2026 ICD-10-CM Diagnosis Code E10.641Type 1 diabetes mellitus with hypoglycemia with coma

ICD-10-CM Codes›E00–E89›E08-E13›E10

ICD-10-CM E10.641
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E10.641 is a billable ICD-10-CM diagnosis code for type 1 diabetes mellitus with hypoglycemia with coma. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 637 through 639. Coders also document this condition as hypoglycemia due to type 1 diabetes mellitus. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coma; stupor; and brain damage; Diabetes mellitus with complication; and Diabetes mellitus, Type 1.

Code Identity

ICD-10-CM Code
E10.641
Billable Status
Yes — Valid for Submission
Code Describes
Type 1 diabetes mellitus with hypoglycemia with coma
Short Description
Type 1 diabetes mellitus with hypoglycemia with coma
Same as the full description in the CMS dataset.
Parent Code
E10.64
Type 1 diabetes mellitus with hypoglycemia

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE08-E13Diabetes mellitus
CategoryE10Type 1 diabetes mellitus
This CodeE10.641Type 1 diabetes mellitus with hypoglycemia with coma

Quality Payment Program MeasuresBilling

Medicare quality measures that can apply when E10.641 is part of the patient record.

Diabetes: Hemoglobin A1c (HbA1c) Poor Control (>9%)

High Priority: YES

Measure Type: Intermediateoutcome

Submission Methods: Claims, Electronic Health Record, Cms Web Interface, Registry

Description: Percentage of patients 18-75 years of age with diabetes who had hemoglobin A1c > 9.0% during the measurement period.

View Measure

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Hypoglycemia due to type 1 diabetes mellitus
  • Hypoglycemic coma due to diabetes mellitus
  • Hypoglycemic coma due to type 1 diabetes mellitus

Coding GuidelinesGuidance

The diabetes mellitus codes are combination codes that include the type of diabetes mellitus, the body system affected, and the complications affecting that body system. As many codes within a particular category as are necessary to describe all of the complications of the disease may be used. They should be sequenced based on the reason for a particular encounter. Assign as many codes from categories E08 - E13 as needed to identify all of the associated conditions that the patient has.

The age of a patient is not the sole determining factor, though most type 1 diabetics develop the condition before reaching puberty. For this reason type 1 diabetes mellitus is also referred to as juvenile diabetes.

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Diabetes, diabetic(mellitus) (sugar)
      • type 1
        • with
          • coma due to
            • hypoglycemia
    • Diabetes, diabetic(mellitus) (sugar)
      • type 1
        • with
          • hypoglycemia
            • with coma

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS013
Coma; stupor; and brain damage
Default principal diagnosis: inpatient No · outpatient No
CCSR END003
Diabetes mellitus with complication
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR END004
Diabetes mellitus, Type 1
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Coma

A coma is a deep state of unconsciousness. An individual in a coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a result of injuries, such as brain injury.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E10.641 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
250.31 DMI o cm nt st uncntrld
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E10.641Overview

Is E10.641 (Type 1 diabetes mellitus with hypoglycemia) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report type 1 diabetes mellitus with hypoglycemia with coma on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E10.641 group to?

When type 1 diabetes mellitus with hypoglycemia with coma is the principal diagnosis on an inpatient stay, it groups to MS-DRG 637, 638, 639, with relative weights from 0.6212 to 1.4367 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E10.641?

Under the General Equivalence Mappings, type 1 diabetes mellitus with hypoglycemia with coma converts to ICD-9-CM 250.31 (DMI o cm nt st uncntrld). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.