2026 ICD-10-CM Diagnosis Code K52.9Noninfective gastroenteritis and colitis, unspecified

ICD-10-CM CodesK00–K95K50-K52K52

ICD-10-CM K52.9
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

K52.9 is a billable ICD-10-CM diagnosis code for noninfective gastroenteritis and colitis, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 391 through 392. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Noninfectious gastroenteritis.

Code Identity

ICD-10-CM Code
K52.9
Billable Status
Yes — Valid for Submission
Code Describes
Noninfective gastroenteritis and colitis, unspecified
Short Description
Noninfective gastroenteritis and colitis, unspecified
Same as the full description in the CMS dataset.
Parent Code
Other and unspecified noninfective gastroenteritis and colitis

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK50-K52Noninfective enteritis and colitis
CategoryK52Other and unspecified noninfective gastroenteritis and colitis
This CodeK52.9Noninfective gastroenteritis and colitis, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute and chronic colitis
  • Acute cecitis
  • Acute gastroenteritis
  • Arthritis of joint of spine due to inflammatory bowel disease
  • Arthritis temporally related to inflammatory bowel disease
  • Benign infantile seizure with mild gastroenteritis syndrome
  • Choanal atresia
  • Chronic colitis
  • Chronic diarrhea
  • Chronic diarrhea due to glucoamylase deficiency
  • Chronic diarrhea of infants AND/OR young children
  • Chronic diarrhea of unknown origin
  • Chronic diarrhea with villous atrophy syndrome
  • Chronic idiopathic non-infectious enteritis of intestine
  • Chronic non-specific colitis
  • Colitis
  • Congenital secretory diarrhea
  • Distal colitis
  • Diversion colitis
  • Enteritis of intestine
  • Enterocolitis
  • Exacerbation of non-infective colitis
  • Focal active colitis
  • Gastroenteritis
  • Hemophagocytic lymphohistiocytosis
  • Hemorrhage of colon
  • Hemorrhagic colitis
  • Hemorrhagic enteritis of intestine
  • Hemorrhagic gastroenteritis
  • Idiopathic colitis
  • IL21-related infantile inflammatory bowel disease
  • Ileitis
  • Immune dysregulation, inflammatory bowel disease, arthritis, recurrent infection syndrome
  • Infantile gastroenteritis
  • Inflammation of large intestine
  • Inflammatory bowel disease
  • Inflammatory bowel disease, recurrent sinopulmonary infection syndrome
  • Inflammatory disorder of digestive system
  • Inflammatory disorder of digestive tract
  • Inflammatory polyps co-occurrent and due to inflammatory bowel disease
  • Intractable diarrhea with choanal atresia and eye anomaly syndrome
  • Iritis co-occurrent with inflammatory bowel disease
  • Jejunitis
  • Juvenile arthritis of inflammatory bowel disease
  • Macrophage activation syndrome
  • Nonbacterial gastroenteritis of infant
  • Noninfectious colitis
  • Noninfectious enteritis due to autoimmune disease
  • Noninfectious enteritis of intestine
  • Noninfectious enteritis of intestine due to immunoglobulin A vasculitis
  • Noninfectious gastroenteritis
  • Noninfectious ileitis
  • Noninfectious jejunitis
  • Noninfectious sigmoiditis
  • Non-infective colitis due to graft-versus-host disease
  • Noninfective enteritis and colitis
  • Noninfective enteritis of intestine due to graft-versus-host disease
  • Non-specific colitis
  • Obesity, colitis, hypothyroidism, cardiac hypertrophy, developmental delay syndrome
  • Pericolitis
  • Periodic fever, infantile enterocolitis, autoinflammatory syndrome
  • Perisigmoiditis
  • Phlegmonous enteritis of duodenum
  • Phlegmonous enteritis of gastrointestinal tract
  • Pyoderma gangrenosum due to inflammatory bowel disease
  • Secretory diarrhea
  • Seronegative arthritis secondary to inflammatory bowel disease
  • Sigmoiditis
  • Transient neonatal colitis
  • Typhlitis
  • Vasculitis due to inflammatory bowel disease
  • Vasculitis due to systemic disease
  • Villous atrophy of intestine

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Colitis NOS
  • Enteritis NOS
  • Gastroenteritis NOS
  • Ileitis NOS
  • Jejunitis NOS
  • Sigmoiditis NOS

Type 1 Excludes

  • diarrhea NOS R19.7
  • functional diarrhea K59.1
  • infectious gastroenteritis and colitis NOS A09
  • neonatal diarrhea noninfective P78.3
  • psychogenic diarrhea F45.8

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Cecitis
    • Colitis(acute) (catarrhal) (chronic) (noninfective) (hemorrhagic)
    • Colitis(acute) (catarrhal) (chronic) (noninfective) (hemorrhagic)
      • noninfective
    • Diarrhea, diarrheal(disease) (infantile) (inflammatory)
      • chronic (noninfectious)
    • Diarrhea, diarrheal(disease) (infantile) (inflammatory)
      • noninfectious
    • Enteritis(acute) (diarrheal) (hemorrhagic) (noninfective)
    • Enteritis(acute) (diarrheal) (hemorrhagic) (noninfective)
      • chronic (noninfectious)
    • Enteritis(acute) (diarrheal) (hemorrhagic) (noninfective)
      • noninfectious
    • Enterocolitis
    • Enterocolitis
      • noninfectious
    • Gastroenteritis(acute) (chronic) (noninfectious)
    • Gastroenteritis(acute) (chronic) (noninfectious)
      • noninfectious
    • Gastroenteropathy
    • Gastrojejunitis
    • Ileitis(chronic) (noninfectious)
    • Ileocolitis
    • Sigmoiditis
    • Sigmoiditis
      • noninfectious

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR DIG022
Noninfectious gastroenteritis
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Choanal Atresia

    a congenital abnormality that is characterized by a blocked choanae, the opening between the nose and the nasopharynx. blockage can be unilateral or bilateral; bony or membranous.
  • Gastroenteritis

    inflammation of any segment of the gastrointestinal tract from esophagus to rectum. causes of gastroenteritis are many including genetic, infection, hypersensitivity, drug effects, and cancer.
  • Gastroenteritis, Transmissible, of Swine

    a condition of chronic gastroenteritis in adult pigs and fatal gastroenteritis in piglets caused by a coronavirus.
  • Murine hepatitis virus

    a species of the coronavirus genus causing hepatitis in mice. four strains have been identified as mhv 1, mhv 2, mhv 3, and mhv 4 (also known as mhv-jhm, which is neurotropic and causes disseminated encephalomyelitis with demyelination as well as focal liver necrosis).
  • Transmissible gastroenteritis virus

    a species of coronavirus causing a fatal disease to pigs under 3 weeks old.
  • Macrophage Activation Syndrome

    a serious complication of childhood systemic inflammatory disorders that is thought to be caused by excessive activation and proliferation of t-lymphocytes and macrophages. it is seen predominantly in children with systemic onset juvenile idiopathic arthritis.
  • Enterocolitis

    inflammation of the mucosa of both the small intestine and the large intestine. etiology includes ischemia, infections, allergic, and immune responses.
  • Enterocolitis, Necrotizing

    enterocolitis with extensive ulceration (ulcer) and necrosis. it is observed primarily in low birth weight infant.
  • Enterocolitis, Neutropenic

    a syndrome characterized by inflammation in the ileum, the cecum, and the ascending colon. it is observed in cancer patients with chemotherapy-induced neutropenia or in other immunocompromised individuals (immunocompromised host).
  • Enterocolitis, Pseudomembranous

    an acute inflammation of the intestinal mucosa that is characterized by the presence of pseudomembranes or plaques in the small intestine (pseudomembranous enteritis) and the large intestine (pseudomembranous colitis). it is commonly associated with antibiotic therapy and clostridium difficile colonization.
  • Crohn Disease

    a chronic transmural inflammation that may involve any part of the digestive tract from mouth to anus, mostly found in the ileum, the cecum, and the colon. in crohn disease, the inflammation, extending through the intestinal wall from the mucosa to the serosa, is characteristically asymmetric and segmental. epithelioid granulomas may be seen in some patients.
  • Ileitis

    inflammation of any segment of the ileum and the ileocecal valve.
  • Pouchitis

    acute inflammation in the intestinal mucosa of the continent ileal reservoir (or pouch) in patients who have undergone ileostomy and restorative proctocolectomy (proctocolectomy, restorative).
  • Typhlitis

    necrotizing inflammation of the cecum (typhlon in greek), sometimes spreading to the appendix and/or the ileum. symptoms include abdominal pain and diarrhea. its pathogenesis is multifactorial. typhlitis is often associated with neutropenia and chemotherapy in immunocompromised individuals (immunocompromised host).
  • Colitis

    inflammation of the colon section of the large intestine (intestine, large), usually with symptoms such as diarrhea (often with blood and mucus), abdominal pain, and fever.
  • Colitis, Collagenous

    a subtype of microscopic colitis, characterized by chronic watery diarrhea of unknown origin, a normal colonoscopy but abnormal histopathology on biopsy. microscopic examination of biopsy samples taken from the colon show larger-than-normal band of subepithelial collagen.
  • Colitis, Ischemic

    inflammation of the colon due to colonic ischemia resulting from alterations in systemic circulation or local vasculature.
  • Colitis, Lymphocytic

    a subtype of microscopic colitis, characterized by chronic watery diarrhea of unknown origin, a normal colonoscopy but abnormal histopathology on biopsy. microscopic examination of biopsy samples taken from the colon show infiltration of lymphocytes in the superficial epithelium and the underlying connective tissue (lamina propria).
  • Colitis, Microscopic

    a condition characterized by chronic watery diarrhea of unknown origin, a normal colonoscopy but abnormal histopathology on biopsy. this syndrome was first described in 1980 by read and associates. subtypes include collagenous colitis and lymphocytic colitis. both have similar clinical symptoms and are distinguishable only by histology.
  • Colitis, Ulcerative

    inflammation of the colon that is predominantly confined to the mucosa. its major symptoms include diarrhea, rectal bleeding, the passage of mucus, and abdominal pain.
  • Colitis-Associated Neoplasms

    colonic neoplasms associated with chronic inflammation conditions such as ulcerative colitis and crohn disease.
  • Cytomegalovirus Infections

    infection with cytomegalovirus, characterized by enlarged cells bearing intranuclear inclusions. infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults.
  • Dysentery, Amebic

    dysentery caused by intestinal amebic infection, chiefly with entamoeba histolytica. this condition may be associated with amebic infection of the liver and other distant sites.
  • Irritable Bowel Syndrome

    a disorder with chronic or recurrent colonic symptoms without a clearcut etiology. this condition is characterized by chronic or recurrent abdominal pain, bloating, mucus in feces, and an erratic disturbance of defecation.
  • Coronavirus

    a member of coronaviridae which causes respiratory or gastrointestinal disease in a variety of vertebrates.
  • Cytomegalovirus

    a genus of the family herpesviridae, subfamily betaherpesvirinae, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. infection with cytomegalovirus is also seen as an opportunistic infection in aids.
  • Enterocolitis Infectious, CTCAE|Enterocolitis Infectious|Enterocolitis infectious

    a disorder characterized by an infectious process involving the small and/or large intestines.
  • Immunotherapy-Related Enterocolitis|Immune Therapy Related Enterocolitis|Immunotherapy Related Enterocolitis

    enterocolitis associated with the use of immunotherapeutic agents.
  • AIDS-Related Enterocolitis

    enterocolitis associated with the aids virus.
  • Enterocolitis

    an inflammatory process affecting the small intestine and colon. causes include viruses, bacteria, radiation, and antibiotics use.
  • Enterocolitis Infectious, CTCAE|Enterocolitis Infectious|Enterocolitis infectious

    a disorder characterized by an infectious process involving the small and large intestines.
  • Enterocolitis, CTCAE|Enterocolitis|Enterocolitis

    a disorder characterized by inflammation of the small and large intestines.
  • Grade 1 Enterocolitis, CTCAE|Grade 1 Enterocolitis

    asymptomatic; clinical or diagnostic observations only; intervention not indicated
  • Grade 2 Enterocolitis Infectious, CTCAE|Grade 2 Enterocolitis infectious

    passage of >3 unformed stools per 24 hrs or duration of illness >48 hrs; moderate abdominal pain; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)
  • Grade 2 Enterocolitis, CTCAE|Grade 2 Enterocolitis

    abdominal pain; mucus or blood in stool
  • Grade 3 Enterocolitis Infectious, CTCAE|Grade 3 Enterocolitis infectious

    iv antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; profuse watery diarrhea with signs of hypovolemia; bloody diarrhea; fever; severe abdominal pain; hospitalization indicated
  • Grade 3 Enterocolitis, CTCAE|Grade 3 Enterocolitis

    severe or persistent abdominal pain; fever; ileus; peritoneal signs
  • Grade 3 Necrotizing Enterocolitis, AE|Grade 3 Necrotizing Enterocolitis|Grade 3 Necrotizing Enterocolitis, Adverse Event

    an adverse event in a newborn characterized by confirmed necrotizing enterocolitis; major care change indicated (e.g. npo, antibiotics, non-urgent surgery).
  • Grade 4 Enterocolitis Infectious, CTCAE|Grade 4 Enterocolitis infectious

    life-threatening consequences; urgent intervention indicated
  • Grade 4 Enterocolitis, CTCAE|Grade 4 Enterocolitis

    life-threatening consequences; urgent intervention indicated
  • Grade 4 Necrotizing Enterocolitis, AE|Grade 4 Necrotizing Enterocolitis|Grade 4 Necrotizing Enterocolitis, Adverse Event

    a necrotizing enterocolitis adverse event in a newborn characterized by bowel perforation (pneumoperitoneum)(modified bell stage iiib); shock, disseminated intravascular coagulation (dic), combined respiratory and metabolic acidosis (modified bell stage iiia); urgent major care change indicated.
  • Grade 5 Enterocolitis Infectious, CTCAE|Grade 5 Enterocolitis infectious

    death
  • Grade 5 Enterocolitis, CTCAE|Grade 5 Enterocolitis

    death
  • Grade 5 Necrotizing Enterocolitis, AE|Grade 5 Necrotizing Enterocolitis|Grade 5 Necrotizing Enterocolitis, Adverse Event

    a necrotizing enterocolitis adverse event in a newborn which results in death.
  • Infectious Enterocolitis|Enterocolitis infectious

    an infectious process affecting the small and large intestines. symptoms include diarrhea, cramping abdominal pain, and fever.
  • Necrotizing Enterocolitis Totalis

    a severe and often fatal form of necrotizing enterocolitis, in which diffuse ischemia, necrosis, and pneumatosis intestinalis are evident in the small and large intestine. short bowel syndrome is common among survivors.
  • Necrotizing Enterocolitis, AE|Necrotizing Enterocolitis|Necrotizing Enterocolitis, Adverse Event|Necrotizing enterocolitis neonatal

    an adverse event in newborns characterized by extensive mucosal ulceration, pseudomembrane formation, submucosal hemorrhage, and necrosis in the intestines .
  • Necrotizing Enterocolitis|NEC|NEC|Necrotizing Enterocolitis in Fetus or Newborn|Necrotizing Enterocolitis in Fetus or Newborn

    a fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal hemorrhage, and necrosis usually of the right colon, cecum, terminal ileum, and appendix, possibly due to perinatal intestinal ischemia and bacterial invasion. progression can lead to necrosis, perforation and/or scarring of the intestinal tract.
  • Non-Infectious Gastroenterocolitis

    an inflammatory disease of the stomach and intestines due to a non-infectious cause.
  • Suspected Necrotizing Enterocolitis

    the diagnosis assigned when a health care practitioner feels strongly the patient has necrotizing enterocolitis, but lacks definitive proof.
  • Crohn Ileitis|Crohn's Ileitis

    crohn's disease affecting the ileum.
  • Ileitis

    inflammation of the ileum.
  • Rutgeerts Score RUTG0101 Original Result - Diffuse Aphthous Ileitis With Diffusely Inflamed Mucosa|RUTG0101-diffuse aphthous ileitis with diffusely inflamed mucosa|diffuse aphthous ileitis with diffusely inflamed mucosa

    rutgeerts score rutg0101 original result - diffuse aphthous ileitis with diffusely inflamed mucosa.
  • Enteropathic Arthritis

    a form of chronic arthritis that is found in some patients with inflammatory bowel disease.

Patient EducationClinical

Digestive Diseases

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Convert K52.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
558.9 Noninf gastroenterit NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About K52.9Overview

Is K52.9 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report noninfective gastroenteritis and colitis, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does K52.9 group to?

When noninfective gastroenteritis and colitis, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 391, 392, with relative weights from 0.7796 to 1.2683 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of K52.9?

Under the General Equivalence Mappings, noninfective gastroenteritis and colitis, unspecified converts to ICD-9-CM 558.9 (noninf gastroenterit NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.