2027 ICD-10-CM Diagnosis Code E59Dietary selenium deficiency

ICD-10-CM Codes›E00–E89›E50-E64›E59

ICD-10-CM E59
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E59 is a billable ICD-10-CM diagnosis code for dietary selenium deficiency. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 640 through 641. Coders also document this condition as deficiency of selenium AND/OR vitamin E. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nutritional deficiencies.

Code Identity

ICD-10-CM Code
E59
Billable Status
Yes — Valid for Submission
Code Describes
Dietary selenium deficiency
Short Description
Dietary selenium deficiency
Same as the full description in the CMS dataset.
Chapter
E50-E64
Other nutritional deficiencies

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE50-E64Other nutritional deficiencies
CategoryE59Dietary selenium deficiency
This CodeE59Dietary selenium deficiency

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Deficiency of selenium AND/OR vitamin E
  • Dietary deficiency of selenium AND vitamin E
  • Dietary selenium deficiency
  • Inadequate intake of selenium
  • Keshan disease
  • Selenium deficiency
  • Vitamin E deficiency

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E59: its own notes plus those printed at block E50-E64 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Keshan disease

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E59 itself
  • sequelae of selenium deficiency (E64.8)
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block E50-E64 Other nutritional deficiencies applies to 50 codes

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E59, its category, or a range that includes it.

Applicable To 1

These notes mention E59.

  • P00.4 Newborn affected by maternal nutritional disorders
    Newborn affected by maternal disorders classifiable to E40-E64 names E40-E64, which includes this code

Excludes1 3

These codes carry an Excludes1 note naming E59: they are not reported together with it, unless the two conditions are unrelated.

  • E83 Disorders of mineral metabolism
    dietary mineral deficiency (E58-E61) names E58-E61, which includes this code
  • R79.0 Abnormal level of blood mineral
    nutritional mineral deficiency (E58-E61) names E58-E61, which includes this code
  • Z72.4 Inappropriate diet and eating habits
    malnutrition and other nutritional deficiencies (E40-E64) names E40-E64, which includes this code

Code First 1

These codes say to code first a condition named in the note, and E59 is one of the conditions named.

  • G63 Polyneuropathy in diseases classified elsewhere
    nutritional deficiency (E40-E64) names E40-E64, which includes this code

Notes 1

These notes mention E59.

  • E64 Sequelae of malnutrition and other nutritional deficiencies
    This category is to be used to indicate conditions in categories E43, E44, E46, E50-E63 as the cause of sequelae, which are themselves classified elsewhere. The 'sequelae' include conditions specified as such; they also include the late effects of diseases classifiable to the above categories if the disease itself is no longer present names E50-E63, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END007
Nutritional deficiencies
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Malnutrition

Malnutrition means that your body isn't getting enough calories or the right balance of nutrients to stay healthy. This can happen if you don't get enough protein, carbohydrates, and fats, eat too much unhealthy food, or don't get the vitamins and minerals your body needs.

The full article covers:

  • What is malnutrition?
  • What are the types of malnutrition?
  • What causes malnutrition?
  • Who is at risk for developing malnutrition?
  • What are the symptoms of malnutrition?
  • How is malnutrition diagnosed?
  • What are the treatments for malnutrition?
  • Can malnutrition be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E59 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
269.3 Mineral deficiency NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E59Overview

What is the ICD-10 code for dietary selenium deficiency?

The ICD-10-CM code for dietary selenium deficiency is E59. It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is E59 (Dietary selenium deficiency) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report dietary selenium deficiency on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does E59 group to?

When dietary selenium deficiency is the principal diagnosis on an inpatient stay, it groups to MS-DRG 641, 640, with relative weights from 0.7864 to 1.3392 depending on complications. Higher weights mean higher Medicare reimbursement.

Can E59 be reported with E64.8?

Not as a rule. The Excludes1 note on E59 lists "sequelae of selenium deficiency (E64.8)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of E59?

Under the General Equivalence Mappings, dietary selenium deficiency converts to ICD-9-CM 269.3 (mineral deficiency NEC). The mapping is approximate, so confirm the match fits the documentation.