2026 ICD-10-CM Diagnosis Code C00.3Malignant neoplasm of upper lip, inner aspect

ICD-10-CM CodesC00–D49C00-C14C00

ICD-10-CM C00.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C00.3 is a billable ICD-10-CM diagnosis code for malignant neoplasm of upper lip, inner aspect. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 146 through 148. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Head and neck cancers - lip and oral cavity.

Code Identity

ICD-10-CM Code
C00.3
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm of upper lip, inner aspect
Short Description
Malignant neoplasm of upper lip, inner aspect
Same as the full description in the CMS dataset.
Parent Code
Malignant neoplasm of lip

Code Classification

ChapterC00–D49Neoplasms
SectionC00-C14Malignant neoplasms of lip, oral cavity and pharynx
CategoryC00Malignant neoplasm of lip
This CodeC00.3Malignant neoplasm of upper lip, inner aspect

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Carcinoma of frenum of lip
  • Carcinoma of frenum of upper lip
  • Malignant neoplasm of frenulum of upper lip
  • Malignant neoplasm of mucous membrane of upper lip
  • Neoplasm of frenulum of upper lip
  • Primary carcinoma of frenum of lip
  • Primary carcinoma of frenum of upper lip
  • Primary carcinoma of lip
  • Primary malignant neoplasm of inner aspect of lip
  • Primary malignant neoplasm of inner aspect of upper lip
  • Primary squamous cell carcinoma of lip
  • Primary squamous cell carcinoma of mucous membrane of lip
  • Primary squamous cell carcinoma of mucous membrane of upper lip
  • Squamous cell carcinoma of mucous membrane of upper lip

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Malignant neoplasm of buccal aspect of upper lip
  • Malignant neoplasm of frenulum of upper lip
  • Malignant neoplasm of mucosa of upper lip
  • Malignant neoplasm of oral aspect of upper lip

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO002
Head and neck cancers - lip and oral cavity
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
lip internal upperC00.3C79.89D00.01D10.0D37.01D49.0
lip upper internalC00.3C79.89D00.01D10.0D37.01D49.0

Patient EducationClinical

Oral Cancer

Oral cancer is cancer of the mouth. It is a type of head and neck cancer. Most oral cancers are squamous cell cancers. They begin in the flat cells that cover the surfaces of your mouth, tongue, and lips. The cancer cells may spread into deeper tissue as the cancer grows.

The full article covers:

  • What is oral cancer?
  • Who is more likely to develop oral cancer?
  • What are the symptoms of oral cancer?
  • How is oral cancer diagnosed?
  • What are the treatments for oral cancer?
  • Can oral cancer be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C00.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
140.3 Mal neo upper lip, inner
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C00.3Overview

Is C00.3 (Malignant neoplasm of lip) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of upper lip, inner aspect on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C00.3 group to?

When malignant neoplasm of upper lip, inner aspect is the principal diagnosis on an inpatient stay, it groups to MS-DRG 146, 147, 148, with relative weights from 0.7971 to 2.1174 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C00.3?

Under the General Equivalence Mappings, malignant neoplasm of upper lip, inner aspect converts to ICD-9-CM 140.3 (mal neo upper lip, inner). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.