Version 2024
No Valid Principal Dx

2024 ICD-10-CM Diagnosis Code R53.83

Other fatigue

ICD-10-CM Code:
ICD-10 Code for:
Other fatigue
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
    • General symptoms and signs
      • Malaise and fatigue

R53.83 is a billable diagnosis code used to specify a medical diagnosis of other fatigue. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Asthenia
  • Asthenia
  • Difficulty eating
  • Difficulty eating due to fatigue
  • Exhausted on least exertion
  • Exhaustion
  • Exhaustion - physiological
  • Extreme exhaustion
  • Fatigability
  • Fatigability
  • Fatigue
  • Fatigue due to and following cerebrovascular accident
  • Fatigue due to and following cerebrovascular accident
  • Fatigue due to and following cerebrovascular accident with intracranial hemorrhage
  • Fatigue due to and following embolic cerebrovascular accident
  • Fatigue due to and following ischemic cerebrovascular accident
  • Fatigue due to chemotherapy
  • Fatigue due to radiation therapy
  • Fatigue due to treatment
  • Fatigue with AIDS
  • Finding of general energy
  • Finding of general energy
  • Finding of general stamina
  • Generally unwell
  • Heavy feeling
  • Increased need for rest
  • Lack of energy
  • Lack of energy
  • Lack of stamina
  • Lethargy
  • Malaise
  • Malaise and fatigue
  • Occasionally tired
  • Overwork
  • Postexertional fatigue
  • Quickly exhausted
  • Reduced level of fatigue
  • Sensation of heaviness in limbs
  • Tired
  • Tired
  • Tired
  • Tired
  • Tired on least exertion
  • Tires quickly
  • Underactive infant
  • Underexertion

Clinical Classification

Clinical Information

  • Asthenopia

    term generally used to describe complaints related to refractive error, ocular muscle imbalance, including pain or aching around the eyes, burning and itchiness of the eyelids, ocular fatigue, and headaches.
  • Auditory Fatigue

    loss of sensitivity to sounds as a result of auditory stimulation, manifesting as a temporary shift in auditory threshold. the temporary threshold shift, tts, is expressed in decibels.
  • Compassion Fatigue

    emotional distress caused by repeated or prolonged expression of compassion or empathy. it may occur in individuals working in care giving professions.
  • Fatigue

    the state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
  • Fatigue Syndrome, Chronic

    a syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. there is also considerable overlap between this condition and fibromyalgia. (from semin neurol 1998;18(2):237-42; ann intern med 1994 dec 15;121(12): 953-9)
  • Fractures, Stress

    fractures due to the strain caused by repetitive exercise. they are thought to arise from a combination of muscle fatigue and bone failure, and occur in situations where bone remodeling predominates over repair. the most common sites of stress fractures are the metatarsus; fibula; tibia; and femoral neck.
  • Heat Stress Disorders

    a group of conditions that develop due to overexposure or overexertion in excessive environmental heat.
  • Mental Fatigue

    a condition of low alertness or cognitive impairment, usually associated with prolonged mental activities or stress.
  • Muscle Fatigue

    a state arrived at through prolonged and strong contraction of a muscle. studies in athletes during prolonged submaximal exercise have shown that muscle fatigue increases in almost direct proportion to the rate of muscle glycogen depletion. muscle fatigue in short-term maximal exercise is associated with oxygen lack and an increased level of blood and muscle lactic acid, and an accompanying increase in hydrogen-ion concentration in the exercised muscle.
  • Voice Disorders

    pathological processes that affect voice production, usually involving vocal cords and the laryngeal mucosa. voice disorders can be caused by organic (anatomical), or functional (emotional or psychological) factors leading to dysphonia; aphonia; and defects in voice quality, loudness, and pitch.
  • Asthenia

    clinical sign or symptom manifested as debility, or lack or loss of strength and energy.
  • Neurocirculatory Asthenia

    a clinical syndrome characterized by palpitation, shortness of breath, labored breathing, subjective complaints of effort and discomfort, all following slight physical exertion. other symptoms may be dizziness, tremulousness, sweating, and insomnia. neurocirculatory asthenia is most typically seen as a form of anxiety disorder.
  • Lethargy

    a general state of sluggishness, listless, or uninterested, with being tired, and having difficulty concentrating and doing simple tasks. it may be related to depression or drug addiction.
  • Fibromyalgia

    a common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). muscle pain is typically aggravated by inactivity or exposure to cold. this condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, headaches, and occasionally depression. there is significant overlap between fibromyalgia and the chronic fatigue syndrome (fatigue syndrome, chronic). fibromyalgia may arise as a primary or secondary disease process. it is most frequent in females aged 20 to 50 years. (from adams et al., principles of neurology, 6th ed, p1494-95)
  • Fatigue, CTCAE 3.0|Fatigue (asthenia, lethargy, malaise)

    an unfavorable feeling of fatigue temporally associated with the use of a medical treatment or procedure.
  • Grade 1 Fatigue, CTCAE|CTCAE Grade 1 Fatigue (asthenia, lethargy, malaise)|Grade 1 Fatigue|Grade 1 Fatigue (asthenia, lethargy, malaise)

    fatigue relieved by rest
  • Grade 1 Malaise, CTCAE|Grade 1 Malaise

    uneasiness or lack of well being
  • Grade 2 Fatigue, CTCAE|CTCAE Grade 2 Fatigue (asthenia, lethargy, malaise)|Grade 2 Fatigue|Grade 2 Fatigue (asthenia, lethargy, malaise)

    fatigue not relieved by rest; limiting instrumental adl
  • Grade 2 Malaise, CTCAE|Grade 2 Malaise

    uneasiness or lack of well being limiting instrumental adl
  • Grade 3 Fatigue, CTCAE|CTCAE Grade 3 Fatigue (asthenia, lethargy, malaise)|Grade 3 Fatigue|Grade 3 Fatigue (asthenia, lethargy, malaise)

    fatigue not relieved by rest, limiting self care adl
  • Grade 3 Malaise, CTCAE|Grade 3 Malaise

    uneasiness or lack of well being limiting self-care adl
  • Malaise

    a feeling of general discomfort or uneasiness, an out-of-sorts feeling.
  • Malaise, CTCAE|Malaise|Malaise

    a disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling.
  • Post-Exertional Malaise|Post Exertional Malaise

    a feeling of malaise after physical or mental effort or stress.
  • Extreme Exhaustion

    extreme fatigue; inability to respond to stimuli.
  • How Often Experience Extreme Exhaustion|Frequency Experiencing Extreme Exhaustion|How often did you experience extreme exhaustion

    a question about how often an individual experiences or experienced extreme exhaustion.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert R53.83 to ICD-9-CM

  • ICD-9-CM Code: 780.79 - Malaise and fatigue NEC
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


Everyone feels tired now and then. Sometimes you may just want to stay in bed. But, after a good night's sleep, most people feel refreshed and ready to face a new day. If you continue to feel tired for weeks, it's time to see your doctor. He or she may be able to help you find out what's causing your fatigue and recommend ways to relieve it.

Fatigue itself is not a disease. Medical problems, treatments, and personal habits can add to fatigue. These include:

  • Taking certain medicines, such as antidepressants, antihistamines, and medicines for nausea and pain
  • Having medical treatments, like chemotherapy and radiation
  • Recovering from major surgery
  • Anxiety, stress, or depression
  • Staying up too late
  • Drinking too much alcohol or too many caffeinated drinks
  • Pregnancy

One disorder that causes extreme fatigue is chronic fatigue syndrome (CFS). This fatigue is not the kind of tired feeling that goes away after you rest. Instead, it lasts a long time and limits your ability to do ordinary daily activities.

NIH: National Institute on Aging

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.