2026 ICD-10-CM Diagnosis Code M45.6Ankylosing spondylitis lumbar region

ICD-10-CM Codes›M00–M99›M45-M49›M45

ICD-10-CM M45.6
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

M45.6 is a billable ICD-10-CM diagnosis code for ankylosing spondylitis lumbar region. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 545 through 547. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Rheumatoid arthritis and related disease and Spondylopathies/spondyloarthropathy (including infective).

For Medicare Advantage risk adjustment, M45.6 maps to CMS-HCC Category 93 (Rheumatoid Arthritis and Other Specified Inflammatory Rheumatic Disorders) under the V28 model, adding a risk factor of about 0.617 for a community, non-dual, aged beneficiary in payment year 2026.

Code Identity

ICD-10-CM Code
M45.6
Billable Status
Yes — Valid for Submission
Code Describes
Ankylosing spondylitis lumbar region
Short Description
Ankylosing spondylitis lumbar region
Same as the full description in the CMS dataset.
Parent Code
Ankylosing spondylitis

Code Classification

ChapterM00–M99Diseases of the musculoskeletal system and connective tissue
SectionM45-M49Spondylopathies
CategoryM45Ankylosing spondylitis
This CodeM45.6Ankylosing spondylitis lumbar region

Medicare Risk Adjustment (HCC)Billing

M45.6 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2026.

CMS-HCC V28 Category (Payment Model)
HCC 93— Rheumatoid Arthritis and Other Specified Inflammatory Rheumatic Disorders
Payment HCC · PY 2026 one of 508 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.617
community, non-dual, aged · ranges 0.288–0.617 across segments
Hierarchy
Supersedes HCC 94
less severe related categories are not paid alongside HCC 93
Prior Model (CMS-HCC V24)
HCC 40
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 40 · ESRD (V21): HCC 40 · ESRD (V24): HCC 40
ESRD V21 weights: 0.072 dialysis, 0.274–0.398 functioning graft · ESRD V24 weights: 0.058 dialysis, 0.284–0.414 functioning graft
Part D (RxHCC)
RxHCC 83 — Rheumatoid Arthritis and Other Inflammatory Polyarthropathy
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MUS003
Rheumatoid arthritis and related disease
Default principal diagnosis: inpatient No · outpatient No
CCSR MUS011
Spondylopathies/spondyloarthropathy (including infective)
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Ankylosing Spondylitis

Ankylosing spondylitis (AS) is a type of arthritis of the spine. It causes inflammation (swelling) between your vertebrae (the bones that make up your spine) and the joints between your spine and pelvis. AS inflammation can cause stiffness and make it difficult to move and bend.

The full article covers:

  • What is ankylosing spondylitis?
  • Who is more likely to get ankylosing spondylitis?
  • What causes ankylosing spondylitis?
  • What are the symptoms of ankylosing spondylitis?
  • How is ankylosing spondylitis diagnosed?
  • What are the treatments for ankylosing spondylitis?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert M45.6 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
720.0 Ankylosing spondylitis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About M45.6Overview

What is the ICD-10 code for ankylosing spondylitis lumbar region?

The ICD-10-CM code for ankylosing spondylitis lumbar region is M45.6 (sometimes written as M456). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is M45.6 (Ankylosing spondylitis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report ankylosing spondylitis lumbar region on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does M45.6 group to?

When ankylosing spondylitis lumbar region is the principal diagnosis on an inpatient stay, it groups to MS-DRG 545, 546, 547, with relative weights from 0.8362 to 2.4817 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of M45.6?

Under the General Equivalence Mappings, ankylosing spondylitis lumbar region converts to ICD-9-CM 720.0 (ankylosing spondylitis). The mapping is approximate, so confirm the match fits the documentation.

What HCC is M45.6?

M45.6 (ankylosing spondylitis lumbar region) maps to CMS-HCC Category 93 (Rheumatoid Arthritis and Other Specified Inflammatory Rheumatic Disorders), commonly written as HCC 93, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2026. It mapped to HCC 40 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 83.

Does M45.6 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, M45.6 adds a risk adjustment factor of about 0.617 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.288 to 0.617 depending on the payment segment). HCC 93 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 93 category page.