ICD-10-CM Code T42.8X5

Adverse effect of antiparkinsonism drugs and other central muscle-tone depressants

Version 2020 Replaced Code Non-Billable Code Adverse Effect

Not Valid for Submission

T42.8X5 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of antiparkinsonism drugs and other central muscle-tone depressants. The code is NOT valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code T42.8X5 might also be used to specify conditions or terms like adverse reaction to antiparkinsonism drug, adverse reaction to central nervous system muscle-tone depressants, adverse reaction to chlorphenesin, adverse reaction to mephenesin, amantadine adverse reaction, baclofen adverse reaction, etc

ICD-10:T42.8X5
Short Description:Adverse effect of antiparkns drug/centr muscle-tone depr
Long Description:Adverse effect of antiparkinsonism drugs and other central muscle-tone depressants

Consider the following ICD-10 codes with a higher level of specificity:

  • T42.8X5A - Adverse effect of antiparkinsonism drugs and other central muscle-tone depressants, initial encounter
  • T42.8X5D - Adverse effect of antiparkinsonism drugs and other central muscle-tone depressants, subsequent encounter
  • T42.8X5S - Adverse effect of antiparkinsonism drugs and other central muscle-tone depressants, sequela

Replaced Code

This code was replaced in the 2020 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2019. This code was replaced for the FY 2020 (October 1, 2019 - September 30, 2020).

  • K59.03 - Drug induced constipation

Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to antiparkinsonism drug
  • Adverse reaction to central nervous system muscle-tone depressants
  • Adverse reaction to chlorphenesin
  • Adverse reaction to mephenesin
  • Amantadine adverse reaction
  • Baclofen adverse reaction
  • Benserazide + levodopa adverse reaction
  • Benztropine adverse reaction
  • Bromocriptine adverse reaction
  • Cabergoline adverse reaction
  • Carbidopa + levodopa adverse reaction
  • Carisoprodol adverse reaction
  • Dantrolene adverse reaction
  • Decarboxylase inhibitor adverse reaction
  • Dopaminergic drug used in parkinsonism adverse reaction
  • Ergoline drug adverse reaction
  • Ergoline drug adverse reaction
  • Ergoline drug adverse reaction
  • Ergoline drug adverse reaction
  • Ergoline drug adverse reaction
  • Levodopa adverse reaction
  • Lysuride adverse reaction
  • On - off phenomenon
  • Orphenadrine adverse reaction
  • Orphenadrine citrate adverse reaction
  • Orphenadrine hydrochloride adverse reaction
  • Pergolide adverse reaction
  • Quinagolide adverse reaction
  • Selegiline adverse reaction

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Antiepileptic, sedative- hypnotic and antiparkinsonism drugs (T42)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Table of Drugs and Chemicals

The code T42.8X5 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. Use as many codes as necessary to describe all reported drugs, medicinal or chemical substances.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
self-harm
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AfloqualoneT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
AmantadineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Antiparkinsonism drug NECT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Antirigidity drug NECT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
BaclofenT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
BenserazideT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
BenzatropineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
BromocriptineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
CabergolineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Carbidopa (with levodopa)T42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
CarisoprodolT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
ChlorphenesinT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Chlorphenesin
  »topical (antifungal)
T42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
ChlorzoxazoneT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
DantroleneT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
DeprenalinT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
DeprenylT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
DiethazineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
DifluoromethyldopaT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
DisipalT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
DopaT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
IdrocilamideT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
L-dopaT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
LevodopaT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Levodopa
  »with carbidopa
T42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
LisurideT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Mephenamin (e)T42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
MephenesinT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
MephenoxaloneT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
MesulergineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
MetaxaloneT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
MetergolineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
MethocarbamolT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Methocarbamol
  »skeletal muscle relaxant
T42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Muscle-tone depressant, central NECT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Muscle-tone depressant, central NEC
  »specified NEC
T42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
Orphenadrine (hydrochloride)T42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
PergolideT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
PhenprobamateT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
PiribedilT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
RelaT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
SelegilineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
SomaT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
StyramateT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
TizanidineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
TolserolT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6
ZoxazolamineT42.8X1T42.8X2T42.8X3T42.8X4T42.8X5T42.8X6

Information for Patients


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as ginkgo and blood thinners
  • Drugs and diseases, such as aspirin and peptic ulcers

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.


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