 - Lte efct advrs efct drug
    Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.
  • ICD-9-CM Code: E937.0 - Adv eff barbiturates
    Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.

Table of Drugs and Chemicals

The parent code T42.3X5 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AgrypnalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AllobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AllylisopropylmalonylureaT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AllypropymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AlurateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Amobarbital (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AmylobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Amytal (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AprobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BarbenylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbital
  »sodium
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbiturate NECT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbiturate NEC
  »with tranquilizer
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbiturate NEC
  »anesthetic (intravenous)
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BrallobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Butabarbital (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButabarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButabarpalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButalbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButallylonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButethalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Butisol (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Butobarbital
  »sodium
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
CarbritalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
CyclobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
CyclobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DelvinalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diallylbarbituric acidT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DiallymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DiemalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DiethylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »barbituric acid
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »carbamazine
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »carbinol
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »carbonate
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »ether (vapor) [See Also: ether]
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »oxide
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »propion
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »stilbestrol
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »toluamide (nonmedicinal)
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl
  »toluamide (nonmedicinal)
    »medicinal
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DifebarbamateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DormiralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EnhexymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EskabarbT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EthobralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EtilfenT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EtovalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EunerylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EvipalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Evipal
  »sodium
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EvipanT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Evipan
  »sodium
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
FebarbamateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
FenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
GardenalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
GardepanylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
GemonilT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HeptabarbT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HeptabarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HeptabarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HexemalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Hexethal (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HexobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Hexobarbital
  »rectal
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Hexobarbital
  »sodium
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
IpralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
LotusateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
LuminalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MeballymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MebaralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MebumalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MedinalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MedominT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MephebarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MephobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MetharbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MethituralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Methobarbital, methobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MethylhexabitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MethylphenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MysolineT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NealbarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NembutalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeravalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeravanT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeurobarbT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NoptilT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NunolT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Ortal (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PentobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Pentobarbital
  »sodium
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PentobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PentymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PernoctonT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PernostonT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phanodorm, phanodornT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhemitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenemalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenobalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital
  »with
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital
  »with
    »mephenytoin
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital
  »with
    »phenytoin
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital
  »sodium
T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenonylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenylmethylbarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ProbarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PropallylonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ProxibarbalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
QuinalbarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Quinalbarbitone sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SecbutabarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SecbutabarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SecobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SeconalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SomonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SonerylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
TalbutalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
VeramonT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
VeronalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Vinbarbital, vinbarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
VinylbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.