ICD-10-CM Code First Notes · Chapter 21 · FY 2027 Z00-Z99

Code First Notes in Chapter 21: Factors influencing health status and contact with health services ICD-10-CM

A Code First note means the underlying condition named in the note is sequenced before this code. In Chapter 21 (Z00-Z99), notes printed in the chapter name other codes 30 times, and Code First Notes anywhere in the Tabular List name the chapter’s codes 3 times, covering 2 distinct codes, categories and ranges. Switch views to read the list either way.

✓ From the official FY 2027 ICD-10-CM Tabular ListDefinitions follow the Official Guidelines, Section I.A
30
References in Its Notes
3
References to Its Codes
2
Chapter Codes Named
Z00-Z99
Chapter 21
Chapter 21

Code First Notes by the code that carries the note

16 of 16 shown
  • Z15.0 Genetic susceptibility to malignant neoplasm applies to 9 codes
    • , if applicable, any current malignant neoplasm (C00-C75, C81-C96)
  • Z17 Estrogen, and other hormones and factors receptor status applies to 10 codes
    • malignant neoplasm of breast (C50.-)
    • malignant neoplasm of ovary (C56.-)
  • Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
    • Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)
  • Z3A Weeks of gestation applies to 38 codes
  • Z79.81 Long term (current) use of agents affecting estrogen receptors and estrogen levels applies to 3 codes
    • malignant neoplasm of breast (C50.-)
    • malignant neoplasm of prostate (C61)
  • Z85 Personal history of malignant neoplasm applies to 60 codes
    • any follow-up examination after treatment of malignant neoplasm (Z08)
  • Z86 Personal history of certain other diseases applies to 40 codes
    • any follow-up examination after treatment (Z09)
  • Z87 Personal history of other diseases and conditions applies to 54 codes
    • any follow-up examination after treatment (Z09)
  • Z91.12 Patient's intentional underdosing of medication regimen applies to 2 codes
    • underdosing of medication (T36-T50) with fifth or sixth character 6
  • Z91.13 Patient's unintentional underdosing of medication regimen applies to 2 codes
    • underdosing of medication (T36-T50) with fifth or sixth character 6
  • Z91.14 Patient's other noncompliance with medication regimen applies to 2 codes
    • , if applicable, adverse effect of underdosing (T36-T50)
  • Z91.83 Wandering in diseases classified elsewhere
  • Z91.A2 Caregiver's intentional underdosing of patient's medication regimen applies to 2 codes
    • underdosing of medication (T36-T50) with fifth or sixth character 6
  • Z91.A3 Caregiver's unintentional underdosing of patient's medication regimen
    • underdosing of medication (T36-T50) with fifth or sixth character 6
  • Z92.82 Status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility
    • acute cerebral infarction (I63.-)
    • acute myocardial infarction (I21.-, I22.-)
  • Z99.3 Dependence on wheelchair

The first view lists notes printed in this chapter (a note on a category or block applies to every code beneath it). The second lists codes of this chapter named by Code First Notes anywhere in the Tabular List, including notes in other chapters.

Questions About Code First Notes

What does a Code First note mean?

A Code First note means the underlying condition named in the note is sequenced before the code that carries the note. Under the etiology/manifestation convention, a “code first” note appears at the manifestation code and a “use additional code” note at the etiology code (Section I.A.13). The FY 2027 Tabular List has 810 of them; 600 name other codes, with 736 references to 429 distinct codes, categories and ranges.

Can a code with a Code First note be the principal diagnosis?

Not when it is a manifestation code. Codes titled “in diseases classified elsewhere” are never permitted as the first-listed or principal diagnosis; they must follow the underlying condition. The etiology and manifestation page lists them all.

Related References

Source: FY 2027 ICD-10-CM Tabular List (CMS and NCHS) and the ICD-10-CM Official Guidelines for Coding and Reporting FY 2027, Section I.A. ICD List is not affiliated with CMS or NCHS.