2027 ICD-10-CM Diagnosis Code I22Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction

ICD-10-CM Codes›I00–I99›I20-I25›STEMI

ICD-10-CM I22
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

I22 is a non-billable ICD-10-CM category code for subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction, so it cannot be submitted on claims. Use a more specific code from this category instead, such as I22.0, I22.1, I22.2, and I22.8.

Code Identity

ICD-10-CM Code
I22
Billable Status
No — Non-Billable Category
Code Describes
Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction
Short Description
Subsequent STEMI & NSTEMI mocard infrc
Chapter
I20-I25
Ischemic heart diseases

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI20-I25Ischemic heart diseases
CategorySTEMISubsequent ST elevation and non-ST elevation (NSTEMI) myocardial infarction (I22)
This CodeI22Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction

Specific Coding for Subsequent STEMI & NSTEMI mocard infrcOverview

Non-specific codes like I22 require more characters. Use one of these billable codes instead:

  • Use I22.0 for Subsequent ST elevation (STEMI) myocardial infarction of anterior wall

  • Use I22.1 for Subsequent ST elevation (STEMI) myocardial infarction of inferior wall

  • Use I22.2 for Subsequent non-ST elevation (NSTEMI) myocardial infarction

  • Use I22.8 for Subsequent ST elevation (STEMI) myocardial infarction of other sites

  • Use I22.9 for Subsequent ST elevation (STEMI) myocardial infarction of unspecified site

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to I22: its own notes plus those printed at block I20-I25 and Chapter 9. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

  • acute myocardial infarction occurring within four weeks (28 days) of a previous acute myocardial infarction, regardless of site
  • cardiac infarction
  • coronary (artery) embolism
  • coronary (artery) occlusion
  • coronary (artery) rupture
  • coronary (artery) thrombosis
  • infarction of heart, myocardium, or ventricle
  • recurrent myocardial infarction
  • reinfarction of myocardium
  • rupture of heart, myocardium, or ventricle
  • subsequent type 1 myocardial infarction

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

  • subsequent myocardial infarction, type 2 (I21.A1)
  • subsequent myocardial infarction of other type (type 3) (type 4) (type 5) (I21.A9)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 9 (I00-I99) Diseases of the circulatory system applies to 1,433 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • systemic connective tissue disorders (M30-M36)
  • transient cerebral ischemic attacks and related syndromes (G45.-)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

  • code, if applicable, to identify:
  • exposure to environmental tobacco smoke (Z77.22)
  • history of tobacco dependence (Z87.891)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Code Also

A second code may be needed to fully describe the condition; the note gives no sequencing direction.

From Block I20-I25 Ischemic heart diseases applies to 94 codes
  • the presence of hypertension (I10-I1A)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name I22, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming I22: they are not reported together with it, unless the two conditions are unrelated.

  • I25.82 Chronic total occlusion of coronary artery
    acute coronary occlusion with myocardial infarction (I21.0-I21.B, I22.-)

Excludes2 3

These codes carry an Excludes2 note naming I22: its condition is not part of those codes, and both may be reported when the patient has both.

  • I21 Acute myocardial infarction
    subsequent type 1 myocardial infarction (I22.-)
  • I74 Arterial embolism and thrombosis
    coronary embolism and thrombosis (I21-I25) names I21-I25, which includes this code
  • I82 Other venous embolism and thrombosis
    coronary (I21-I25) names I21-I25, which includes this code

Code First 1

These codes say to code first a condition named in the note, and I22 is one of the conditions named.

  • Z92.82 Status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility
    acute myocardial infarction (I21.-, I22.-)

Patient EducationClinical

Heart Attack

A heart attack, also called a myocardial infarction, is a type of heart disease. It happens when blood flow to the heart suddenly becomes blocked. Without the blood coming in, the heart can't get oxygen. If not treated quickly, the heart muscle begins to die.

The full article covers:

  • What is a heart attack?
  • What heart attack risk factors can be changed?
  • What heart attack risk factors can't be changed?
  • What causes a heart attack?
  • What are the symptoms of a heart attack?
  • How is a heart attack diagnosed?
  • What is the treatment for a heart attack?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About I22Overview

Is I22 a billable code?

No. This is a category header that groups the codes for subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction, and headers cannot be submitted on claims. Claims for subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction need a more specific code from this category, such as I22.0, I22.1, and I22.2.

Can I22 be reported with I21.A1?

Not as a rule. The Excludes1 note on I22 lists "subsequent myocardial infarction, type 2 (I21.A1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does I22 need an additional code?

When the condition applies, yes. The Use Additional Code note reads: code, if applicable, to identify: exposure to environmental tobacco smoke (Z77.22); history of tobacco dependence (Z87.891); occupational exposure to environmental tobacco smoke (Z57.31); status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82); tobacco dependence (F17.-); and 1 more listed in the Instructional Notes section. The additional code is reported after I22.