2026 ICD-10-CM Diagnosis Code E10.52Type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene

ICD-10-CM Codes›E00–E89›E08-E13›E10

ICD-10-CM E10.52
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E10.52 is a billable ICD-10-CM diagnosis code for type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 299 through 301. Coders also document this condition as gangrene due to diabetes mellitus. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Diabetes mellitus with complication; Diabetes mellitus, Type 1; and Gangrene.

Code Identity

ICD-10-CM Code
E10.52
Billable Status
Yes — Valid for Submission
Code Describes
Type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene
Short Description
Type 1 diabetes w diabetic peripheral angiopathy w gangrene
Parent Code
E10.5
Type 1 diabetes mellitus with circulatory complications

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE08-E13Diabetes mellitus
CategoryE10Type 1 diabetes mellitus
This CodeE10.52Type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene

Quality Payment Program MeasuresBilling

Medicare quality measures that can apply when E10.52 is part of the patient record.

Diabetes: Hemoglobin A1c (HbA1c) Poor Control (>9%)

High Priority: YES

Measure Type: Intermediateoutcome

Submission Methods: Claims, Electronic Health Record, Cms Web Interface, Registry

Description: Percentage of patients 18-75 years of age with diabetes who had hemoglobin A1c > 9.0% during the measurement period.

View Measure

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Gangrene due to diabetes mellitus
  • Gangrene due to type 1 diabetes mellitus

Coding GuidelinesGuidance

The diabetes mellitus codes are combination codes that include the type of diabetes mellitus, the body system affected, and the complications affecting that body system. As many codes within a particular category as are necessary to describe all of the complications of the disease may be used. They should be sequenced based on the reason for a particular encounter. Assign as many codes from categories E08 - E13 as needed to identify all of the associated conditions that the patient has.

The age of a patient is not the sole determining factor, though most type 1 diabetics develop the condition before reaching puberty. For this reason type 1 diabetes mellitus is also referred to as juvenile diabetes.

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Type 1 diabetes mellitus with diabetic gangrene

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Diabetes, diabetic(mellitus) (sugar)
      • type 1
        • with
          • gangrene
    • Diabetes, diabetic(mellitus) (sugar)
      • type 1
        • with
          • peripheral angiopathy
            • with gangrene

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END003
Diabetes mellitus with complication
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR END004
Diabetes mellitus, Type 1
Default principal diagnosis: inpatient No · outpatient No
CCSR CIR028
Gangrene
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Diabetes Type 1

Diabetes means your blood glucose, or blood sugar, levels are too high. With type 1 diabetes, your pancreas does not make insulin. Insulin is a hormone that helps glucose get into your cells to give them energy. Without insulin, too much glucose stays in your blood.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E10.52 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
250.71 DMI circ nt st uncntrld
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
443.81 Angiopathy in other dis
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
785.4 Gangrene
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E10.52Overview

Is E10.52 (Type 1 diabetes mellitus with circulatory complications) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E10.52 group to?

When type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene is the principal diagnosis on an inpatient stay, it groups to MS-DRG 299, 300, 301, with relative weights from 0.7197 to 1.6327 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E10.52?

Under the General Equivalence Mappings, type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene converts to ICD-9-CM 250.71 (DMI circ nt st uncntrld), 443.81 (angiopathy in other dis), and 785.4 (gangrene). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.