2026 ICD-10-CM Diagnosis Code E59Dietary selenium deficiency

ICD-10-CM Codes›E00–E89›E50-E64›E59

ICD-10-CM E59
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E59 is a billable ICD-10-CM diagnosis code for dietary selenium deficiency. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 640 through 641. Coders also document this condition as deficiency of selenium AND/OR vitamin E. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nutritional deficiencies.

Code Identity

ICD-10-CM Code
E59
Billable Status
Yes — Valid for Submission
Code Describes
Dietary selenium deficiency
Chapter
E50-E64
Other nutritional deficiencies

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE50-E64Other nutritional deficiencies
CategoryE59Dietary selenium deficiency
This CodeE59Dietary selenium deficiency

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Deficiency of selenium AND/OR vitamin E
  • Dietary deficiency of selenium AND vitamin E
  • Dietary selenium deficiency
  • Inadequate intake of selenium
  • Keshan disease
  • Selenium deficiency
  • Vitamin E deficiency

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Keshan disease

Type 1 Excludes

  • sequelae of selenium deficiency E64.8

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Deficiency, deficient
      • selenium (dietary)
    • Disease, diseased
      • Keshan
    • Keshan disease
    • Selenium deficiency, dietary

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END007
Nutritional deficiencies
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Vitamin E Deficiency

    a nutritional condition produced by a deficiency of vitamin e in the diet, characterized by posterior column and spinocerebellar tract abnormalities, areflexia, ophthalmoplegia, and disturbances of gait, proprioception, and vibration. in premature infants vitamin e deficiency is associated with hemolytic anemia, thrombocytosis, edema, intraventricular hemorrhage, and increasing risk of retrolental fibroplasia and bronchopulmonary dysplasia. an apparent inborn error of vitamin e metabolism, named familial isolated vitamin e deficiency, has recently been identified. (cecil textbook of medicine, 19th ed, p1181)

  • Vitamins

    organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.

Patient EducationClinical

Malnutrition

Malnutrition means that your body isn't getting enough calories or the right balance of nutrients to stay healthy. This can happen if you don't get enough protein, carbohydrates, and fats, eat too much unhealthy food, or don't get the vitamins and minerals your body needs.

The full article covers:

  • What is malnutrition?
  • What are the types of malnutrition?
  • What causes malnutrition?
  • Who is at risk for developing malnutrition?
  • What are the symptoms of malnutrition?
  • How is malnutrition diagnosed?
  • What are the treatments for malnutrition?
  • Can malnutrition be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E59 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
269.3 Mineral deficiency NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E59Overview

Is E59 (Dietary selenium deficiency) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report dietary selenium deficiency on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E59 group to?

When dietary selenium deficiency is the principal diagnosis on an inpatient stay, it groups to MS-DRG 640, 641, with relative weights from 0.7782 to 1.3356 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E59?

Under the General Equivalence Mappings, dietary selenium deficiency converts to ICD-9-CM 269.3 (mineral deficiency NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.