2026 ICD-10-CM Diagnosis Code R16Hepatomegaly and splenomegaly, not elsewhere classified

ICD-10-CM Codes›R00–R99›R10-R19›R16

ICD-10-CM R16
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R16 is a non-billable ICD-10-CM category code for hepatomegaly and splenomegaly, not elsewhere classified, so it cannot be submitted on claims. Use a more specific code from this category instead, such as R16.0, R16.1, and R16.2. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established.

Code Identity

ICD-10-CM Code
R16
Billable Status
No — Non-Billable Category
Code Describes
Hepatomegaly and splenomegaly, not elsewhere classified
Chapter
R10-R19
Symptoms and signs involving the digestive system and abdomen

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR10-R19Symptoms and signs involving the digestive system and abdomen
CategoryR16Hepatomegaly and splenomegaly, not elsewhere classified
This CodeR16Hepatomegaly and splenomegaly, not elsewhere classified

Specific Coding for Hepatomegaly and splenomegaly, not elsewhere classifiedOverview

Non-specific codes like R16 require more characters. Use one of these billable codes instead:

  • Use R16.0 for Hepatomegaly, not elsewhere classified

  • Use R16.1 for Splenomegaly, not elsewhere classified

  • Use R16.2 for Hepatomegaly with splenomegaly, not elsewhere classified

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Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R16Overview

Is R16 (Hepatomegaly and splenomegaly, not elsewhere classified) a billable code?

No. This is a category header that groups the codes for hepatomegaly and splenomegaly, not elsewhere classified, and headers cannot be submitted on claims. Claims for hepatomegaly and splenomegaly, not elsewhere classified need a more specific code from this category, such as R16.0, R16.1, and R16.2.

Can R16 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the hepatomegaly and splenomegaly, not elsewhere classified is established, that condition takes the principal position instead.