2026 ICD-10-CM Diagnosis Code R69Illness, unspecified

ICD-10-CM Codes›R00–R99›R50-R69›R69

ICD-10-CM R69
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R69 is a billable ICD-10-CM diagnosis code for illness, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other general signs and symptoms.

Code Identity

ICD-10-CM Code
R69
Billable Status
Yes — Valid for Submission
Code Describes
Illness, unspecified
Chapter
R50-R69
General symptoms and signs

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR50-R69General symptoms and signs
CategoryR69Illness, unspecified
This CodeR69Illness, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acceptance of illness
  • Active disease following therapy
  • Acute disease
  • Acute megaloblastic anemia
  • Acute megaloblastic anemia due to severe illness
  • Acute pancreatitis due to systemic disease
  • Adverse incident outcome
  • Adverse incident resulting in potentially permanent but not disabling damage
  • Adverse incident resulting in potentially permanent disabling damage
  • Aplastic anemia due to chronic disease
  • Arthropathy associated with another systemic disease
  • Atrophic mucosa of digestive system organ
  • Beau's lines secondary to systemic illness
  • Bilateral glaucoma due to systemic syndrome
  • Bilateral ocular hypertension due to systemic syndrome
  • Biphasic disease
  • Cancer dataset administrative items
  • Cataract due to degenerative disorder
  • Chronic disease
  • Chronic disease present
  • Degenerative disorder
  • Degenerative sequelae of disorders
  • Delayed generalized tooth eruption due to systemic disease
  • Desquamation secondary to acute systemic illness
  • Disease activity following therapy, unassessed
  • Disease type AND/OR category unknown
  • Disorder confirmed
  • Disorder of pelvic region of trunk
  • Disorder of pelvis
  • Disorder of thoracic segment of trunk
  • Dysmotility of small intestine due to systemic disease
  • End stage organ failure
  • Endemic disease
  • Epidemic disease
  • Epididymitis associated with another disorder
  • Epididymo-orchitis associated with another disorder
  • Functional disease present
  • Functional disorder
  • Functional disorder present, condition terminal
  • Functional disorder present, investigation negative
  • Generalized enamel hypoplasia associated with systemic disease
  • Generalized functional disorder
  • Generalized redundant skin due to chronic disease
  • Generally unwell
  • Glaucoma due to systemic syndrome
  • Glaucoma of left eye due to systemic syndrome
  • Glaucoma of right eye due to systemic syndrome
  • Graft failure due to recurrent recipient disease
  • Home environment related disease
  • Illness
  • Inactive disease following therapy
  • Industrial environment related disease
  • Institutional environment related disease
  • Intercurrent disease
  • Interstitial lung disease due to systemic disease
  • Late tooth eruption
  • Local disease
  • Localized functional disorder
  • Looks ill
  • Maladaptive behavior associated with physical illness
  • Medically unfit to take examination at school
  • Motility disorder of small intestine
  • Multiple chronic diseases
  • Multiple supernumerary teeth related to systemic condition
  • Nail changes associated with systemic disease
  • Nature environment related disease
  • Ocular hypertension due to systemic syndrome
  • Ocular hypertension of left eye due to systemic syndrome
  • Ocular hypertension of right eye due to systemic syndrome
  • One chronic disease
  • Orchitis associated with another disorder
  • Organ dysfunction syndrome
  • Organic disease present
  • Periodontitis as manifestation of systemic disease
  • Peripheral vascular disease associated with another disorder
  • Persistent adverse event without recovery
  • Physical health problem
  • Pruritus due to systemic disorder
  • Pulmonary hypertension in systemic disorder
  • Radiotherapy course change due to progressive disease during radiotherapy
  • Reason for change in radiotherapy course
  • Recovered from adverse event with sequelae
  • Recurrent disease
  • Redundant skin
  • Renal disorders in systemic disease
  • Retinal dystrophy due to systemic disorder
  • Retinitis pigmentosa due to systemic disease
  • Secondary autoimmune hemolytic anemia
  • Secondary autoimmune hemolytic anemia co-occurrent and due to chronic inflammatory disease
  • Sequelae of inflammatory diseases
  • Serious physical health problem
  • Severe systemic illness respiratory muscle fatigue
  • Severe systemic illness tissue wasting
  • Severe systemic illness-induced intestinal villous atrophy
  • Severe systemic illness-induced respiratory muscle wasting
  • Severe systemic illness-induced skeletal muscle wasting
  • Subclinical disease AND/OR syndrome
  • Supernumerary teeth
  • Systemic disease
  • Systemic disease affecting skin
  • Terminal illness
  • Terminal illness - early stage
  • Terminal illness - late stage
  • Travel-related illness
  • Unable to attend school due to illness
  • Vasculitis due to systemic disease
  • Villous atrophy of intestine

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Unknown and unspecified causes of morbidity

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

  • - Illness - See Also: Disease; - R69

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Diagnosis deferred
    • Illness
    • Morbidity not stated or unknown
    • Sick
    • Undiagnosed(disease)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM016
Other general signs and symptoms
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Acute Disease

    disease having a short and relatively severe course.

  • Chronic Disease

    diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (dictionary of health services management, 2d ed). for epidemiological studies chronic disease often includes heart diseases; stroke; cancer; and diabetes (diabetes mellitus, type 2).

  • Chronic Disease Indicators

    a set of surveillance indicators of disease developed by consensus among the cdc, the council of state and territorial epidemiologists, and the national association of chronic disease directors. it enables public health professionals and policymakers to retrieve uniformly defined state and selected metropolitan-level data for chronic diseases and risk factors that impact public health.(https://www.cdc.gov/socialdeterminants/data/index.htm)

  • Hospitals, Chronic Disease

    hospitals which provide care to patients with long-term illnesses.

  • Noncommunicable Diseases

    diseases which are typically non-infectious in origin and do not transmit from an affected individual to others. the four main types of noncommunicable diseases are cardiovascular diseases (e.g., heart attacks and stroke), cancer, chronic respiratory diseases (e.g., chronic obstructive pulmonary disease and asthma) and diabetes mellitus.

  • Chronic Disease Management Service Type|Chronic Disease Management|Chronic Disease Management

    the service type that is associated with the health level 7 fast healthcare interoperability resources chronic disease management code.

  • Terminal Illness Service Type|Terminal Illness|Terminal Illness

    the service type that is associated with the health level 7 fast healthcare interoperability resources terminal illness code.

  • Anemia due to Chronic Disorder|Anemia of Chronic Disease|Anemia of Chronic Illness|Anemia of Chronic Inflammation

    anemia due to a disorder that is persistent or long-standing in nature.

  • Anemia in Other Chronic Diseases Classified Elsewhere|Anemia in Other chronic diseases classified elsewhere

    evidence of anemia in other chronic diseases classified elsewhere.

  • Chronic Disease

    a disease condition that persists over a significant span of time.

  • Family History of Chronic Disease|Other chronic diseases

    a history of a first-degree relative that has had a chronic disease.

  • Terminal Disease|Terminal Illness|terminal disease

    an illness that has a prognosis of death.

  • Terminal Illness

    an illness that has a prognosis of death.

  • Acute Disease

    a disease that is characterized by a sudden onset and short duration.

  • Chronic Disease Hospital Unit

    a hospital facility designed to evaluate, diagnose, and treat patients with a chronic condition.

Convert R69 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
799.89 Ill-define condition NEC
Approximate The match is approximate rather than exact.
ICD-9-CM
799.9 Unkn cause morb/mort NEC
Approximate The match is approximate rather than exact.
ICD-9-CM
V41.9 Probl w special func NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R69Overview

Is R69 (Illness, unspecified) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report illness, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Can R69 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the illness, unspecified is established, that condition takes the principal position instead.

What is the ICD-9 equivalent of R69?

Under the General Equivalence Mappings, illness, unspecified converts to ICD-9-CM 799.89 (ill-define condition NEC), 799.9 (unkn cause morb/mort NEC), and V41.9 (probl w special func NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.