2024 ICD-10-CM Diagnosis Code Z83.49

Family history of other endocrine, nutritional and metabolic diseases

ICD-10-CM Code:
Z83.49
ICD-10 Code for:
Family history of endo, nutritional and metabolic diseases
Is Billable?
Yes - Valid for Submission
Code Navigator:

Code Classification

  • Factors influencing health status and contact with health services
    (Z00–Z99)
    • Persons with potential health hazards related to family and personal history and certain conditions influencing health status
      (Z77-Z99)
      • Family history of other specific disorders
        (Z83)

Z83.49 is a billable diagnosis code used to specify a medical diagnosis of family history of other endocrine, nutritional and metabolic diseases. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Family history of 5,10 methylenetetrahydrofolate reductase deficiency
  • Family history of acetylcholinesterase deficiency
  • Family history of Addison disease
  • Family history of alpha-1-antitrypsin deficiency
  • Family history of butyrylcholinesterase deficiency
  • Family history of Canavan disease
  • Family history of combined hyperlipidemia
  • Family history of cystic fibrosis
  • Family history of disorder of lung
  • Family history of endocrine disorders
  • Family history of eruptive xanthoma
  • Family history of galactosemia
  • Family history of glycogen storage disease
  • Family history of Graves disease
  • Family history of Hashimoto thyroiditis
  • Family history of hemochromatosis
  • Family history of hyperbetalipoproteinemia
  • Family history of hyperlipidemia
  • Family history of hyperparathyroidism
  • Family history of hyperthyroidism
  • Family history of hypertriglyceridemia
  • Family history of hypoalphalipoproteinemia
  • Family history of impaired glucose tolerance
  • Family history of metabolic disorder
  • Family history of methylmalonic aciduria
  • Family history of mitochondrial disease
  • Family history of movement disorder
  • Family history of neuropathy
  • Family history of nutritional disorder
  • Family history of phenylketonuria
  • Family history of polycystic ovary
  • Family history of tall stature
  • Family history of Tay-Sachs disease
  • Family history of tuberous xanthoma
  • Family history of vitamin B12 deficiency
  • Family history of vitamin D deficiency
  • Family history of Wilson disease
  • FH: Gout
  • FH: Hypercholesterolemia
  • FH: Hypercholesterolemia in first degree relative
  • FH: Hypothyroidism
  • FH: Liver disease
  • FH: Liver disease
  • FH: Nutritional deficiency
  • FH: Obesity
  • FH: Porphyria
  • FH: Raised blood lipids
  • FH: Thyroid disorder
  • Maternal nutritional disorder

Clinical Classification

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)

Z83.49 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA IndicatorReason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Convert Z83.49 to ICD-9-CM

  • ICD-9-CM Code: V18.19 - Fm hx endo/metab dis NEC
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:

  • Growth and development
  • Metabolism - digestion, elimination, breathing, blood circulation and maintaining body temperature
  • Sexual function
  • Reproduction
  • Mood

If your hormone levels are too high or too low, you may have a hormone disorder. Hormone diseases also occur if your body does not respond to hormones the way it is supposed to. Stress, infection and changes in your blood's fluid and electrolyte balance can also influence hormone levels.

In the United States, the most common endocrine disease is diabetes. There are many others. They are usually treated by controlling how much hormone your body makes. Hormone supplements can help if the problem is too little of a hormone.


[Learn More in MedlinePlus]

Family History

Your family history includes health information about you and your close relatives. Families have many factors in common, including their genes, environment, and lifestyle. Looking at these factors can help you figure out whether you have a higher risk for certain health problems, such as heart disease, stroke, and cancer.

Having a family member with a disease raises your risk, but it does not mean that you will definitely get it. Knowing that you are at risk gives you a chance to reduce that risk by following a healthier lifestyle and getting tested as needed.

You can get started by talking to your relatives about their health. Draw a family tree and add the health information. Having copies of medical records and death certificates is also helpful.

Centers for Disease Control and Prevention


[Learn More in MedlinePlus]

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat.

A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process. When this happens, you might have too much of some substances or too little of other ones that you need to stay healthy. There are different groups of disorders. Some affect the breakdown of amino acids, carbohydrates, or lipids. Another group, mitochondrial diseases, affects the parts of the cells that produce the energy.

You can develop a metabolic disorder when some organs, such as your liver or pancreas, become diseased or do not function normally. Diabetes is an example.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.